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Current Cancer Drug Targets

Volume 20, 11 Issues, 2020
ISSN: 1873-5576 (Online)
ISSN: 1568-0096 (Print)
This journal supports open access
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  • 135th of 229 in

    Oncology

In the current Pandemic scenario, all articles related to Coronavirus will be processed on a free, quick track basis, to ensure timely review and publication of much needed research

Aims & Scope

Current Cancer Drug Targets aims to cover all the latest and outstanding developments on the medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular drug targets involved in cancer, e.g. disease specific proteins, receptors, enzymes and genes.

Current Cancer Drug Targets publishes original research articles, letters, reviews / mini-reviews, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics on drug targets involved in cancer.

As the discovery, identification, characterization and validation of novel human drug targets for anti-cancer drug discovery continues to grow; this journal has become essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Cancer Drug Targets

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Volume 20

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Number 4



Biography   Open Access



Review Article



Review Article



Review Article



Research Article



Research Article



Research Article



Articles Ahead of Print







Synthesis and Cytotoxic Activity of Azine Derivatives of 6- Hydroxyxanthanodiene


Margarita E. Neganova, Sergey G. Klochkov, Sergey A. Pukhov, Svetlana V. Afanasieva, Yulia R. Aleksandrova, Ekaterina Yu. Yandulova, Marco Avila-Rodriguez, Liudmila M. Mikhaleva, Vladimir N. Nikolenko, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/1568009620999200421200338
View Abstract View on PubMed




Immune Checkpoint Regulators: A New Era Toward Promising Cancer Therapy


Mohammed Shaaban, Heba Othman, Takwa Ibrahim, Mariam Ali, Mohamed Abdelmoaty, Abdel-Rahman Abdel-Kawi, Ahmed Mostafa, Aya El Nakeeb, Heba Emam and Alaa Refaat*


DOI: 10.2174/1568009620666200422081912
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice









Exploring Proteomic Drug Targets, Therapeutic Strategies and Protein - Protein Interactions in Cancer: Mechanistic View

, 2019; 19(6): 430 - 448

Khalid Bashir Dar, Aashiq Hussain Bhat, Shajrul Amin, Syed Anjum, Bilal Ahmad Reshi, Mohammad Afzal Zargar, Akbar Masood and Showkat Ahmad Ganie*


DOI: 10.2174/1568009618666180803104631




Open Access Articles

Cancer Cell-derived Secretory Factors in Breast Cancer-associated Lung Metastasis: Their Mechanism and Future Prospects

, 2020; 20(3): 168 - 186

Tabinda Urooj*, Bushra Wasim, Shamim Mushtaq, Syed Nudrat Nawaid Shah and Muzna Shah





Linc01638 Promotes Tumorigenesis in HER2+ Breast Cancer

, 2019; 19(1): 74 - 80

Peng Liu, Hailin Tang, Jiali Wu, Xingsheng Qiu, Yanan Kong, Lijuan Zhang, Xinhua Xie* and Xiangsheng Xiao*




Role of MicroRNAs in Treatment Response in Prostate Cancer

, 2018; 18(10): 929 - 944

Anshuli Razdan, Paul de Souza* and Tara Laurine Roberts




Noxa: Role in Cancer Pathogenesis and Treatment

, 2018; 18(10): 914 - 928

Rami Z. Morsi, Rouba Hage-Sleiman, Hadile Kobeissy and Ghassan Dbaibo*








Platycodin D Induces Tumor Growth Arrest by Activating FOXO3a Expression in Prostate Cancer in vitro and in vivo

, 2014; 14(9): 860 - 871

Rui Zhou, Zongliang Lu, Kai Liu, Jing Guo, Jie Liu, Yong Zhou, Jian Yang, Mantian Mi and Hongxia Xu




Pleiotropic Role of HSF1 in Neoplastic Transformation

, 2014; 14(2): 144 - 155

Natalia Vydra, Agnieszka Toma and Wieslawa Widlak






β-Catenin Knockdown in Liver Tumor Cells by a Cell Permeable Gamma Guanidine-based Peptide Nucleic Acid

, 2013; 13(8): 867 - 878

Evan Delgado, Raman Bahal, Jing Yang, Jung M. Lee, Danith H Ly and Satdarshan P. S. Monga




Signal Transduction in Human Cutaneous Melanoma and Target Drugs

, 2013; 13(8): 843 - 866

Anatoly B. Uzdensky, Svetlana V. Demyanenko and Mikhail Y. Bibov





Most Cited Articles

Review Article

Polyploid giant cancer cells (PGCCs): The evil roots of cancer

, 2019; 19(5): 360-367.

Junsong Chen, Na Niu, Jing Zhang, Lisha Qi , Weiwei Shen , Krishna Vanaja Donkena, Zhenqing Feng and Jinsong Liu *


DOI: 10.2174/1568009618666180703154233


Review Article

Epigenetics in metastatic breast cancer: Its regulation and implications in diagnosis, prognosis and therapeutics

, 2019; 19(2): 82-100.

