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Central Nervous System Agents in Medicinal Chemistry

Formerly: Current Medicinal Chemistry - Central Nervous System Agents

Volume 22, 3 Issues, 2022
ISSN: 1875-6166 (Online)
ISSN: 1871-5249 (Print)
This journal supports open access

Aims & Scope

Central Nervous System Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new central nervous system agents.

Containing a series of in-depth/mini reviews, original research articles, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics, Central Nervous System Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in the field.

Central Nervous System Agents in Medicinal Chemistry

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Volume 21

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Number 3






Research Article

Targeting cAMP-pathway in Regeneration-competent Cells of Nervous Tissue: Potential to Create a Novel Drug for Treatment of Ethanol-induced Neurodegeneration

, 21(3): 172 - 180

Gleb Nikolaevich Zyuz’kov*, Larisa Arkad`evna, Tatyana Yur`evna Polykova, Elena Vladislavovna Simanina and Larisa Alexandrovna Stavrova


DOI: 10.2174/1871524921666210907102847


Research Article

Effect of Methadone Maintenance on Expression of BDNF and CREB Genes in Brain VTA of Male Morphine Treated Rats

, 21(3): 181 - 186

Marzieh Rezai, Mohammad Reza Hajizadeh, Mehdi Mahmoodi, Seyedeh Atekeh Torabizadeh and Mojgan Noroozi Karimabad*


DOI: 10.2174/1871524922666211223153555




Articles Ahead of Print


In silico Study of Acetylcholinesterase and Beta-secretase Inhibitors: Potential Multitarget Anti-Alzheimer’s Agents


Daniel Castro da Costa, Hueldem Ronam Cristo Teixeira, Raí Campos Silva, Isaque Antonio Galindo Francischini, Carlos Henrique Tomich de Paula da Silva and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524922666220517110606
View Abstract








Promising Effects of Naringenin and Melatonin against Hepatic Encephalopathy Impairments Induced by Bile Duct Ligation in Male Rats


Elahe Karami Raviz, Fatemeh Noormand, Ali Sharifzadeh Kermani, Ali Galedari, Khadijeh Esmaeilpour, Marzieh Maneshian, Taj Pari Kalantaripour, Shahriar Dabiri and Majid Asadi- Shekaari*


DOI: 10.2174/1871524922666220314123052
View Abstract View on PubMed


Abstracts Ahead of Print

Formulation Development and in-vitro Evaluation of Escitalopram Fast Dissolving Tablets


Vishal Bhatia, Ashwani K. Dhingra*, Rameshwar Dass, Bhawna Chopra and Kumar Guarve


DOI: 10.2174/1871524922666220624113719
View Abstract


Are Patients with Schizophrenia reporting reliably their Cannabis Use? An African cross-sectional study


Ismail Rammouz*, Mohamed Merzouki, Sara Bouri, Aalouane Rachid, Amine Bout and Saïd Boujraf


DOI: 10.2174/1871524922666220620150033
View Abstract


Novel molecular targets and mechanisms for neuroprotective modulation in neurodegenerative disorders


Aala Azari, Amin Goodarzi, Behrouz Jafarkhani, Mohammad Eghbali, Zohreh Karimi, Seyed Sajad Hosseini Balef and Hamid Irannejad*


DOI: 10.2174/1871524922666220616092132
View Abstract



Erythroxylum cuneatum prevented cellular adaptation in morphine-induced neuroblastoma cells


Noor Azuin Suliman, Mohamad Aris Mohd Moklas*, Che Norma Mat Taib, Mohamad Taufik Hidayat Baharuldin and Samaila Musa Chiroma


DOI: 10.2174/1871524922666220516151121
View Abstract





Published Contents

Editor's Choice

Influence of Inosine on Cerebral Hemodynamics in Space Motion Sickness in Experimental Animals

, 2021; 21(2): 93 - 103

Asie N. Useinova , Vitalii B. Kaliberdenko , Igor D. Sapegin , Shanmugaraj Kulanthaivel *, Michael V. Shterenshis , Maria I. Dmitriyevskaya and Keerthanaa Balasundaram


DOI: 10.2174/1871524921666210428111827





Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review

, 2019; 19(2): 75 - 99

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524919666190502105855



A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis

, 2019; 19(1): 8 - 14

Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*


DOI: 10.2174/1871524918666181017152053



Classification (Agonist/Antagonist) and Regression “Structure-Activity” Models of Drug Interaction with 5-HT6

, 2018; 18(3): 213 - 221

Oleg A. Raevsky, Veniamin Y. Grigorev, Alexander V. Yarkov, Daniel E. Polianczyk, Vadim V. Tarasov, Elena V. Bovina, Elena N. Bryzhakina, John C. Dearden, Marco Avila-Rodriguez and Gjumrakch Aliev*


DOI: 10.2174/1871524918666180827100437




Astrocyte`s RAGE: More Than Just a Question of Mood

, 2018; 18(1): 39 - 48

Rodrigo E. Gonzalez-Reyes* and Maria G. Rubiano


DOI: 10.2174/1871524916999160505105121





Open Access Articles

The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report

, 2020; 20(3): 218 - 225

Arturo S. Herrera, Narasimha M. Beeraka, Luis Fernando T. Solis, Liudmila M. Mikhaleva, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*





Most Cited Articles


Review Article

Acrylamide induced toxicity and the propensity of phytochemicals in amelioration: A review

, 2019; 19(2): 100-113.

