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Current Drug Targets

Volume 21, 16 Issues, 2020
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

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Volume 21

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Number 14



Biography   Open Access



Editorial   Open Access



Review Article (Mini-Review)

Free Fatty Acid Receptors as New Potential Targets in Colorectal Cancer

, 21(14): 1397 - 1404

Adrian Bartoszek, Jakub Fichna, Aleksandra Tarasiuk, Agata Binienda, Adam Fabisiak, Julia B. Krajewska, Paula Mosińska, Karolina Niewinna and Maciej Salaga*


DOI: 10.2174/1389450120666191112141901


Review Article (Mini-Review)



Review Article



Review Article



Review Article



Review Article

Exosomes in Inflammatory Bowel Disease: What Have We Learned So Far?

, 21(14): 1448 - 1455

Haichao Wang, Chen Ye, Yaling Wu, Pengyu Yang, Chunqiu Chen, Zhanju Liu and Xiaolei Wang*


DOI: 10.2174/1389450121666200428102330


Articles Ahead of Print

An Agathokakological Tale of Δ9-THC: Exploration of Possible Biological Targets


Bijo Mathew*, Seetha Harilal, Arafa Musa, Rajesh Kumar, Della Grace Thomas Parambi, Jobin Jose, Md. Sahab Uddin, Muhammad Ajmal Shah, Tapan Behl and Mazhuvancherry Kesavan Unnikrishnan


DOI: 10.2174/1389450121666201001123515
View Abstract View on PubMed




Robotic Surgery in Inflammatory Bowel Disease


Jacopo Crippa, Michele Carvello, Paulo Gustavo Kotze and Antonino Spinelli*


DOI: 10.2174/1389450121999200820125918
View Abstract



Targeting Host Cell Proteases to Prevent SARS-CoV-2 Invasion


Upinder Kaur, Sankha Shubhra Chakrabarti*, Bisweswar Ojha, Bhairav Kumar Pathak, Amit Singh, Luciano Saso and Sasanka Chakrabarti


DOI: 10.2174/1389450121666200924113243
View Abstract View on PubMed


Progress in Detection of Insomnia Sleep Disorder: A Comprehensive Review


Haroon Khan*, Md Belal Bin Heyat, Dakun Lai, Faijan Akhtar, M.A. Ansari, Asif Khan and Fahed Alkahtani


DOI: 10.2174/1389450121666201027125828
View Abstract


Anti-platelet drug loaded targeted technologies for the effective treatment of Atherothrombosis


Selvakumar Muruganantham, Venkateshwaran Krishnaswami, Shanmugarathinam Alagarsamy and Ruckmani Kandasamy*


DOI: 10.2174/1389450121666201027125303
View Abstract




Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice

Exosomes in Inflammatory Bowel Disease: What Have We Learned So Far?

, 2020; 21(14): 1448 - 1455

Haichao Wang, Chen Ye, Yaling Wu, Pengyu Yang, Chunqiu Chen, Zhanju Liu and Xiaolei Wang*


DOI: 10.2174/1389450121666200428102330



PD1/PD-L1 Axis in Uro-oncology

, 2020; 21(13): 1293 - 1300

Kerstin Junker*, Markus Eckstein, Michelangelo Fiorentino and Rodolfo Montironi


DOI: 10.2174/1389450121666200326123700



Anti-VEGF Treatment in Corneal Diseases

, 2020; 21(12): 1159 - 1180

Giuseppe Giannaccare, Marco Pellegrini, Cristina Bovone, Rossella Spena, Carlotta Senni, Vincenzo Scorcia and Massimo Busin*


DOI: 10.2174/1389450121666200319111710










Open Access Articles

Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20(16): 1695 - 1701

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino




Current Understanding of Group A Streptococcal Biofilms

, 2019; 20(9): 982 - 993

Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*








Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga





Most Cited Articles

Review Article

Cyclin-dependent kinase 2 in cellular senescence and cancer. A structural and functional review

, 2019; 20(7): 716-726.

Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *


DOI: 10.2174/1389450120666181204165344



Review Article

Celecoxib in cancer therapy and prevention - review

, 2019; 20(3): 302-315.

Natalia Tołoczko-Iwaniuk , Dorota Dziemiańczyk-Pakieła, Beata Klaudia Nowaszewska, Katarzyna Celińska-Janowicz and Wojciech Miltyk*


DOI: 10.2174/1389450119666180803121737



Review Article

CDK9 as an appealing target for therapeutic interventions

, 2019; 20(4): 453-464.

Shirin Eyvazi, Mohammad Saeid Hejazi, Homan Kahroba, Mozghan Abasi, Reza Eghdam Zamiri and Vahideh Tarhriz*


DOI: 10.2174/1389450119666181026152221



Review Article

A survey for predicting enzyme family classes using machine learning methods

, 2019; 20(5): 540-550.

Jiu-Xin Tan, Hao Lv, Fang Wang, Fu-Ying Dao, Wei Chen* and Hui Ding*


DOI: 10.2174/1389450119666181002143355



Review Article

High mobility group box-1 (HMGB1): A potential target in therapeutics

, 2019; 20(14): 1474-1485.

Eyaldeva C. Vijayakumar, Lokesh Kumar Bhatt* and Kedar S. Prabhavalkar


DOI: 10.2174/1389450120666190618125100


Review Article

Molecular aspects of melatonin treatment in tinnitus: A review

, 2019; 20(11): 1112-1128.

Azam Hosseinzadeh, Seyed Kamran Kamrava, Brian C.J. Moore, Russel J. Reiter, Habib Ghaznavi, Mahboobeh Kamali and Saeed Mehrzadi*


DOI: 10.2174/1389450120666190319162147


Review Article

Opportunities of bacterial cellulose to treat epithelial tissues

, 2019; 20(8): 808-822.

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch


DOI: 10.2174/1389450120666181129092144


Review Article

Advances in discovery of PDE10A inhibitors for CNS-related Disorders. Part 1: Overview of the chemical and biological research

, 2019; 20(1): 122-143.

Agnieszka Jankowska, Artur Świerczek, Elżbieta Wyska, Alicja Gawalska, Adam Bucki, Maciej Pawłowski and Grażyna Chłoń-Rzepa*


DOI: 10.2174/1389450119666180808105056



Review Article

Exosomes in therapy: Engineering, pharmacokinetics and future applications

, 2019; 20(1): 87-95.

Claudia Arenaccio, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Eleonora Olivetta and Maurizio Federico*


DOI: 10.2174/1389450119666180521100409




Most Accessed Articles






Edaravone May Prevent Ferroptosis in ALS

, 2020; 21(8): 776-780.

Snežana Spasić*, Aleksandra Nikolić-Kokić, Srđan Miletić, Zorana Oreščanin-Dušić, Mihajlo B. Spasić, Duško Blagojević and Zorica Stević


DOI: 10.2174/1389450121666200220123305


Targeting c-MET/HGF Signaling Pathway in Upper Gastrointestinal Cancers: Rationale and Progress

, 2014; 15(14): 1302-1311.

Sharareh Gholamin, Hamid Fiuji, Mina Maftouh, Reza Mirhafez, Fatemeh Homaei Shandiz and Amir Avan


DOI: 10.2174/1389450115666141107105456


Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

, 2020; 21(3): 258-278.

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*


DOI: 10.2174/1389450120666190821160730


The Anti-Inflammatory Potential of ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Evidence from Basic and Clinical Research

, 2017; 18(11): 1301-1313.

Thiago Ruiz Rodrigues Prestes, Natalia Pessoa Rocha, Aline Silva Miranda, Antônio Lúcio Teixeira and Ana Cristina Simoes-e-Silva*


DOI: 10.2174/1389450117666160727142401




Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
(USA)
View Full Editorial Board

COPE Compliant

Journal History

Current Drug Targets Journal was launched in 2000. Dr. Francis J. Castellino serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 2.63

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