Central Nervous System Agents in Medicinal Chemistry
Formerly: Current Medicinal Chemistry - Central Nervous System Agents
Volume 19, 3 Issues, 2019
ISSN: 1875-6166 (Online)
ISSN: 1871-5249 (Print)
This journal supports open access
ISSN: 1875-6166 (Online)
ISSN: 1871-5249 (Print)
This journal supports open access
Aims & Scope
Central Nervous System Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of new central nervous system agents.
Containing a series of in-depth/mini reviews, original research articles, drug clinical trial studies and guest edited thematic issues written by leaders in the field covering a range of current topics, Central Nervous System Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in the field.
Central Nervous System Agents in Medicinal Chemistry
,Volume 19
-Number 1
Biography Open Access
Meet Our Section Editor
Preface Open Access
Preface
Perspective Open Access
Unraveling the Structural Requirements of Chalcone Chemistry Towards Monoamine Oxidase Inhibition
, 19(1): 6 - 7Bijo Mathew
DOI: 10.2174/1871524919666190131160122
Unraveling the Structural Requirements of Chalcone Chemistry Towards Monoamine Oxidase Inhibition
Review Article
A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis
, 19(1): 8 - 14Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*
DOI: 10.2174/1871524918666181017152053
A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis
Research Article
Human Suicide, Modern Diagnosis Assistance and Magic Bullet Discovery
, 19(1): 15 - 23Da-Yong Lu*, Peng-Peng Zhu, Hong-Ying Wu, Nagendra Sastry Yarla, Bin Xu, Jian Ding, Ajit Varki and Ting-Ren Lu
DOI: 10.2174/1871524919666190115130655
Human Suicide, Modern Diagnosis Assistance and Magic Bullet Discovery
Research Article
Computational Study on the Role of γ-Synuclein in Inhibiting the α-Synuclein Aggregation
, 19(1): 24 - 30Airy Sanjeev and Venkata S.K. Mattaparthi*
DOI: 10.2174/1871524918666181012160439
Computational Study on the Role of γ-Synuclein in Inhibiting the α-Synuclein Aggregation
Research Article
Design, Synthesis, Anticonvulsant Activity, Preclinical Study and Pharmacokinetic Performance of N-{[3-(4-chlorophenyl)-4-oxo-3, 4-dihydroquinazolin- 2-yl] methyl}, 2-[(2-isopropyl-5-methyl) 1-cyclo Hexylidene] Hydrazinecarboxamide
, 19(1): 31 - 45Meena K. Yadav and Laxmi Tripathi *
DOI: 10.2174/1871524919666181122124012
Design, Synthesis, Anticonvulsant Activity, Preclinical Study and Pharmacokinetic Performance of N-{[3-(4-chlorophenyl)-4-oxo-3, 4-dihydroquinazolin- 2-yl] methyl}, 2-[(2-isopropyl-5-methyl) 1-cyclo Hexylidene] Hydrazinecarboxamide
Research Article
Development and Characterization of Nasal Delivery of Selegiline Hydrochloride Loaded Nanolipid Carriers for the Management of Parkinson’s Disease
, 19(1): 46 - 56Neeraj Mishra*, Sawarni Sharma, Rahul Deshmukh, Anoop Kumar and Ruchika Sharma
DOI: 10.2174/1871524919666181126124846
Development and Characterization of Nasal Delivery of Selegiline Hydrochloride Loaded Nanolipid Carriers for the Management of Parkinson’s Disease
Articles Ahead of Print
Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review
Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*
View Abstract
Pharmacological Approach of Pistacia Vera Fruit to Assess Learning and Memory Potential in Chemically- Induced Memory Impairment in Mice
Satyam Singh, Dharamveer and Mayank Kulshreshtha*
View Abstract View on PubMed
Glacial Acetic Acid Catalyzed Synthesis, Physicochemical and Biological Evaluation of Benzodiazepines as Potent CNS Agents
Vipin Kumar*, Shweta Verma and Sushil Kumar
View Abstract View on PubMed
Natural Compounds and Drug Discovery. Can Cnidarian Venoms Play a Role?
