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Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Anti-Inflammatory and Anti-Allergy Agents

Volume 20, 4 Issues, 2021
ISSN: 1875-614X (Online)
ISSN: 1871-5230 (Print)
This journal supports open access

Aims & Scope

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new anti-inflammatory & anti-allergy agents.

The journal publishes full-length/mini reviews, original research articles, drug clinical trial studies and special topic issues. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in the field.

Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry

,

Volume 20

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Number 2





Review Article (Mini-Review)

Covid-19: Urgent Call to Action

, 20(2): 118 - 122

Amal A. Mohamed, Omnia I. Tantawi, Lamiaa A. Fathalla, Dalia M. Abd El-Hassib, Naglaa El-Toukhy R. El-Toukhy, Wafaa Salah, Mahmoud Elkadeem, Omnia Ezzat and Sherief Abd-Elsalam*


DOI: 10.2174/1871523019666201202092859






Research Article

C1 Inhibitor Administration Reduces Local Inflammation and Capillary Leakage, Without Affecting Long-term Wound Healing Parameters, in a Pig Burn Wound Model

, 20(2): 150 - 160

Halil Ibrahim Korkmaz*, Magda M.W. Ulrich, Wessel N. Van Wieringen, Hatice Doǧan, Marcel Vlig, Reindert W. Emmens, Klaas W. Meyer, Paul Sinnige, Sacha Zeerleder, Diana Wouters, Marieke S. Van Ham, Paul P.M. Van Zuijlen, Paul A.J. Krijnen and Hans W.M. Niessen


DOI: 10.2174/1871523019666200702101513


Research Article

Modulation of Proinflammatory Bacteria- and Lipid-Coupled Intracellular Signaling Pathways in a Transwell Triple Co-Culture Model by Commensal Bifidobacterium Animalis R101-8

, 20(2): 161 - 181

Darab Ghadimi*, Annegret Nielsen, Mohamed Farghaly Yoness Hassan, Regina Fölster-Holst, Michael Ebsen, Sven Olaf Frahm, Christoph Röcken, Michael de Vrese and Knut J. Heller


DOI: 10.2174/1871523019999201029115618




Research Article

Predictive and Prognostic Value of Ascitic Fluid Mannose Binding Lectin in Patients with Spontaneous Bacterial Peritonitis

, 20(2): 196 - 200

Amal A. Mohamed, Mohamed Abdelhamid, Naglaa El-Toukhy, Ahmed Sabry, Rania A. Khattab, Dalia Ali El-damasy, Abeer Ahmed, Mahmoud Elkadeem and Sherief Abd-Elsalam*


DOI: 10.2174/1871523019666200617132513


Articles Ahead of Print

Effects of Xenogen Mesenchymal Stem Cells and Cryo-Platelet Gel on Intractable Wound Healing in Animal Model (Rat)


Babak Alavi-Farzaneh, Ali Shojaeian, Mehdi Banitalebi-Dehkordi*, Fatemeh Mirahmadi, Ameneh Mehri-Ghahfarrokhi, Alireza Ghorbanpour, Shima Rahmati-Dehkordi and Farshad Yazdani


DOI: 10.2174/1871523020666210514002722
View Abstract View on PubMed





In-silico Prediction of the Beta-carboline Alkaloids Harmine and Harmaline as Potent Drug Candidates for the Treatment of Parkinson’s disease


Rumpa Banerjee, Mukesh Kumar, Isha Gaurav*, Sudha Thakur, Abhimanyu Thakur, Kunal Singh, Sanchari Karak, Rajeswar Das and Mohit Chhabra


DOI: 10.2174/1871523019999201111192344
View Abstract View on PubMed




Triazol-phenyl Antipyretic Derivatives Inhibit mPGES-1 mRNA Levels in LPS-Induced RAW 264.7 Macrophage Cells


Lenisa Dandara dos Santos, Thamires Quadros Froes, Miriam Cristina Contin de Melo, Gloria Emília Petto de Souza, Denis de Melo Soares and Marcelo Santos Castilho*


DOI: 10.2174/1871523019999201208202831
View Abstract View on PubMed




Abstracts Ahead of Print



Parvovirus B19 Seroprevalence in Women with Bad Obstetric History in Kirkuk.


