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Current Molecular Pharmacology

Volume 13, 4 Issues, 2020
ISSN: 1874-4702 (Online)
ISSN: 1874-4672 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications to drug action. An additional focus will be the way in which normal biological function is illuminated by knowledge of the action of drugs at the cellular and molecular level. The journal publishes full-length/mini reviews, original research articles and thematic issues on molecular pharmacology.

Current Molecular Pharmacology is an essential journal for every scientist who is involved in drug design and discovery, target identification, target validation, preclinical and clinical development of drugs therapeutically useful in human disease.

Current Molecular Pharmacology

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Volume 13

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Number 3



Review Article



Review Article

FAT10: Function and Relationship with Cancer

, 13(3): 182 - 191

Senfeng Xiang, Xuejing Shao, Ji Cao, Bo Yang, Qiaojun He* and Meidan Ying*


DOI: 10.2174/1874467212666191113130312


Review Article



Research Article



Research Article

Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

, 13(3): 216 - 223

Tatiana V. Vyunova*, Lioudmila A. Andreeva, Konstantin V. Shevchenko, Vladimir V. Grigoriev, Vladimir A. Palyulin, Mstislav I. Lavrov, Ekaterina V. Bondarenko, Elena E. Kalashnikova and Nikolay F. Myasoedov


DOI: 10.2174/1874467213666200303140834


Research Article



Research Article



Research Article

Evaluation of the Anti-Tumor Activity of Niclosamide Nanoliposomes Against Colon Carcinoma

, 13(3): 245 - 250

Mahdi Hatamipour, Mahmoud R. Jaafari, Amir A. Momtazi-Borojeni, Mahin Ramezani and Amirhossein Sahebkar*


DOI: 10.2174/1874467212666190821142721


Current Molecular Pharmacology, Volume 13 (2020) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

H3K4 Methylation Status and Lysine Specific Methyltransferase KMT2C Expression Correlate with Prognosis in Lung Adenocarcinoma


Pinelopi Bosgana, Sophia Nikou, Foteinos-Ioannis Dimitrakopoulos, Souzana Logotheti, Vasiliki Tzelepi, Charalambos Kalophonos, Vasiliki Bravou, Eleni Kourea, Fotios Sampsonas* and Vassiliki Zolota*


DOI: 10.2174/1874467213999200831130739
View Abstract View on PubMed








Quercetin Inhibits AQP1 Translocation in High-glucose-cultured SRA01/04 Cells Through PI3K/Akt/mTOR Pathway


Linlin He, Nan Zhang, Lei Wang, Lei Du, Chengcheng Li, Yuan Li, Xizhi Li, Xia Zhu, Qian Lu and Xiaoxing Yin*


DOI: 10.2174/1874467213666200908120501
View Abstract View on PubMed



Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway


Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao*, Li-Chun Zhao and Shilin Yang


DOI: 10.2174/1874467213666200611141337
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice


Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

, 2020; 13(3): 216 - 223

Tatiana V. Vyunova*, Lioudmila A. Andreeva, Konstantin V. Shevchenko, Vladimir V. Grigoriev, Vladimir A. Palyulin, Mstislav I. Lavrov, Ekaterina V. Bondarenko, Elena E. Kalashnikova and Nikolay F. Myasoedov


DOI: 10.2174/1874467213666200303140834



Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis

, 2020; 13(2): 150 - 172

Samira Bahrami, Bahram Kazemi*, Hakimeh Zali, Peter C. Black, Abbas Basiri, Mojgan Bandehpour, Mehdi Hedayati and Amirhossein Sahebkar


DOI: 10.2174/1874467212666191016124935






Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*


DOI: 10.2174/1874467212666190215112915



Convergence of Canonical and Non-Canonical Wnt Signal: Differential Kat3 Coactivator Usage

, 2019; 12(3): 167 - 183

Keane K.Y. Lai*, Cu Nguyen, Kyung-Soon Lee, Albert Lee, David P. Lin, Jia-Ling Teo and Michael Kahn*


DOI: 10.2174/1874467212666190304121131



Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone

, 2019; 12(2): 139 - 146

Vishal J. Patel, Amit A. Joharapurkar*, Samadhan G. Kshirsagar, Brijesh K. Sutariya, Maulik S. Patel, Rajesh H. Bahekar and Mukul R. Jain


DOI: 10.2174/1874467212666190212112402




Open Access Articles

Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats

, 2020; 13: 1 - 8 (E-Pub Ahead of Print)

Nobuo Izumo, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, Yasuo Watanabe and Takayuki Manabe*




Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway

, 2020; 13: 1 - 11 (E-Pub Ahead of Print)

Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao*, Li-Chun Zhao and Shilin Yang




New Insights in Cannabinoid Receptor Structure and Signaling

, 2019; 12(3): 239 - 248

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*





Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*




Mitochondria-Targeted Drugs

, 2019; 12(3): 202 - 214

Roman A. Zinovkin* and Andrey A. Zamyatnin*




A Contemporary Overview of PPARα/γ Dual Agonists for the Management of Diabetic Dyslipidemia

, 2019; 12(3): 195 - 201

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar




Pharmacokinetic and Pharmacodynamic Aspects of Peyote and Mescaline: Clinical and Forensic Repercussions

, 2019; 12(3): 184 - 194

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva




Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316 - 325

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*





Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures

, 2017; 10(4): 334 - 344

Andrew S. Dore, Andrea Bortolato, Kaspar Hollenstein, Robert K.Y. Cheng, Randy J. Read and Fiona H. Marshall*






Pharmacology of L-type Calcium Channels: Novel Drugs for Old Targets?