Gian Luigi Mariottini* and I. Darren Grice
View Abstract View on PubMed
Acrylamide Induced Toxicity and the Propensity of Phytochemicals in Amelioration: A Review
Shinomol George K.*, Sunitha S., Pankaj Satapathy, Ishtapran Sahoo and Farhan Zameer
View Abstract View on PubMed
Abstracts Ahead of Print
There are currently no Abstracts Ahead of Print available for this journal.
Published Contents
- Central Nervous System Agents in Medicinal Chemistry , Volume 19, 2019
- Central Nervous System Agents in Medicinal Chemistry , Volume 18, 2018
- Central Nervous System Agents in Medicinal Chemistry , Volume 17, 2017
- Central Nervous System Agents in Medicinal Chemistry , Volume 16, 2016
- Central Nervous System Agents in Medicinal Chemistry , Volume 15, 2015
- Central Nervous System Agents in Medicinal Chemistry , Volume 14, 2014
- Central Nervous System Agents in Medicinal Chemistry , Volume 13, 2013
- Central Nervous System Agents in Medicinal Chemistry , Volume 12, 2012
- Central Nervous System Agents in Medicinal Chemistry , Volume 11, 2011
- Central Nervous System Agents in Medicinal Chemistry , Volume 10, 2010
- Central Nervous System Agents in Medicinal Chemistry , Volume 9, 2009
- Central Nervous System Agents in Medicinal Chemistry , Volume 8, 2008
- Central Nervous System Agents in Medicinal Chemistry , Volume 7, 2007
- Central Nervous System Agents in Medicinal Chemistry , Volume 6, 2006
- Current Medicinal Chemistry - Central Nervous System Agents, Volume 5, 2005
- Current Medicinal Chemistry - Central Nervous System Agents, Volume 4, 2004
- Current Medicinal Chemistry - Central Nervous System Agents, Volume 3, 2003
- Current Medicinal Chemistry - Central Nervous System Agents, Volume 2, 2002
- Current Medicinal Chemistry - Central Nervous System Agents, Volume 1, 2001
Editor's Choice
A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis
, 2019; 19(1): 8 - 14Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*
DOI: 10.2174/1871524918666181017152053
Classification (Agonist/Antagonist) and Regression “Structure-Activity” Models of Drug Interaction with 5-HT6
, 2018; 18(3): 213 - 221Oleg A. Raevsky, Veniamin Y. Grigorev, Alexander V. Yarkov, Daniel E. Polianczyk, Vadim V. Tarasov, Elena V. Bovina, Elena N. Bryzhakina, John C. Dearden, Marco Avila-Rodriguez and Gjumrakch Aliev*
DOI: 10.2174/1871524918666180827100437
Nitrocatechol Derivatives of Chalcone as Inhibitors of Monoamine Oxidase and Catechol-O-Methyltransferase
, 2018; 18(2): 115 - 127Idalet Engelbrecht, Jacobus P. Petzer and Anel Petzer*
DOI: 10.2174/1871524918666180426125714
Astrocyte´s RAGE: More Than Just a Question of Mood
, 2018; 18(1): 39 - 48Rodrigo E. Gonzalez-Reyes* and Maria G. Rubiano
DOI: 10.2174/1871524916999160505105121
Synthesis, Computational and Pharmacological Evaluation of N-(2-benzoyl- 4-chlorophenyl)-2-(4-(Substituted Phenyl) Piperazin-1-yl) Acetamides as CNS Agents
, 2017; 17(3): 229 - 238Shweta Verma*, Surendra Kumar and Sushil Kumar
DOI: 10.2174/1871524917666170321103951