Abdulghani Mohamed Alsamarai*, Hala Majeed Hassan, Mohamed Almoustafa Alsamarai and Zainab Khalil Aljumaili


DOI: 10.2174/1871523020666210727142351
View Abstract


Identification of phytoconstituents of Tragia involucrata leaf extracts and evaluate their correlation with anti-inflammatory & antioxidant properties


Vinodhini Velu, Swagata Banerjee, Vidya Radhakrishnan, Gaurav Gupta, Dinesh Kumar Chellappan, Neeraj Kumar, Shivkanya Fuloria, Meenu Mehta, Kamal Dua* and Himaja Malipeddi*


DOI: 10.2174/1871523020666210126144506
View Abstract


Published Contents

Editor's Choice


Molecular Modelling, Synthesis and Evaluation of Flavone and Flavanone Scaffolds as Anti-inflammatory Agents

, 2021; 20(1): 20 - 38

Natarajan Kiruthiga*, Manikandan Alagumuthu, Chellappa Selvinthanuja, Kulandaivel Srinivasan and Thangavel Sivakumar


DOI: 10.2174/1871523019666200102112017



Synthesis and Biological Activity of a Bis-steroid-methanocyclobutanaphthalene- dione Derivative against Ischemia/Reperfusion Injury via Calcium Channel Activation

, 2020; 19(4): 393 - 412

Figueroa-Valverde Lauro*, Diaz-Cedillo Francisco, Rosas-Nexticapa Marcela*, Mateu-Armand Virginia, Garcimarero-Espino E. Alejandra, Lopez-Ramos Maria, Hau-Heredia Lenin, Borges-Ballote Yaritza and Cabrera-Tuz Jhair


DOI: 10.2174/1871523018666191003152854



Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents

, 2020; 19(3): 254 - 267

Tatyana S. Khlebnicova*, Yuri A. Piven, Fedor A. Lakhvich, Iryna V. Sorokina, Tatiana S. Frolova, Dmitry S. Baev and Tatyana G. Tolstikova


DOI: 10.2174/1871523018666190426152049



Optimization of Microemulgel for Tizanidine Hydrochloride

, 2020; 19(2): 158 - 179

Swati Jagdale*, Sujata Brahmane and Anuruddha Chabukswar


DOI: 10.2174/1871523018666190308123100




Design and Development of Novel 2-(Morpholinyl)-N-substituted Phenylquinazolin-4-amines as Selective COX-II Inhibitor

, 2019; 18(1): 4 - 25

Bhushan R. Dravyakar*, Pramod B. Khedekar, Tabassum Khan, Atul P. Sherje, Kavit N. Patel and Vasanti Suvarna


DOI: 10.2174/1871523017666181022144053






Open Access Articles


Pro- and Anti-Inflammatory Cytokine Expression Levels in Macrophages; An Approach to Develop Indazolpyridin-methanones as Novel Inflammation Medication

, 2020; 19(4): 425 - 435

Manikandan Alagumuthu, Vanshika Srivastava, Manisha Shah, Sivakumar Arumugam, Mohandoss Sonaimuthu and Napoleon Ayyakannu Arumugam *




Synthesis and Biological Activity of a Bis-steroid-methanocyclobutanaphthalene- dione Derivative against Ischemia/Reperfusion Injury via Calcium Channel Activation

, 2020; 19(4): 393 - 412

Figueroa-Valverde Lauro*, Diaz-Cedillo Francisco, Rosas-Nexticapa Marcela*, Mateu-Armand Virginia, Garcimarero-Espino E. Alejandra, Lopez-Ramos Maria, Hau-Heredia Lenin, Borges-Ballote Yaritza and Cabrera-Tuz Jhair




In silico and in vitro Study of the Inhibitory Effect of Antiinflammatory Drug Betamethasone on Two Lipases

, 2020; 19(4): 387 - 392

Nia Samira*, Benarous Khedidja, Abdelalim Fatima Zahra, Chellali Khadidja Nour Elyakine and Yousfi Mohamed




