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Clinical Cancer Drugs (Discontinued)

ISSN: 2212-6988 (Online)
ISSN: 2212-697X (Print)
This journal supports open access

Aims & Scope

Clinical Cancer Drugs publishes original research, full-length reviews/ mini reviews, and thematic issues in all core areas of translational and clinical cancer drug research.

The journal publishes pre-clinical and clinical studies on the development of new anti-cancer agents. Clinical studies of new reported anti-cancer drugs include Phase 1–IV clinical trial studies, their designs, research methodologies, and analyses. The journal is essential reading for clinical oncologists, toxicologists, medicinal chemists, and pharmacologists.

Clinical Cancer Drugs

,

Volume 8

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Number 2




Research Article

Hydroxychloroquine (HCQ) Exhibits Better Binding to the Main Protease (M<sup>pro</sup>) Compared to Spike Protein (S protein) of SARS-CoV-2: An In-silico Analysis

, 8(2): 106 - 115

Deepa R. Bandi, SubbaRao V. Tulimilli, Durai Ananda Kumar T., Chandi Kumari Chitturi, Anjalidevi S. Bettadapura, Suma M. Natraj and SubbaRao V. Madhunapantula *


DOI: 10.2174/2212697X08666211210103711


Research Article

Weight Gain and Loss in Cancer Patients Undergoing Chemotherapy: Importance of Dose Adjustment

, 8(2): 116 - 121

Maria Ayanny de Lima Fernandes*, Andreza Tallyne de Aguiar Silva, Iago Dillion Lima Cavalcanti*, Adrya Lúcia Peres Bezerra de Medeiros, Lígia Maria de Oliveira Lima and Tâmara Kelly de Castro Gomes


DOI: 10.2174/2212697X08666211210105329


Research Article

Inonotus obliquus Aqueous Extract Suppresses Carbon Tetrachloride-induced Hepatic Injury through Modulation of Antioxidant Enzyme System and Anti-inflammatory Mechanism

, 8(2): 122 - 136

Pir Mohammad Ishfaq, Anjali Mishra, Shivani Mishra, Zaved Ahmad, Shovanlal Gayen, Subodh Kumar Jain, Swati Tripathi and Siddhartha Kumar Mishra*


DOI: 10.2174/2212697X08666211130130119


Research Article



Research Article

Idarubicin and Ara-C Treatment Associated with Fungal Infection in Acute Leukemia Patients with Febrile Neutropenia

, 8(2): 146 - 151

Chinadol Wanitpongpun, Nattiya Teawtrakul, Theerin Lanamtieng, Kanchana Chansung, Chittima Sirijeerachai, Worakamol Amampai and Kittisak Sawanyawisuth*


DOI: 10.2174/2212697X08666211108095152



Articles Ahead of Print

Neurotoxicity of Cisplatin as Monotherapy or Combined Chemotherapy in Cancer Treatment


André Nunes Volpini, Igor José de Souza Marques and Iago Dillion Lima Cavalcanti*


DOI: 10.2174/2212697X09666220629161535
View Abstract


Differential Proliferative and Cytotoxic Effect of Selected Components of Essential Oils on Human Glioblastoma Cells


Sumbla Sheikh*, Alexander Sturzu, Hubert Kalbacher , Thomas Nägele , Ulrike Ernemann and Stefan Heckl


DOI: 10.2174/2212697X08666211210104609
View Abstract


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Editor's Choice

Alsevirone-NF Reduces Serum Testosterone and Inhibits Prostate Cancer Xenograft Growth in Balb/c Nude Mice

, 2020; 7(2): 113 - 118

Vadim S. Pokrovsky*, Vladimir A. Zolottsev, Alexandra S. Latysheva, Vasiliy A. Kudinov, Natalia Yu Anisimova, R.L.M. Almanza, Olga Yu Alekseeva, Konstantin K. Baskaev, Galina B. Smirnova, Yulia A. Borisova and Olga M. Ipatova


DOI: 10.2174/2212697X07999200511082225






Arachidonic Acid Induces the Migration of MDA-MB-231 Cells by Activating Raft-associated Leukotriene B4 Receptors

, 2018; 5(1): 28 - 41

Atasi De Chatterjee, Debarshi Roy, Priscilla Guevara, Rituraj Pal, Mahesh Narayan, Sukla Roychowdhury and Siddhartha Das*


DOI: 10.2174/2212697X05666180418145601



Prevalence of Neuropathy Associated With Bortezomib: A Retrospective Study

, 2017; 4(1): 69 - 72

Pulivarthi Swaroopa, Mathew Josy, Ehresmann Kirsten and Gurram Murali Krishna*


DOI: 10.2174/2212697X03666161128102453





Inhibition of Autophagy by Targeting ATG4B: Promises and Challenges of An Emerging Anti-cancer Strategy

, 2015; 2(1): 61 - 70

Kelly Lien, Michelle Rocha, Elisa Tran, Van C. Hoang, Annabelle Chow and Urban Emmenegger


DOI: 10.2174/2212697X02666150331202809



Impaired Autophagy Mediates Resistance to Low-Dose Metronomic Cyclophosphamide Chemotherapy

, 2014; 1(2): 116 - 126

Annabelle Chow, Giulio Francia, Andrew Kouri, Christina Lee, John M. Ebos, Robert S. Kerbel and Urban Emmenegger


DOI: 10.2174/2212697X01666131218235200



Open Access Articles

Idarubicin and Ara-C Treatment Associated with Fungal Infection in Acute Leukemia Patients with Febrile Neutropenia