Yuan Seng Wu, Zhong Yang Lee , Lay-Hong Chuah, Chun Wai Mai and Siew Ching Ngai*


DOI: 10.2174/1568009618666180430130248



Research Article

c-Myc inhibitor 10074-G5 induces murine and human hematopoietic stem and progenitor cell expansion and HDR modulator Rad51 expression

, 2019; 19(6): 479-494.

Merve Aksoz, Esra Albayrak, Galip Servet Aslan, Raife Dilek Turan, Lamia Yazgi Alyazici, Pınar Siyah, Emre Can Tuysuz, Serli Canikyan, Dogacan Yucel, Neslihan Meric, Zafer Gulbas, Fikrettin Sahin and Fatih Kocabas*


DOI: 10.2174/1568009618666180905100608


Review Article

Challenges and opportunities from basic cancer biology for nanomedicine for targeted drug delivery

, 2019; 19(4): 257-276.

Xiaodong Xie, Yingying Zhang, Fengqiao Li, Tingting Lv, Ziying Li, Haijun Chen, Lee Jia* and Yu Gao*


DOI: 10.2174/1568009618666180628160211



Review Article

Glycolysis inhibition as a strategy for hepatocellular carcinoma treatment?

, 2019; 19(1): 26-40.

A.P. Alves, A.C. Mamede, M.G. Alves, P.F. Oliveira, S.M. Rocha, M.F. Botelho and C.J. Maia*


DOI: 10.2174/1568009618666180430144441



Review Article

Ursolic acid in cancer treatment and metastatic chemoprevention: From synthesized derivatives to nanoformulations in preclinical studies

, 2019; 19(4): 245-256.

Junjie Zou, Juanfang Lin, Chao Li, Ruirui Zhao, Lulu Fan, Jesse Yu and Jingwei Shao*


DOI: 10.2174/1568009618666181016145940


Review Article

Focal adhesion kinase in ovarian cancer: A potential therapeutic target for platinum and taxane-resistant tumors

, 2019; 19(3): 179-188.

Arkene Levy*, Khalid Alhazzani, Priya Dondapati, Ali Alaseem, Khadijah Cheema, Keerthi Thallapureddy, Paramjot Kaur, Saad Alobid and Appu Rathinavelu


DOI: 10.2174/1568009618666180706165222



Letter

Cathepsin l induces proangiogenic changes in human omental microvascular endothelial cells via activation of the ERK1/2 pathway

, 2019; 19(3): 231-242.

Md Zahidul I. Pranjol, Nicholas J. Gutowski, Michael Hannemann and Jacqueline L. Whatmore*


DOI: 10.2174/1568009618666180831123951



Systemic Review Article

Crizotinib versus chemotherapy on ALK-positive NSCLC: A systematic review of efficacy and safety

, 2019; 19(1): 41-49.

Mingxia Wang, Guanqi Wang, Haiyan Ma and Baoen Shan*


DOI: 10.2174/1568009617666170623115846




Most Accessed Articles



Multiple Myeloma and the Immune Microenvironment

, 2017; 17(9): 806-818.

Yawara Kawano, Aldo. M. Roccaro, Irene M. Ghobrial* and Jamil Azzi*


DOI: 10.2174/1568009617666170214102301


Mechanism and Treatment of Rituximab Resistance in Diffuse Large Bcell Lymphoma

, 2019; 19(9): 681-687.

Linqing Zou, Guoqi Song, Siyu Gu, Lingling Kong, Shiqi Sun, Li Yang* and William C. Cho*


DOI: 10.2174/1568009619666190126125251


C/EBPα Regulates FOXC1 to Modulate Tumor Growth by Interacting with PPARγ in Hepatocellular Carcinoma

, 2020; 20(1): 59-66.

Zhuo Xu, Shao-Hua Meng, Jian-Guo Bai, Chao Sun*, Li-Li Zhao*, Rui-Feng Tang, Zhao-Lin Yin, Jun-Wei Ji, Wei Yang and Guang-Jun Ma


DOI: 10.2174/1568009619666190912161003



Antibody Based EpCAM Targeted Therapy of Cancer, Review and Update

, 2018; 18(9): 857-868.

Shirin Eyvazi, Safar Farajnia*, Siavoush Dastmalchi, Farzad Kanipour, Habib Zarredar and Mojghan Bandehpour


DOI: 10.2174/1568009618666180102102311


The Role of Shcbp1 in Signaling and Disease

, 2019; 19(11): 854-862.

Geng-Yuan Zhang, Zhi-Jian Ma, Long Wang, Ruo-Fei Sun, Xiang-Yan Jiang, Xu-Juan Yang, Bo Long, Hui-Li Ye, Shu-Ze Zhang, Ze-Yuan Yu, Wen-Gui Shi and Zuo-Yi Jiao*


DOI: 10.2174/1568009619666190620114928


Study of Serum Soluble Programmed Death Ligand 1 as a Prognostic Factor in Hepatocellular Carcinoma in Egyptian Patients

, 2019; 19(11): 896-905.

Fatma El-Gebaly , Sabry Abou-saif , Mahmoud Elkadeem, Amal Helmy, Sherief Abd-Elsalam *, Mohamed Yousef, Reham Abdelkader Elkhouly, Ibrahim Fathi Amer and Taher El-Demerdash


DOI: 10.2174/1568009619666190718141647




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