Alpha-7 Nicotinic Receptors in Nervous System Disorders: From Function to Therapeutic Perspectives
, 2017; 17(2): 100 - 108Antonella De Jaco, Laura Bernardini, Jessica Rosati and Ada Maria Tata*
DOI: 10.2174/1871524916666160729111446
Psychomotor Seizure Screening and in vitro Neuroprotection Assay of Hydrazones Derived from 2-Acetyl Thiophene
, 2017; 17(1): 51 - 57Bijo Mathew, Githa E. Mathew, Jerad Suresh, Mohammed Jaseel, D. Usman, P. N. Shiva Subramanyan, Kallivalappil F. Safna and Jobin K. Vilapurathu
DOI: 10.2174/1871524915999151028111728
Schiff Bases of Benzothiazol-2-ylamine and Thiazolo[5,4-b] pyridin-2-ylamine as Anticonvulsants: Synthesis, Characterization and Toxicity Profiling*
, 2016; 16(3): 240 - 248Rashmi Shukla, Ajeet P. Singh, Pankaj K. Sonar, Mudita Mishra and Shailendra K. Saraf
DOI: 10.2174/1871524916666160428110728
Opening New Scenarios for Human MAO Inhibitors
, 2016; 16(2): 98 - 104Celeste D Monte, Melissa D'Ascenzio, Paolo Guglielmi, Veronica Mancini and Simone Carradori
DOI: 10.2174/1871524915666150831141705
Computational Analysis and Functional Prediction of Ubiquitin Hypothetical Protein: A Possible Target in Parkinson Disease
, 2016; 16(1): 4 - 11Laline Barragan-Osorio, Gustavo Giraldo, Carlos J. Almeciga-Diaz, Gjumrakch Aliev, George E. Barreto and Janneth Gonzalez
DOI: 10.2174/1871524915666150722120605
Open Access Articles
Antioxidant Effect of Flavonoids Present in Euterpe oleracea Martius and Neurodegenerative Diseases: A Literature Review
, 2019; 19: 1 - 25 (E-Pub Ahead of Print)Nayana Keyla Seabra de Oliveira*, Marcos Rafael Silva Almeida, Franco Márcio Maciel Pontes, Mariana Pegrucci Barcelos, Carlos Henrique Tomich de Paula da Silva, Joaquín María Campos Rosa, Rodrigo Alves Soares Cruz and Lorane Izabel da Silva Hage-Melim*
Brain and Quantum Dots: Benefits of Nanotechnology for Healthy and Diseased Brain
, 2018; 18(3): 193 - 205Yuri N. Utkin*
Schiff Bases of Benzothiazol-2-ylamine and Thiazolo[5,4-b] pyridin-2-ylamine as Anticonvulsants: Synthesis, Characterization and Toxicity Profiling*
, 2016; 16(3): 240 - 248Rashmi Shukla, Ajeet P. Singh, Pankaj K. Sonar, Mudita Mishra and Shailendra K. Saraf
Opening New Scenarios for Human MAO Inhibitors
, 2016; 16(2): 98 - 104Celeste D Monte, Melissa D'Ascenzio, Paolo Guglielmi, Veronica Mancini and Simone Carradori
Brain Senescence and Neuroprotective Dietary Components
, 2007; 7(2): 109 - 114Keiko Unno and Minoru Hoshino
Most Cited Articles
Research Article
Synthesis, molecular docking and evaluation of 3-{4-[2-amino-4-(Substitutedphenyl)-2h-[1, 3] oxazin/thiazin-6-yl} 2-phenyl-3h-quinazolin-4-one derivatives for their anticonvulsant activity
, 1 May 2018; 18(1): 63-73.Nimisha Jain, Jugnu Jaiswal, Ashish Pathak and Pradeep K. Singour*
DOI: 10.2174/1871524917666170104142033
Review Article
Recent findings in melatonin research and their relevance to the CNS
, 2018; 18(2): 102-114.Rudiger Hardeland*
DOI: 10.2174/1871524918666180531083944
Review Article
Brain and quantum dots: Benefits of nanotechnology for healthy and diseased brain