, 2021; 8(2): 146 - 151

Chinadol Wanitpongpun, Nattiya Teawtrakul, Theerin Lanamtieng, Kanchana Chansung, Chittima Sirijeerachai, Worakamol Amampai and Kittisak Sawanyawisuth*




A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies

, 2020; 7(2): 125 - 132

Karen A. Gelmon*, Christian Kollmannsberger, Stephen Chia, Anna V. Tinker, Teresa Mitchell, Stephen Lam, Teresa Joshi, David Kwok, John Ostrem, Simon Sutcliffe and Daniel J. Renouf





Novel Antibody Therapeutics Targeting Mesothelin In Solid Tumors

, 2016; 3(2): 76 - 86

Xiao-Yan Zhao, Babu Subramanyam, Nenad Sarapa, Sven Golfier and Harald Dinter





The Importance of Lamivudine Therapy in Liver Cirrhosis Patients Related HBV with Advanced Hepatocellular Carcinoma Receiving Hepatic Arterial Infusion Chemotherapy

, 2015; 2(2): 112 - 118

Koichi Momiyama, Hidenari Nagai, Yu Ogino, Takanori Mukouzu, Daigo Matsui, Michio Kogame, Teppei Matsui, Noritaka Wakui, Mie Shinohara, Yoshinori Igarashi and Yasukiyo Sumino






Most Cited Articles

Upfront DPD Deficiency Detection to Secure 5-FU Administration: Part 1 – Where Do We Stand?

, 2017; 4(2): 74-81.

Manon Launay, Joseph Ciccolini*, Anne Rodallec, Claire Fournel, Florence Duffaud, Sebastien Salas and Bruno Lacarelle


DOI: 10.2174/2212697X04666170531080625


The PI3K/AKT/mTOR-Signal Transduction Pathway as Drug Target in Triple-Negative Breast Cancer

, 2017; 4(1): 47-58.

Jens C. Hahne*, Jorg B. Engel, Arnd Honig, Susanne R. Meyer, Domenico Zito, Andrea Lampis and Nicola Valeri


DOI: 10.2174/2212697X04666170321112629


Intra-arterial Temozolomide, Osmotic Blood-brain Barrier Disruption and Radiotherapy in a Rat F98-Glioma Model

, 2017; 4(2): 135-144.

Annie I. Drapeau, Marie-Belle Poirier, Guru-Swamy Madugundu, J. Richard Wagner and David Fortin*


DOI: 10.2174/2212697X04666170727152212


Pharmacokinetic Markers of 5-Fluorouracil Toxicity in Clinical Trials and Real World

, 2017; 4(2): 82-92.

Antonello Di Paolo*, Marzia Del Re, Elena Arrigoni, Teresa Di Desidero, Eleonora Rofi, Romano Danesi and Guido Bocci


DOI: 10.2174/2212697X04666170817124625



Most Accessed Articles





Alsevirone-NF Reduces Serum Testosterone and Inhibits Prostate Cancer Xenograft Growth in Balb/c Nude Mice

, 2020; 7(2): 113-118.

Vadim S. Pokrovsky*, Vladimir A. Zolottsev, Alexandra S. Latysheva, Vasiliy A. Kudinov, Natalia Yu Anisimova, R.L.M. Almanza, Olga Yu Alekseeva, Konstantin K. Baskaev, Galina B. Smirnova, Yulia A. Borisova and Olga M. Ipatova


DOI: 10.2174/2212697X07999200511082225


Does the Oxazolidinone Derivatives Constitute a Functional Approach for Cancer Therapy?

, 2020; 7(2): 95-106.

Eduardo Augusto Vasconcelos de Freitas Ramalho*, Marina Galdino da Rocha Pitta, Hernando de Barros Siqueira Neto and Ivan da Rocha Pitta


DOI: 10.2174/2212697X07999200807210936


A Phase I Study of OMN54 (Aneustat™) in Patients with Advanced Malignancies

, 2020; 7(2): 125-132.

Karen A. Gelmon*, Christian Kollmannsberger, Stephen Chia, Anna V. Tinker, Teresa Mitchell, Stephen Lam, Teresa Joshi, David Kwok, John Ostrem, Simon Sutcliffe and Daniel J. Renouf


DOI: 10.2174/1574893615999200601130946



Melatonin Induces Apoptosis and Inhibits the Proliferation of Cancer Cells via Reactive Oxygen Species-mediated MAPK and mTOR Pathways

, 2020; 7(1): 44-56.

Reena Kasi, Pei Ling Yeo, Ng. Khuen Yen, Rhun Yian Koh, Gnanajothy Ponnudurai, Yee Lian Tiong and Soi Moi Chye*


DOI: 10.2174/2212697X06666191116151114




Complexity in Clinical Trials: Blind Spots, Misleading Criteria, Winners and Losers

, 2020; 7(1): 3-15.

Gang Yuan, Lishi Wang, Jing Li, Helin Feng, Jiafu Ji, Weikuan Gu* and Baoen Shan*


DOI: 10.2174/2212697X06666191021125423


Metformin Treatment Sensitizes Human Laryngeal Cancer Cell Line Hep- 2 to 5-Fluorouracil

, 2020; 7(1): 16-24.

Neslisah Barlak, Fatma Sanli, Ozel Capik, Elanur Tuysuz, Elanur Aydın Karatas, Hasan Turkez and Omer Faruk Karatas*


DOI: 10.2174/2212697X06666190906165309



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