, 2015; 8(2): 110 - 122

Jorg Striessnig, Nadine J. Ortner and Alexandra Pinggera






Most Cited Articles

Review Article

NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy

, 2019; 12(1): 50-60.

Keywan Mortezaee, Nasser Hashemi Goradel, Peyman Amini, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi* and Bagher Farhood*


DOI: 10.2174/1874467211666181010154709


Review Article

Mitochondria-targeted drugs

, 2019; 12(3): 202-214.

Roman A. Zinovkin* and Andrey A. Zamyatnin*


DOI: 10.2174/1874467212666181127151059


Review Article

Mechanisms for radioprotection by melatonin; can it be used as a radiation countermeasure?

, 2019; 12(1): 2-11.

Peyman Amini, Hanifeh Mirtavoos-Mahyari, Elahe Motevaseli, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Mohsen Cheki, Bagher Farhood, Rasoul Yahyapour, Alireza Shirazi, Nouraddin Abdi Goushbolagh and Masoud Najafi*


DOI: 10.2174/1874467211666180802164449




Review Article

New insights in cannabinoid receptor structure and signaling

, 2019; 12(3): 239-248.

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*


DOI: 10.2174/1874467212666190215112036


Research Article

In-vitro pre-treatment of cancer cells with TGF-β1: A novel approach of tail vein lung cancer metastasis mouse model for anti-metastatic studies

, 2019; 12(4): 249-260.

Ghulam Jilany Khan*, Li Sun, Muhammad Abbas, Muhammad Naveed, Talha Jamshaid, Mirza Muhammad Faran Ashraf Baig and Shengtao Yuan*


DOI: 10.2174/1874467212666190306165703


Research Article

MiR-597 targeting 14-3-3σ enhances cellular invasion and EMT in nasopharyngeal carcinoma cells

, 2019; 12(2): 105-114.

Lisha Xie, Tao Jiang, Ailan Cheng, Ting Zhang, Pin Huang, Pei Li, Gebo Wen, Fanghong Lei, Yun Huang, Xia Tang, Jie Gong, Yunpeng Lin, Jianke Kuai* and Weiguo Huang*


DOI: 10.2174/1874467212666181218113930


Research Article

Synergistic effect of epigenetic inhibitors decitabine and suberoylanilide hydroxamic acid on colorectal cancer in vitro

, 2019; 12(4): 281-300.

Sonia Abou Najem, Ghada Khawaja, Mohammad Hassan Hodroj and Sandra Rizk*


DOI: 10.2174/1874467212666190313154531



Review Article

A contemporary overview of PPARα/γ dual agonists for the management of diabetic dyslipidemia

, 2019; 12(3): 195-201.

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar


DOI: 10.2174/1874467212666190111165015


Review Article

Kinase targets for mycolic acid biosynthesis in mycobacterium tuberculosis

, 2019; 12(1): 27-49.

Shahinda S.R. Alsayed, Chau C. Beh, Neil R. Foster, Alan D. Payne, Yu Yu and Hendra Gunosewoyo*


DOI: 10.2174/1874467211666181025141114



Review Article

Recent updates in the alzheimer’s disease etiopathology and possible treatment approaches: A narrative review of current clinical trials

, 2020; 13(4): 273-294.

Elahe Zarini-Gakiye, Javad Amini, Nima Sanadgol*, Gholamhassan Vaezi and Kazem Parivar


DOI: 10.2174/1874467213666200422090135




Most Accessed Articles

Temozolomide: Mechanisms of Action, Repair and Resistance

, 2012; 5(1): 102-114.

Jihong Zhang, Malcolm F.G. Stevens and Tracey D. Bradshaw


DOI: 10.2174/1874467211205010102



Mevalonate Pathway and Human Cancers

, 2017; 10(2): 77-85.

Seyedeh Zahra Bathaie, Mahboobeh Ashrafi, Mahshid Azizian and Fuyuhiko Tamanoi


DOI: 10.2174/1874467209666160112123205








Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis

, 2020; 13(2): 150-172.

Samira Bahrami, Bahram Kazemi*, Hakimeh Zali, Peter C. Black, Abbas Basiri, Mojgan Bandehpour, Mehdi Hedayati and Amirhossein Sahebkar


DOI: 10.2174/1874467212666191016124935



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