New Anti-inflammatory Triterpene Esters and Glycosides from Alstonia scholaris

, 2020; 19(4): 370 - 386

Nighat Sultana*, Muhammad Saleem Qazi and Mustafa Kamal




Tegaserod for the Treatment of Irritable Bowel Syndrome

, 2020; 19(4): 342 - 369

Valentina Noemi Madia, Antonella Messore, Francesco Saccoliti, Valeria Tudino, Alessandro De Leo, Daniela De Vita, Martina Bortolami, Luigi Scipione, Ivano Pindinello, Roberta Costi* and Roberto Di Santo




Omalizumab for the Treatment of Persistent Drug Induced Urticaria Elicited by Thienopyridines: A Case Report

, 2020; 19(3): 335 - 339

Gianfranco Calogiuri*, Eustachio Nettis, Alessandro Mandurino-Mirizzi, Elisabetta Di Leo, Luigi Macchia, Caterina Foti, Angelo Vacca and Nicholas G. Kounis





Analgesic and Anti-inflammatory Effects of Caryocar brasiliense

, 2020; 19(3): 313 - 322

Armando Jorge Junior, Maicon Matos Leitão, Laura Priscila Toledo Bernal, Elisângela dos Santos, Ângela Midori Kuraoka-Oliveira, Priscila Justi, Eliana Janet Sanjinez Argandoña and Cândida Aparecida Leite Kassuya*




Comparative Evaluation of Colon Cancer Specific Antigen-2 Test and Chromocolonoscopy for Early Detection of Egyptian Patients with Colorectal Cancer

, 2020; 19(3): 302 - 312

Marwa Elhossary, Nehah Hawash, Rehab Badawi, Mohamed Yousef, Sherief Abd-Elsalam*, Mohammed Elhendawy, Rania Wasfy, Sabry Abou-Saif, Amal ElBendary and Saber Ismail




Evaluation of the Anti-Inflammatory Activities of Diclofenac Sodium, Prednisolone and Atorvastatin in Combination with Ascorbic Acid

, 2020; 19(3): 291 - 301

Tanvir Ahmed, Sabrina Rahman Archie, Asef Faruk, Fabliha Ahmed Chowdhury, Abdullah Al Shoyaib and Chowdhury Rafiqul Ahsan*




Design, Synthesis and Pharmacological Evaluation of Gastro- Protective Anti-inflammatory Analgesic Agents based on Dual Oxidative Stress / Cyclooxygenase Inhibition

, 2020; 19(3): 268 - 290

Monika Gaba, Sarbjot Singh, Chander Mohan, Richa Dhingra , Monika Chauhan , Priyanka Rana and Neelima Dhingra*




Betulinic Acid-Azaprostanoid Hybrids: Synthesis and Pharmacological Evaluation as Anti-inflammatory Agents

, 2020; 19(3): 254 - 267

Tatyana S. Khlebnicova*, Yuri A. Piven, Fedor A. Lakhvich, Iryna V. Sorokina, Tatiana S. Frolova, Dmitry S. Baev and Tatyana G. Tolstikova




Phycocyanin Extracted from Oscillatoria minima Shows Antimicrobial, Algicidal, and Antiradical Activities: In silico and In vitro Analysis

, 2020; 19(3): 240 - 253

Vaishali C. Venugopal*, Abhimanyu Thakur, Latha K. Chennabasappa, Gaurav Mishra, Kunal Singh, Parth Rathee and Anjali Ranjan




Psoralen Derivatives: Recent Advances of Synthetic Strategy and Pharmacological Properties

, 2020; 19(3): 222 - 239

Joazaizulfazli Jamalis*, Faten Syahira Mohamed Yusof, Subhash Chander, Roswanira Abd. Wahab, Deepak P. Bhagwat, Murugesan Sankaranarayanan, Faisal Almalki and Taibi Ben Hadda*





Most Cited Articles

Research Article

Mitigation of radiation-induced pneumonitis and lung fibrosis using alpha-lipoic acid and resveratrol

, 2020; 19(2): 149-157.

Rasoul Azmoonfar, Peyman Amini, Rasoul Yahyapour, Abolhassan Rezaeyan, Alireza Tavassoli, Elahe Motevaseli, Ehsan Khodamoradi, Dheyauldeen Shabeeb, Ahmed E. Musa and Masoud Najafi*


DOI: 10.2174/1871523018666190319144020



Review Article

Human toxocara infection: Allergy and immune responses

, 2019; 18(2): 82-90.

