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Current Drug Targets

Volume 20, 16 Issues, 2019
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

Ranking and Category

  • 131st of 267 in

    Pharmacology & Pharmacy

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Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

,

Volume 20

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Number 14



Review Article



Review Article



Review Article

Circulating and Tissue microRNAs as Biomarkers for Ovarian Cancer Prognosis

, 20(14): 1447 - 1460

Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, Maryam Ghandehari, Malihe Hasanzadeh, Seyed Mohammad Reza Parizadeh, Seyed Mahdi Hassanian, Afsaneh Rezaei-Kalat, Amirsaeed Sabeti Aghabozorgi, Rana Rahimi-Kakhki, Bita Zargaran, Gordon A Ferns and Amir Avan*


DOI: 10.2174/1389450120666190708100308


Review Article



Review Article



Review Article

Personalized Peptide-based Vaccination for Treatment of Colorectal Cancer: Rational and Progress

, 20(14): 1486 - 1495

Seyed Mostafa Parizadeh, Reza Jafarzadeh-Esfehani, Maryam Ghandehari, Afsaneh Rezaei-Kalat, Seyed Mohammad Reza Parizadeh, Afsane Javanbakht, Seyed Mahdi Hassanian, Gordon A. Ferns, Majid Khazaei and Amir Avan*


DOI: 10.2174/1389450120666190619121658


Review Article (Mini-Review)



Current Drug Targets, Volume 20 (2019) - Number 15


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Advances in the Discovery of PDE10A Inhibitors for CNS-Related Disorders. Part 2: Focus on Schizophrenia


Artur Świerczek, Agnieszka Jankowska, Grażyna Chłoń-Rzepa, Maciej Pawłowski and Elżbieta Wyska*


DOI: 10.2174/1389450120666190801114210
View Abstract View on PubMed


Molecular and Biological Functions of Melatonin in Endometrial Cancer


Parisa Maleki Dana, Fatemeh Sadoughi, Moein Mobini, Rana Shafabakhsh, Shala Chaichian, Bahram Moazzami, Maryam Chamani and Zatollah Asemi*


DOI: 10.2174/1389450120666190927123746
View Abstract View on PubMed




The Use of Chemical Compounds to Identify the Regulatory Mechanisms of Vertebrate Circadian Clocks


Yoshimi Okamoto-Uchida, Akari Nishimura*, Junko Izawa, Atsuhiko Hattori, Nobuo Suzuki and Jun Hirayama


DOI: 10.2174/1389450120666190926143120
View Abstract View on PubMed




Ion Channels as Therapeutic Targets for Type 1 Diabetes Mellitus


Chandrabose Selvaraj*, Gurudeeban Selvaraj, Satyavani Kaliamurthi, William C Cho, Dong-Qing Wei* and Sanjeev Kumar Singh*


DOI: 10.2174/1389450119666190920152249
View Abstract View on PubMed


Antiviral Drug Targets of Single-Stranded RNA Viruses Causing Chronic Human Diseases


Dhurvas Chandrasekaran Dinesh*, Selvaraj Tamilarasan, Kaushik Rajaram and Evžen Bouřa


DOI: 10.2174/1389450119666190920153247
View Abstract View on PubMed


Abstracts Ahead of Print

Exploring the Clinical Impact of Predictive Biomarkers in Serous Ovarian Carcinomas


Cécile Le Page*, Jacqueline Chung, Kurosh Rahimi, Martin Kobel, Diane Provencher and Anne- Marie Mes- Masson


DOI: 10.2174/1389450120666191016143836
View Abstract









Published Contents

Editor's Choice

Anti-TNF and Postoperative Complications in Abdominal Crohn's Disease Surgery

, 2019; 20(13): 1339 - 1348

Takayuki Yamamoto*, Fabio Vieira Teixeira, Rogerio Saad-Hossne, Paulo Gustavo Kotze and Silvio Danese


DOI: 10.2174/1389450120666190404144048





The Use of Naltrexone in Dermatology. Current Evidence and Future Directions

, 2019; 20(10): 1058 - 1067

Mariusz Sikora*, Adriana Rakowska, Małgorzata Olszewska and Lidia Rudnicka


DOI: 10.2174/1389450120666190318121122





Targeting Water in the Brain: Role of Aquaporin-4 in Ischemic Brain Edema

, 2019; 20(7): 748 - 755

Muyassar Mamtilahun, Guanghui Tang, Zhijun Zhang, Yongting Wang, Yaohui Tang* and Guo-Yuan Yang*


DOI: 10.2174/1389450120666190214115309



Estrogen Receptor Alpha and its Ubiquitination in Breast Cancer Cells

, 2019; 20(6): 690 - 704

Angeles C. Tecalco-Cruz*, Josué O. Ramírez-Jarquín and Eduardo Cruz-Ramos


DOI: 10.2174/1389450119666181015114041



Understanding Membrane Protein Drug Targets in Computational Perspective

, 2019; 20(5): 551 - 564

Jianting Gong, Yongbing Chen, Feng Pu, Pingping Sun, Fei He, Li Zhang, Yanwen Li*, Zhiqiang Ma* and Han Wang*


DOI: 10.2174/1389450120666181204164721



Influence of Ultrafine Particles Exposure on Asthma Exacerbation in Children: A Meta-Analysis

, 2019; 20(4): 412 - 420

Qinyuan Li, Qian Yi, Lin Tang, Siying Luo, Yuan Tang, Guangli Zhang and Zhengxiu Luo*


DOI: 10.2174/1389450119666180829114252



Open Access Articles

Current Understanding of Group A Streptococcal Biofilms

, 2019; 20(9): 982 - 993

Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*








Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20: 1 - 7 (E-Pub Ahead of Print)

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J Castellino




Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga





Most Cited Articles

Review Article

Cytochrome P450 structure, function and clinical significance: A review

, 2018; 19(1): 38-54.