, 2018; 18(3): 193-205.Yuri N. Utkin*
DOI: 10.2174/1871524918666180813141512
Research Article
Neuromyelitis optica (NMO IgG+) and genetic susceptibility, potential ethnic influences
, 1 May 2018; 18(1): 4-7.Veronica R. Alonso, Jose de Jesus Flores Rivera, Yamel R. Garci, Julio Granados, Thalia Sanchez, Lourdes Mena-Hernandez and Teresa Corona*
DOI: 10.2174/1871524916666160229115047
Review Article
Epigenetics in multiple sclerosis: Molecular mechanisms and dietary intervention
, 1 May 2018; 18(1): 8-15.Yamel Rito, Ivan Torre-Villalvazo, Jose Flores, Veronica Rivas and Teresa Corona*
DOI: 10.2174/1871524916666160226131842
Perspective
Unraveling the structural requirements of chalcone chemistry towards monoamine oxidase inhibition
, 2019; 19(1): 6-7.Bijo Mathew
DOI: 10.2174/1871524919666190131160122
Research Article
Design, synthesis, anticonvulsant activity, preclinical study and pharmacokinetic performance of n-{[3-(4-chlorophenyl)-4-oxo-3, 4-dihydroquinazolin- 2-yl] methyl}, 2-[(2-isopropyl-5-methyl) 1-cyclo hexylidene] hydrazinecarboxamide
, 2019; 19(1): 31-45.Meena K. Yadav and Laxmi Tripathi *
DOI: 10.2174/1871524919666181122124012
Review Article
A novel non-invasive effective method for potential treatment of degenerative disc disease: A hypothesis
, 2019; 19(1): 8-14.Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*
DOI: 10.2174/1871524918666181017152053
Research Article
Bacopa monnieri supplements offset paraquat-induced behavioral phenotype and brain oxidative pathways in mice
, 2019; 19(1): 57-66.Gokul Krishna*, Ravikumar Hosamani and Muralidhara
DOI: 10.2174/1871524919666190115125900
Research Article
RETRACTED: Human suicide, modern diagnosis assistance and magic bullet discovery
, 2019; 19(1): 15-23.Da-Yong Lu*, Peng-Peng Zhu, Hong-Ying Wu, Nagendra Sastry Yarla, Bin Xu, Jian Ding, Ajit Varki and Ting-Ren Lu
DOI: 10.2174/1871524919666190115130655
Research Article
Computational study on the role of γ-Synuclein in inhibiting the α-synuclein aggregation
, 2019; 19(1): 24-30.Airy Sanjeev and Venkata S.K. Mattaparthi*
DOI: 10.2174/1871524918666181012160439
Research Article
Development and characterization of nasal delivery of selegiline hydrochloride loaded nanolipid carriers for the management of parkinson’s disease
, 2019; 19(1): 46-56.Neeraj Mishra*, Sawarni Sharma, Rahul Deshmukh, Anoop Kumar and Ruchika Sharma
DOI: 10.2174/1871524919666181126124846
Letter
Cholinesterase inhibitory activities of selected halogenated thiophene chalcones
, 2019; 19(1): 67-71.Della G.T. Parambi, Fakhrya Aljoufi, Vikneswaran Murugaiyah, Githa E. Mathew, Sanal Dev, Balasubramanain Lakshminarayanan, Omnia M. Hendawy and Bijo Mathew*
DOI: 10.2174/1871524918666181119114016
Review Article
Recent finding in repair of the peripheral nerve lesions using pharmacological agents: Common methods for evaluating the repair process
, 2018; 18(3): 161-172.Dheyauldeen Shabeeb, Masoud Najafi, Mansor Keshavarz, Ahmed Eleojo Musa, Gholamreza Hassanzadeh, Mohammed Reza Hadian and Alireza Shirazi*