Shinomol George Kunnel*, Sunitha Subramanya, Pankaj Satapathy, Ishtapran Sahoo and Farhan Zameer*


DOI: 10.2174/1871524919666190207160236


Review Article

Berberine: A plant-derived alkaloid with therapeutic potential to combat Alzheimer’s disease

, 2019; 19(3): 154-170.

Anurag K. Singh, Santosh K. Singh, Manmath K. Nandi, Gaurav Mishra, Anand Maurya, Arati Rai, Gopal K. Rai, Rajendra Awasthi*, Bhupesh Sharma and Giriraj T. Kulkarni


DOI: 10.2174/1871524919666190820160053


Review Article

Antioxidant effect of flavonoids present in euterpe oleracea martius and neurodegenerative diseases: A literature review

, 2019; 19(2): 75-99.

Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*


DOI: 10.2174/1871524919666190502105855






Research Article

An evaluation of the effects of pyridoxal phosphate in chlorpromazineinduced parkinsonism using mice

, 2020; 20(1): 13-25.

Anthony T. Olofinnade, Tolulope M. Onaolapo, Samad Oladimeji, Adetunji M. Fatoki, Covenant I. Balogun, Adejoke Y. Onaolapo* and Olakunle J. Onaolapo


DOI: 10.2174/1871524920666200120142508



Research Article

A novel highly selective cannabinoid CB2 agonist reduces in vitro growth and TGF-beta release of human glial cell tumors

, 2019; 19(3): 206-214.

Chiara Cioni, Maristella Tassi, Giuseppe Marotta, Claudia Mugnaini, Federico Corelli* and Pasquale Annunziata*


DOI: 10.2174/1871524919666190923154351


Review Article

Noradrenergic regulation of hippocampus-dependent memory

, 2019; 19(3): 187-196.

Peter V. Nguyen and Steven A. Connor*


DOI: 10.2174/1871524919666190719163632



Letter

Cholinesterase inhibitory activities of selected halogenated thiophene chalcones

, 2019; 19(1): 67-71.

Della G.T. Parambi, Fakhrya Aljoufi, Vikneswaran Murugaiyah, Githa E. Mathew, Sanal Dev, Balasubramanain Lakshminarayanan, Omnia M. Hendawy and Bijo Mathew*


DOI: 10.2174/1871524918666181119114016




Most Accessed Articles

Influence of Inosine on Cerebral Hemodynamics in Space Motion Sickness in Experimental Animals

, 2021; 21(2): 93-103.

Asie N. Useinova , Vitalii B. Kaliberdenko , Igor D. Sapegin , Shanmugaraj Kulanthaivel *, Michael V. Shterenshis , Maria I. Dmitriyevskaya and Keerthanaa Balasundaram


DOI: 10.2174/1871524921666210428111827




Statistical Review of the Suicide Attempts Rates Committed on Polish Railway Tracks between the Years 2013-2016

, 2021; 21(2): 85-92.

Marta Makara-Studzinska, Adam Czabański, Katarzyna Gronowska, Jerzy Leszek, Elizaveta V. Mikhaylenko, Marco F. Avila-Rodriguez, Cristian Muresanu, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/1871524921666210204220621


Protective Effect of Capparis spinosa Extract against Focal Cerebral Ischemia-reperfusion Injury in Rats

, 2021; 21(2): 148-153.

Hassan Rakhshandeh, Samira Asgharzade, Mohammad Bagher Khorrami and Fatemeh Forouzanfar *


DOI: 10.2174/1871524921666210625112356



Anti-convulsive Effect of Thiamine and Melatonin Combination in Mice: Involvement of Oxidative Stress

, 2021; 21(2): 125-129.

Ehsan Dehdashtian, Azam Hosseinzadeh, Karim Hemati, Mohammad Yahya Karimi, Iman Fatemi and Saeed Mehrzadi*


DOI: 10.2174/1871524921666210623161212



The Neuroprotective Properties, Functions, and Roles of Cannabis sativa in Selected Diseases Related to the Nervous System

, 2021; 21(1): 20-38.

Onesimus Mahdi, Mohamad T.H. Baharuldin, Nurul Huda M. Nor, Samaila M. Chiroma, Saravanan Jagadeesan and Mohamad A.M. Moklas*


DOI: 10.2174/1871524921666210127110028







The Efficacy of Melanin Precursor QIAPI 1© Against Age-related Macular Degeneration (AMD): A Case Report

, 2020; 20(3): 218-225.

Arturo S. Herrera, Narasimha M. Beeraka, Luis Fernando T. Solis, Liudmila M. Mikhaleva, Siva G. Somasundaram, Cecil E. Kirkland and Gjumrakch Aliev*


DOI: 10.2174/1871524920666201109152951




Editor-in-Chief

graphic
Ramon Cacabelos
International Center of Neuroscience and Genomic Medicine
EuroEspes Biomedical Research Center
Corunna
(Spain)
Biography
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