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Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

,

Volume 28

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Number 2



Biography   Open Access



Review Article

Critical Review on the Chemical Aspects of Cannabidiol (CBD) and Harmonization of Computational Bioactivity Data

, 28(2): 213 - 237

Andrea Mastinu*, Giovanni Ribaudo, Alberto Ongaro, Sara Anna Bonini, Maurizio Memo and Alessandra Gianoncelli


DOI: 10.2174/0929867327666200210144847


Review Article

Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids

, 28(2): 238 - 252

Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela*, Jianbo Xiao and María P. Portillo


DOI: 10.2174/0929867326666191029112626


Review Article



Review Article



Review Article

Current Scenario and Future Prospect in the Management of COVID-19

, 28(2): 284 - 307

Pobitra Borah, Pran Kishore Deb*, Satyendra Deka, Katharigatta N. Venugopala, Vinayak Singh, Raghu Prasad Mailavaram, Kiran Kalia and Rakesh Kumar Tekade*


DOI: 10.2174/0929867327666200908113642


Review Article

Exosomes and Lung Cancer: Roles in Pathophysiology, Diagnosis and Therapeutic Applications

, 28(2): 308 - 328

Atefeh Amiri, Mohammad Hossein Pourhanifeh, Hamid Reza Mirzaei, Javid Sadri Nahand, Mohsen Moghoofei, Roxana Sahebnasagh, Hamed Mirzaei* and Michael R. Hamblin*


DOI: 10.2174/0929867327666200204141952


Review Article

Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy

, 28(2): 329 - 345

Shunqin Zhu, Qin Yu, Chunsong Huo, Yuanpeng Li, Linshen He, Botian Ran, Ji Chen, Yonghao Li and Wanhong Liu*


DOI: 10.2174/0929867327666200121124404


Articles Ahead of Print


The Hydroxamic Acids as a Potential Anticancer and Neuroprotective Agents


Margarita E. Neganova, Sergey G. Klochkov, Yulia R. Aleksandrova and Gjumrakch Aliev*


DOI: 10.2174/0929867328666201218123154
View Abstract






Na, K-ATPase as a biological target for gold(III) complexes: a theoretical and experimental approach


Aleksandra M. Bondžić, Dragana D. Vasić Anićijević, Goran V. Janjić, Ivana Zeković, Tatjana Momić, Ana Vujačić Nikezić and Vesna M. Vasić*


DOI: 10.2174/0929867328999210101233801
View Abstract


Research Domain Criteria (RDoC): A Perspective to Probe the Biological Background behind Treatment Efficacy in Depression


Marco Calabrò, Chiara Fabbri, Siegfried Kasper, Joseph Zohar, Daniel Souery, Stuart Montgomery, Diego Albani, Gianluigi Forloni, Panagiotis Ferentinos, Dan Rujescu, Julien Mendlewicz, Roberto Colombo, Diana De Ronchi, Alessandro Serretti* and Concetta Crisafulli


DOI: 10.2174/0929867328666210104104938
View Abstract


The therapeutic use of the zonulin inhibitor AT-1001 (Larazotide) for a variety of acute and chronic inflammatory diseases


Jacopo Troisi*, Giorgia Venutolo, Concetta Terracciano, Matteo Delli Carri, Simone Di Micco, Annamaria Landolfi and Alessio Fasano


DOI: 10.2174/0929867328666210104110053
View Abstract



Abstracts Ahead of Print

There are currently no Abstracts Ahead of Print available for this journal.

Published Contents

Open Access Articles

Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

, 2020; 27(42): 7234 - 7255

Soraia Fernandes*, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri and Giancarlo Forte*





Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints

, 2020; 27(37): 6356 - 6372

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*











Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm

, 2019; 26(11): 1979 - 1993

Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano and Zuzanna Drulis-Kawa*





Fighting Type-2 Diabetes: Present and Future Perspectives

, 2019; 26(10): 1891 - 1907

Cai-Guo Yu, Ying Fu, Yuan Fang, Ning Zhang, Rong-Xin Sun, Dong Zhao, Ying-Mei Feng* and Bao-Yu Zhang*




Untargeted Metabolomics Provides Insight into the Mechanisms Underlying Resistant Hypertension