DOI: 10.2174/1871524918666180830101953
Most Accessed Articles
Epigenetics in Multiple Sclerosis: Molecular Mechanisms and Dietary Intervention
, 2018; 18(1): 8-15.Yamel Rito, Ivan Torre-Villalvazo, Jose Flores, Veronica Rivas and Teresa Corona*
DOI: 10.2174/1871524916666160226131842
A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis
, 2019; 19(1): 8-14.Siva G. Somasundaram, Cristian Muresanu, Pamela Schield, Alfiya Makhmutovа, Elena V. Bovina, Vladimir P. Fisenko, Nusrat F. Hasanov and Gjumrakch Aliev*
DOI: 10.2174/1871524918666181017152053
Recent Finding in Repair of the Peripheral Nerve Lesions Using Pharmacological Agents: Common Methods for Evaluating the Repair Process
, 2018; 18(3): 161-172.Dheyauldeen Shabeeb, Masoud Najafi, Mansor Keshavarz, Ahmed Eleojo Musa, Gholamreza Hassanzadeh, Mohammed Reza Hadian and Alireza Shirazi*
DOI: 10.2174/1871524918666180830101953
Computational Study on the Role of γ-Synuclein in Inhibiting the α-Synuclein Aggregation
, 2019; 19(1): 24-30.Airy Sanjeev and Venkata S.K. Mattaparthi*
DOI: 10.2174/1871524918666181012160439
Neuropharmacological Profile of Gamma-Decanolactone on Chemically-induced Seizure in Mice
, 2018; 18(3): 222-227.Pricila Pfluger, Vanessa Rodrigues Coelho, Gabriela Gregory Regner, Lucas Lima da Silva, Karina Martinez, Alan Fonseca, Cassiana Macagnan Viau and Patricia Pereira*
DOI: 10.2174/1871524918666180611103802
Unraveling the Structural Requirements of Chalcone Chemistry Towards Monoamine Oxidase Inhibition
, 2019; 19(1): 6-7.Bijo Mathew
DOI: 10.2174/1871524919666190131160122
Malaria, Antimalaria Drugs, Drug/Parasite Interactions, and the Brain: A Review of Impacts on Behaviour, Neurochemistry and Structure
, 2018; 18(3): 173-192.Onaolapo Adejoke Yetunde, Onaolapo Olakunle James* and Adeyeba Oluwaseyi Adegboyega
DOI: 10.2174/1871524918666180717111520
Human Suicide Risk and Treatment Study
, 2018; 18(3): 206-212.Da-Yong Lu*, Peng-Peng Zhu, Hong-Ying Wu, Nagendra Sastry Yarla, Bin Xu and Ting-Ren Lu
DOI: 10.2174/1871524918666180817093015
Neuromyelitis Optica (NMO IgG+) and Genetic Susceptibility, Potential Ethnic Influences
, 2018; 18(1): 4-7.Veronica R. Alonso, Jose de Jesus Flores Rivera, Yamel R. Garci, Julio Granados, Thalia Sanchez, Lourdes Mena-Hernandez and Teresa Corona*
DOI: 10.2174/1871524916666160229115047
Development and Characterization of Nasal Delivery of Selegiline Hydrochloride Loaded Nanolipid Carriers for the Management of Parkinson’s Disease
, 2019; 19(1): 46-56.Neeraj Mishra*, Sawarni Sharma, Rahul Deshmukh, Anoop Kumar and Ruchika Sharma
DOI: 10.2174/1871524919666181126124846
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Co-Editors
G.S. Hamilton (USA)
G. Aliev (USA)
G. Aliev (USA)
About the Journal
For Authors
For Librarians & Readers
Journal History
Current Medicinal Chemistry - Central Nervous System Agents was launched in 2001 and later renamed in 2006 as Central Nervous System Agents in Medicinal Chemistry.
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