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Current Drug Targets

Volume 21, 16 Issues, 2020
ISSN: 1873-5592 (Online)
ISSN: 1389-4501 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes.

Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication full-length/mini review articles and drug clinical trial studies.

As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.

Current Drug Targets

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Volume 21

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Number 8



Biography   Open Access



Review Article

A Comparative Review on Current and Future Drug Targets Against Bacteria & Malaria

, 21(8): 736 - 775

Usha K. Rout, A.S. Sanket, Brijesh S. Sisodia, Pradyumna K. Mohapatra, Sanghamitra Pati, Rajni Kant and Gaurav R. Dwivedi*


DOI: 10.2174/1389450121666200129103618


Review Article

Edaravone May Prevent Ferroptosis in ALS

, 21(8): 776 - 780

Snežana Spasić*, Aleksandra Nikolić-Kokić, Srđan Miletić, Zorana Oreščanin-Dušić, Mihajlo B. Spasić, Duško Blagojević and Zorica Stević


DOI: 10.2174/1389450121666200220123305


Review Article



Review Article



Review Article



Review Article



Current Drug Targets, Volume 21 (2020) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Current Drug Targets, Volume 21 (2020) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Application of Artificial Intelligence in Targeting Retinal Diseases


Francesco Saverio Sorrentino, Giuseppe Jurman, Katia De Nadai, Claudio Campa, Cesare Furlanello and Francesco Parmeggiani*


DOI: 10.2174/1389450121666200708120646
View Abstract



Fluoroquinolones: Blessings Or Curses


Priyanka Prakash Majalekar* and Pramodkumar Jaykumar Shirote


DOI: 10.2174/1389450121666200621193355
View Abstract View on PubMed


How can targeted therapy influence renal surgery for renal cell carcinoma?


Francesco Greco*, Michele Marchioni, Francesco Esperto, Rocco Papalia, Luigi Schips and Roberto M Scarpa


DOI: 10.2174/1389450121666200704150933
View Abstract


Nanomedicine in Pancreatic Cancer: A New Hope for Treatment.


Pablo Redruello, Gloria Perazzoli, Ana Cepero, Francisco Quiñonero, Cristina Mesas, Kevin Doello, Antonio Láinez-Ramos-Bossini, Mario Rivera-Izquierdo, Consolación Melguizo* and Jose Prados


DOI: 10.2174/1389450121666200703195229
View Abstract




Exosomes in Inflammatory Bowel Disease: What Have We Learned So Far?


Haichao Wang, Chen Ye, Yaling Wu, Pengyu Yang, Chunqiu Chen, Zhanju Liu and Xiaolei Wang*


DOI: 10.2174/1389450121666200428102330
View Abstract View on PubMed



Berberine Administration in Treatment of Colitis: A Review


Milad Ashrafizadeh, Masoud Najafi, Reza Mohammadinejad, Tahereh Farkhondeh and Saeed Samarghandian*


DOI: 10.2174/1389450121666200621193758
View Abstract View on PubMed


Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Editor's Choice






Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

, 2020; 21(3): 258 - 278

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*


DOI: 10.2174/1389450120666190821160730



Angiotensin Type 1 Receptor Blockers in Heart Failure

, 2020; 21(2): 125 - 131

Khuraijam Dhanachandra Singh* and Sadashiva S. Karnik*


DOI: 10.2174/1389450120666190821152000



Circulating Exosomes and Their Role in Stroke

, 2020; 21(1): 89 - 95

Reza Jafarzadeh-Esfehani, Mohammad Soudyab, Seyed Mostafa Parizadeh, Mohammad Ehsan Jaripoor, Payam Sasan Nejad, Mohammad Shariati and Ariane Sadr Nabavi*


DOI: 10.2174/1389450120666190821153557



Aptamers in Drug Design: An Emerging Weapon to Fight a Losing Battle

, 2019; 20(16): 1624 - 1635

Jobin Jose, Aaron Mathew Thomas, Darewin Mendonsa, Mohammad M. Al-Sanea, Md. Sahab Uddin, Della Grace Thomas Parambi, R Narayana Charyulu and Bijo Mathew*


DOI: 10.2174/1389450120666190729121747




Open Access Articles

Recognition of Plasminogen Activator Inhibitor Type 1 as the Primary Regulator of Fibrinolysis

, 2019; 20(16): 1695 - 1701

Tetsumei Urano*, Yuko Suzuki, Takayuki Iwaki, Hideto Sano, Naoki Honkura and Francis J. Castellino




Current Understanding of Group A Streptococcal Biofilms

, 2019; 20(9): 982 - 993

Heema K.N. Vyas, Emma-Jayne Proctor, Jason McArthur, Jody Gorman and Martina Sanderson-Smith*








Opportunities of Bacterial Cellulose to Treat Epithelial Tissues

, 2019; 20(8): 808 - 822

Irene Anton-Sales, Uwe Beekmann, Anna Laromaine*, Anna Roig* and Dana Kralisch





Blood Eosinophils as Biomarkers to Drive Treatment Choices in Asthma and COPD

, 2018; 19(16): 1882 - 1896

Konstantinos Kostikas, Caterina Brindicci and Francesco Patalano*




Current Status and Perspectives on Pharmacologic Therapy for Abdominal Aortic Aneurysm

, 2018; 19(11): 1265 - 1275

Koichi Yoshimura*, Noriyasu Morikage, Shizuka Nishino-Fujimoto, Akira Furutani, Bungo Shirasawa and Kimikazu Hamano





TXNIP in Metabolic Regulation: Physiological Role and Therapeutic Outlook

, 2017; 18(9): 1095 - 1103

Naif Mohammad Alhawiti, Saeed Al Mahri, Mohammad Azhar Aziz, Shuja Shafi Malik and Sameer Mohammad*






Structural and Functional Aspects of Class A Carbapenemases

, 2016; 17(9): 1006 - 1028

Thierry Naas, Laurent Dortet and Bogdan I. Iorga





Most Cited Articles

Review Article

Cyclin-dependent kinase 2 in cellular senescence and cancer. A structural and functional review

, 2019; 20(7): 716-726.