Mohammad Zibaei*, Zahra Shayesteh*, Najmeh Moradi and Saeed Bahadory


DOI: 10.2174/1871523018666181210115840


Research Article

Protection from radiation-induced damage in rat’s ileum and colon by combined regimens of melatonin and metformin: A histopathological study

, 2020; 19(2): 180-189.

Masoud Najafi , Mohsen Cheki*, Gholamreza Hassanzadeh, Peyman Amini, Dheyauldeen Shabeeb and Ahmed E. Musa


DOI: 10.2174/1871523018666190718161928



Research Article

Amyloid A in serum and ascitic fluid as a novel diagnostic marker of spontaneous bacterial peritonitis

, 2020; 19(2): 140-148.

Rehab Badawi, Muhammad N. Asghar, Sherief Abd-Elsalam*, Samah A. Elshweikh, Tamer Haydara, Sherein M. Alnabawy, Mahmoud Elkadeem, Walaa ElKhalawany, Samah Soliman, Reham Elkhouly, Shimaa Soliman, Mona Watany, Mai Khalif and Asem Elfert


DOI: 10.2174/1871523018666190401154447


Research Article

Systemic lupus erythematosus: Symptoms and signs at initial presentations

, 2019; 18(2): 142-150.

Abdel Masieh Metry, Issa Al Salmi*, Farida Al Balushi, Mohammed Abdalla Yousef, Faisal Al Ismaili, Alan Hola and Suad Hannawi


DOI: 10.2174/1871523018666181128161828


Review Article (Mini-Review)

Tegaserod for the treatment of irritable bowel syndrome

, 2020; 19(4): 342-369.

Valentina Noemi Madia, Antonella Messore, Francesco Saccoliti, Valeria Tudino, Alessandro De Leo, Daniela De Vita, Martina Bortolami, Luigi Scipione, Ivano Pindinello, Roberta Costi* and Roberto Di Santo


DOI: 10.2174/1871523018666190911121306



Research Article

Screening of NO inhibitor release activity from soft coral extracts origin Palu Bay, Central Sulawesi, Indonesia

, 2019; 18(2): 126-141.

Wendy Alexander Tanod*, Uun Yanuhar, Maftuch, Masteria Yunovilsa Putra and Yenny Risjani*


DOI: 10.2174/1871523018666190222115034


Review Article

Psoralen derivatives: Recent advances of synthetic strategy and pharmacological properties

, 2020; 19(3): 222-239.

Joazaizulfazli Jamalis*, Faten Syahira Mohamed Yusof, Subhash Chander, Roswanira Abd. Wahab, Deepak P. Bhagwat, Murugesan Sankaranarayanan, Faisal Almalki and Taibi Ben Hadda*


DOI: 10.2174/1871523018666190625170802


Research Article

Mitigation of radiation-induced gastrointestinal system injury using resveratrol or alpha-lipoic acid: A pilot histopathological study

, 2020; 19(4): 413-424.

Bagher Farhood, Gholamreza Hassanzadeh, Peyman Amini, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Ehsan Khodamoradi, Mehran Mohseni, Akbar Aliasgharzadeh, Habiballah Moradi and Masoud Najafi*


DOI: 10.2174/1871523018666191111124028


Research Article

Evaluation of the anti-inflammatory activities of diclofenac sodium, prednisolone and atorvastatin in combination with ascorbic acid

, 2020; 19(3): 291-301.

Tanvir Ahmed, Sabrina Rahman Archie, Asef Faruk, Fabliha Ahmed Chowdhury, Abdullah Al Shoyaib and Chowdhury Rafiqul Ahsan*


DOI: 10.2174/1871523018666190514112048


Review Article

Progranulin regulates inflammation and tumor

, 2020; 19(2): 88-102.

Chunxiao Liu, Jiayi Li, Wenjing Shi, Liujia Zhang, Shuang Liu, Yingcong Lian, Shujuan Liang and Hongyan Wang*


DOI: 10.2174/1871523018666190724124214


Research Article

Antioxidant effects of oleuropein on hydrogen peroxide-induced neuronal stress-an in vitro study

, 2020; 19(1): 74-84.