Palrasu Manikandan and Siddavaram Nagini*


DOI: 10.2174/1389450118666170125144557


Review Article

Cyclin-dependent kinase 2 in cellular senescence and cancer. A structural and functional review

, 2019; 20(7): 716-726.

Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *


DOI: 10.2174/1389450120666181204165344



Review Article

Flavonoids and its neuroprotective effects on brain ischemia and neurodegenerative diseases

, 2018; 19(14): 1710-1720.

Manish Putteeraj, Wei Ling Lim, Seong Lin Teoh and Mohamad Fairuz Yahaya*


DOI: 10.2174/1389450119666180326125252


Review Article

Recent advances in protein tyrosine phosphatase 1b targeted drug discovery for Type II diabetes and obesity

, 1 April 2018; 19(5): 551-575.

Neelesh Maheshwari, Chandrabose Karthikeyan, Piyush Trivedi and N.S. Hari Narayana Moorthy*


DOI: 10.2174/1389450118666170222143739


Review Article

Stimuli-responsive smart liposomes in cancer targeting

, 1 March 2018; 19(3): 259-270.

Ankit Jain and Sanjay K. Jain*


DOI: 10.2174/1389450117666160208144143


Review Article

Nanoparticles in cancer treatment: Opportunities and obstacles

, 2018; 19(14): 1696-1709.

Rajendra Awasthi*, Ariane Roseblade, Philip Michael Hansbro, Michael John Rathbone, Kamal Dua and Mary Bebawy*


DOI: 10.2174/1389450119666180326122831


Review Article

GRP78 influences chemoresistance and prognosis in cancer

, 2018; 19(6): 701-708.

Jenifer B. Gifford and Reginald Hill*


DOI: 10.2174/1389450118666170615100918


Review Article

Insights into the targeting potential of thymoquinone for therapeutic intervention against triple-negative breast cancer

, 2018; 19(1): 70-80.

Md Abul Barkat, Harshita, Javed Ahmad, Mohammad Ahmed Khan*, Sarwar Beg* and Farhan Jalees Ahmad*


DOI: 10.2174/1389450118666170612095959


Review Article

Metformin, a new era for an old drug in the treatment of immune mediated disease?

, 2018; 19(8): 945-959.

Mark Schuiveling, Nadia Vazirpanah, Timothy R.D.J. Radstake, Maili Zimmermann* and Jasper C.A. Broen*


DOI: 10.2174/1389450118666170613081730



Review Article

CDK9 as an appealing target for therapeutic interventions

, 2019; 20(4): 453-464.

Shirin Eyvazi, Mohammad Saeid Hejazi, Homan Kahroba, Mozghan Abasi, Reza Eghdam Zamiri and Vahideh Tarhriz*


DOI: 10.2174/1389450119666181026152221


Review Article

Antitumor activity of polysaccharides: An overview

, 2018; 19(1): 89-96.

Ling Chen and Gangliang Huang*


DOI: 10.2174/1389450118666170704143018


Review Article

Blood eosinophils as biomarkers to drive treatment choices in asthma and COPD

, 2018; 19(16): 1882-1896.

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*


DOI: 10.2174/1389450119666180212120012


Review Article

Complexation of bioelements and toxic metals by polyphenolic compounds – Implications for health

, 2018; 19(14): 1612-1638.

Sylwia Borowska*, Malgorzata Michalina Brzoska* and Michal Tomczyk


DOI: 10.2174/1389450119666180403101555



Most Accessed Articles




Loss of the Tumor Suppressor HACE1 Contributes to Cancer Progression

, 2019; 20(10): 1018-1028.

Jun-Chen Li, Xing Chang, Yang Chen, Xin-Zhe Li, Xiang-Lian Zhang, Shi-Ming Yang, Chang-Jiang Hu* and Hao Zhang*


DOI: 10.2174/1389450120666190227184654



Photopolymerizable Resins for 3D-Printing Solid-Cured Tissue Engineered Implants

, 2019; 20(8): 823-838.

Antonio J. Guerra, Hernan Lara-Padilla, Matthew L. Becker, Ciro A. Rodriguez and David Dean*


DOI: 10.2174/1389450120666190114122815



Molecular Aspects of Melatonin Treatment in Tinnitus: A Review

, 2019; 20(11): 1112-1128.

Azam Hosseinzadeh, Seyed Kamran Kamrava, Brian C.J. Moore, Russel J. Reiter, Habib Ghaznavi, Mahboobeh Kamali and Saeed Mehrzadi*


DOI: 10.2174/1389450120666190319162147



Age-related Macular Degeneration: Current Knowledge of Zinc Metalloproteinases Involvement

, 2019; 20(9): 903-918.

Francesca Liva, Doretta Cuffaro, Elisa Nuti, Susanna Nencetti, Elisabetta Orlandini, Giovanni Vozzi and Armando Rossello*


DOI: 10.2174/1389450120666190122114857




Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
USA

View Full Editorial Board

Journal History

Current Drug Targets Journal was launched in 2000. Dr. Francis J. Castellino serves as the Editor-in-Chief of the journal.
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Scopus CiteScore Metrics: 1.63

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