Priscylla Andrade Volkart, Gabriela Bitencourt-Ferreira, André Arigony Souto* and Walter Filgueira de Azevedo *


DOI: 10.2174/1389450120666181204165344


Review Article

CDK9 as an appealing target for therapeutic interventions

, 2019; 20(4): 453-464.

Shirin Eyvazi, Mohammad Saeid Hejazi, Homan Kahroba, Mozghan Abasi, Reza Eghdam Zamiri and Vahideh Tarhriz*


DOI: 10.2174/1389450119666181026152221




Review Article

Celecoxib in cancer therapy and prevention - review

, 2019; 20(3): 302-315.

Natalia Tołoczko-Iwaniuk , Dorota Dziemiańczyk-Pakieła, Beata Klaudia Nowaszewska, Katarzyna Celińska-Janowicz and Wojciech Miltyk*


DOI: 10.2174/1389450119666180803121737


Review Article

Exosomes in therapy: Engineering, pharmacokinetics and future applications

, 2019; 20(1): 87-95.

Claudia Arenaccio, Chiara Chiozzini, Flavia Ferrantelli, Patrizia Leone, Eleonora Olivetta and Maurizio Federico*


DOI: 10.2174/1389450119666180521100409


Review Article

High mobility group box-1 (HMGB1): A potential target in therapeutics

, 2019; 20(14): 1474-1485.

Eyaldeva C. Vijayakumar, Lokesh Kumar Bhatt* and Kedar S. Prabhavalkar


DOI: 10.2174/1389450120666190618125100



Review Article

Silicon quantum dots: Promising theranostic probes for the future

, 2019; 20(12): 1255-1263.

Vishnu Sankar Sivasankarapillai, Jobin Jose, Muhammad Salman Shanavas, Akash Marathakam, Md. Sahab Uddin and Bijo Mathew*


DOI: 10.2174/1389450120666190405152315



Review Article

A survey for predicting enzyme family classes using machine learning methods

, 2019; 20(5): 540-550.

Jiu-Xin Tan, Hao Lv, Fang Wang, Fu-Ying Dao, Wei Chen* and Hui Ding*


DOI: 10.2174/1389450119666181002143355


Review Article

Do the natural chemical compounds interact with the same targets of current pharmacotherapy for weight management?-A review

, 2019; 20(4): 399-411.

Shiqi Luo, George Binh Lenon*, Harsharn Gill, Heidi Yuen, Angela Wei Hong Yang, Andrew Hung and Linh Toan Nguyen


DOI: 10.2174/1389450119666180830125958


Review Article

Inhibition of RAGE axis signaling: A pharmacological challenge

, 2019; 20(3): 340-346.

Armando Rojas*, Miguel Morales, Ileana Gonzalez and Paulina Araya


DOI: 10.2174/1389450119666180820105956


Review Article

Advances in discovery of PDE10A inhibitors for CNS-related Disorders. Part 1: Overview of the chemical and biological research

, 2019; 20(1): 122-143.

Agnieszka Jankowska, Artur Świerczek, Elżbieta Wyska, Alicja Gawalska, Adam Bucki, Maciej Pawłowski and Grażyna Chłoń-Rzepa*


DOI: 10.2174/1389450119666180808105056




Most Accessed Articles


The Anti-Inflammatory Potential of ACE2/Angiotensin-(1-7)/Mas Receptor Axis: Evidence from Basic and Clinical Research

, 2017; 18(11): 1301-1313.

Thiago Ruiz Rodrigues Prestes, Natalia Pessoa Rocha, Aline Silva Miranda, Antônio Lúcio Teixeira and Ana Cristina Simoes-e-Silva*


DOI: 10.2174/1389450117666160727142401






Targeting Cancer Stem Cells Pathways for the Effective Treatment of Cancer

, 2020; 21(3): 258-278.

Ashish Ranjan Dwivedi, Amandeep Thakur, Vijay Kumar, Ira Skvortsova and Vinod Kumar*


DOI: 10.2174/1389450120666190821160730



Angiotensin Type 1 Receptor Blockers in Heart Failure

, 2020; 21(2): 125-131.

Khuraijam Dhanachandra Singh* and Sadashiva S. Karnik*


DOI: 10.2174/1389450120666190821152000




Editor-in-Chief

Francis J. Castellino
(14643 citations)
Kleiderer-Pezold Professor of Biochemistry
Director, W.M. Keck Center for Transgene Research
Dean Emeritus, College of Science
230 Raclin-Carmichael Hall, University of Notre Dame
Notre Dame, IN 46556
(USA)
View Full Editorial Board

Journal History

Current Drug Targets Journal was launched in 2000. Dr. Francis J. Castellino serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 2.63

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