Altug Kucukgul*, Mehmet M. Isgor, Vesile Duzguner, Meryem N. Atabay and Azime Kucukgul


DOI: 10.2174/1871523018666190201145824



Most Accessed Articles




Covid-19: Urgent Call to Action

, 2021; 20(2): 118-122.

Amal A. Mohamed, Omnia I. Tantawi, Lamiaa A. Fathalla, Dalia M. Abd El-Hassib, Naglaa El-Toukhy R. El-Toukhy, Wafaa Salah, Mahmoud Elkadeem, Omnia Ezzat and Sherief Abd-Elsalam*


DOI: 10.2174/1871523019666201202092859


C1 Inhibitor Administration Reduces Local Inflammation and Capillary Leakage, Without Affecting Long-term Wound Healing Parameters, in a Pig Burn Wound Model

, 2021; 20(2): 150-160.

Halil Ibrahim Korkmaz*, Magda M.W. Ulrich, Wessel N. Van Wieringen, Hatice Doǧan, Marcel Vlig, Reindert W. Emmens, Klaas W. Meyer, Paul Sinnige, Sacha Zeerleder, Diana Wouters, Marieke S. Van Ham, Paul P.M. Van Zuijlen, Paul A.J. Krijnen and Hans W.M. Niessen


DOI: 10.2174/1871523019666200702101513


Modulation of Proinflammatory Bacteria- and Lipid-Coupled Intracellular Signaling Pathways in a Transwell Triple Co-Culture Model by Commensal Bifidobacterium Animalis R101-8

, 2021; 20(2): 161-181.

Darab Ghadimi*, Annegret Nielsen, Mohamed Farghaly Yoness Hassan, Regina Fölster-Holst, Michael Ebsen, Sven Olaf Frahm, Christoph Röcken, Michael de Vrese and Knut J. Heller


DOI: 10.2174/1871523019999201029115618




Anti-Nociceptive and Anti-Inflammatory Effects of Stem Bark Extract of Ficus Capensis Thunb (Moraceae) by Bioactivity Fractionation

, 2021; 20(2): 206-218.

Oluwaseyi K. Wakeel*, Abraham I. Abe, Oluropo B. Awosan, Mokaila K. Olapade, Temitope J. Olatoyan-Layonu, Olugbenga A. Olowe and Oluwaseyi A. Adeyeba


DOI: 10.2174/1871523019666200825194616


Predictive and Prognostic Value of Ascitic Fluid Mannose Binding Lectin in Patients with Spontaneous Bacterial Peritonitis

, 2021; 20(2): 196-200.

Amal A. Mohamed, Mohamed Abdelhamid, Naglaa El-Toukhy, Ahmed Sabry, Rania A. Khattab, Dalia Ali El-damasy, Abeer Ahmed, Mahmoud Elkadeem and Sherief Abd-Elsalam*


DOI: 10.2174/1871523019666200617132513


Effects of Kolaviron on Pneumonia-like Infection Induced in Albino Wistar Rats

, 2021; 20(2): 219-227.

Ogechukwu Calista Dozie-Nwakile, Nwakile Calistus Dozie, Uchendu Ikenna Kingsley*, Okonkwo Francis Catherine and Onyemelukwe Ngozi Felicia


DOI: 10.2174/1871523019666200915085729


Pro- and Anti-Inflammatory Cytokine Expression Levels in Macrophages; An Approach to Develop Indazolpyridin-methanones as Novel Inflammation Medication

, 2020; 19(4): 425-435.

Manikandan Alagumuthu, Vanshika Srivastava, Manisha Shah, Sivakumar Arumugam, Mohandoss Sonaimuthu and Napoleon Ayyakannu Arumugam *


DOI: 10.2174/1871523019666191226104724



Molecular Modelling, Synthesis and Evaluation of Flavone and Flavanone Scaffolds as Anti-inflammatory Agents

, 2021; 20(1): 20-38.

Natarajan Kiruthiga*, Manikandan Alagumuthu, Chellappa Selvinthanuja, Kulandaivel Srinivasan and Thangavel Sivakumar


DOI: 10.2174/1871523019666200102112017





Editor-in-Chief

graphic
Claudiu T. Supuran
(83932 citations)
Neurofarba Department
University of Florence
Florence
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents was launched in 2002 and later renamed in 2006 as Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry.

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