, 2019; 26(1): 232 - 243

Renata Wawrzyniak, Arlette Yumba Mpanga, Wiktoria Struck-Lewicka, Marta Kordalewska, Katarzyna Polonis, Małgorzata Patejko, Monika Mironiuk, Anna Szyndler, Marzena Chrostowska, Michał Hoffmann, Ryszard T. Smoleński, Roman Kaliszan, Krzysztof Narkiewicz and Michał J. Markuszewski*




Metabolomic Heterogeneity of Urogenital Tract Cancers Analyzed by Complementary Chromatographic Techniques Coupled with Mass Spectrometry

, 2019; 26(1): 216 - 231

Arlette Yumba-Mpanga, Wiktoria Struck-Lewicka, Renata Wawrzyniak, Marcin Markuszewski, Marek Roslan, Roman Kaliszan and Michał Jan Markuszewski*





Most Cited Articles


Review Article

Osteoporosis: Current and emerging therapies targeted to immunological checkpoints

, 2020; 27(37): 6356-6372.

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*


DOI: 10.2174/0929867326666190730113123


General Review Article

Aptamer-based targeted drug delivery systems: Current potential and challenges

, 2020; 27(13): 2189-2219.

Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*


DOI: 10.2174/0929867325666181008142831


Review Article

Targeting N-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease

, 2020; 27(31): 5250-5272.

Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis Alberto Videla


DOI: 10.2174/0929867326666190410121716


Review Article

Antimicrobial capacity of plant polyphenols against gram-positive bacteria: A comprehensive review

, 2020; 27(15): 2576-2606.

Francisco Javier Álvarez-Martínez, Enrique Barrajón-Catalán*, José Antonio Encinar, Juan Carlos Rodríguez-Díaz and Vicente Micol


DOI: 10.2174/0929867325666181008115650


Review Article

Recent progress in histone deacetylase inhibitors as anticancer agents

, 2020; 27(15): 2449-2493.

Loredana Cappellacci*, Diego R. Perinelli, Filippo Maggi, Mario Grifantini and Riccardo Petrelli*


DOI: 10.2174/0929867325666181016163110


Review Article

Antiviral activities of human host defense peptides

, 2020; 27(9): 1420-1443.

David C. Brice and Gill Diamond*


DOI: 10.2174/0929867326666190805151654



Review Article

Structural basis for inhibition of enoyl-[acyl carrier protein] reductase (Inha) from mycobacterium tuberculosis

, 2020; 27(5): 745-759.

Maurício Boff de Ávila, Gabriela Bitencourt-Ferreira and Walter Filgueira de Azevedo*


DOI: 10.2174/0929867326666181203125229


Review Article

The role of diet related short-chain fatty acids in colorectal cancer metabolism and survival: Prevention and therapeutic implications

, 2020; 27(24): 4087-4108.

Sara Daniela Gomes, Cláudia Suellen Oliveira, João Azevedo-Silva, Marta R. Casanova, Judite Barreto, Helena Pereira, Susana R. Chaves, Lígia R. Rodrigues, Margarida Casal, Manuela Côrte-Real, Fatima Baltazar and Ana Preto*


DOI: 10.2174/0929867325666180530102050


General Review Article

The role of matrix gla protein (MGP) in vascular calcification

, 2020; 27(10): 1647-1660.

Geir Bjørklund*, Erik Svanberg, Maryam Dadar, David J. Card, Salvatore Chirumbolo, Dominic J. Harrington and Jan Aaseth


DOI: 10.2174/0929867325666180716104159


Review Article

Obesity and body composition in man and woman: Associated diseases and the new role of gut microbiota

, 2020; 27(2): 216-229.

Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Giuseppe Palma, Laura Di Renzo and Antonino De Lorenzo


DOI: 10.2174/0929867326666190326113607


General Review Article

Role of microRNAs in chronic lymphocytic leukemia pathogenesis

, 2020; 27(2): 282-297.

Ehsan Javandoost, Ehsan Firoozi-Majd, Hosein Rostamian, Mohammad Khakpoor- Koosheh and Hamid Reza Mirzaei*


DOI: 10.2174/0929867326666190911114842


Review Article

Structural basis of drug recognition by human serum albumin

, 2020; 27(30): 4907-4931.

Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi


DOI: 10.2174/0929867326666190320105316


Review Article

Influence of oxidative stress on catalytic and non-glycolytic functions of glyceraldehyde-3-phosphate dehydrogenase

, 2020; 27(13): 2040-2058.

Vladimir I. Muronetz*, Aleksandra K. Melnikova, Luciano Saso and Elena V. Schmalhausen


DOI: 10.2174/0929867325666180530101057



Most Accessed Articles


Small-Molecule CSF1R Inhibitors as Anticancer Agents

, 2020; 27(23): 3944-3966.

Qiuju Xun, Zhen Wang, Xianglong Hu, Ke Ding* and Xiaoyun Lu*


DOI: 10.2174/1573394715666190618121649


Ferroptosis: A Novel Mechanism of Artemisinin and its Derivatives in Cancer Therapy

, 2021; 28(2): 329-345.

Shunqin Zhu, Qin Yu, Chunsong Huo, Yuanpeng Li, Linshen He, Botian Ran, Ji Chen, Yonghao Li and Wanhong Liu*


DOI: 10.2174/0929867327666200121124404


Sam Domains in Multiple Diseases

, 2020; 27(3): 450-476.

Marian Vincenzi, Flavia Anna Mercurio and Marilisa Leone*


DOI: 10.2174/0929867325666181009114445


Structural Basis of Drug Recognition by Human Serum Albumin

, 2020; 27(30): 4907-4931.

Loris Leboffe, Alessandra di Masi*, Fabio Polticelli, Viviana Trezza and Paolo Ascenzi


DOI: 10.2174/0929867326666190320105316


Current Scenario and Future Prospect in the Management of COVID-19

, 2021; 28(2): 284-307.

Pobitra Borah, Pran Kishore Deb*, Satyendra Deka, Katharigatta N. Venugopala, Vinayak Singh, Raghu Prasad Mailavaram, Kiran Kalia and Rakesh Kumar Tekade*


DOI: 10.2174/0929867327666200908113642


Acyclovir in the Treatment of Herpes Viruses – A Review

, 2020; 27(24): 4118-4137.

Katarzyna Kłysik, Aneta Pietraszek, Anna Karewicz and Maria Nowakowska*


DOI: 10.2174/0929867325666180309105519


Discovery and Development of the Oral Complement Factor D Inhibitor Danicopan (ACH-4471)

, 2020; 27(25): 4165-4180.

Jason A. Wiles, Manuel D. Galvan, Steven D. Podos, Michael Geffner and Mingjun Huang*


DOI: 10.2174/0929867326666191001130342


Effects of Pterostilbene on Diabetes, Liver Steatosis and Serum Lipids

, 2021; 28(2): 238-252.

Saioa Gómez-Zorita, Iñaki Milton-Laskíbar, Leixuri Aguirre, Alfredo Fernández-Quintela*, Jianbo Xiao and María P. Portillo


DOI: 10.2174/0929867326666191029112626


Monoclonal Antibodies Carried in Drug Delivery Nanosystems as a Strategy for Cancer Treatment

, 2021; 28(2): 401-418.

Amanda Letícia Polli Silvestre, Joáo Augusto Oshiro-Júnior*, Camila Garcia, Bruna Ortolani Turco, Joandra Maísa da Silva Leite, Bolivar Ponciano Goulart de Lima Damasceno, Jonas Corsino Maduro Soares and Marlus Chorilli*


DOI: 10.2174/0929867327666200121121409


Bioactive Secondary Metabolites from Endophytic Fungi

, 2020; 27(11): 1836-1854.

Elena Ancheeva, Georgios Daletos* and Peter Proksch*


DOI: 10.2174/0929867326666190916144709


Exosomes and Lung Cancer: Roles in Pathophysiology, Diagnosis and Therapeutic Applications

, 2021; 28(2): 308-328.

Atefeh Amiri, Mohammad Hossein Pourhanifeh, Hamid Reza Mirzaei, Javid Sadri Nahand, Mohsen Moghoofei, Roxana Sahebnasagh, Hamed Mirzaei* and Michael R. Hamblin*


DOI: 10.2174/0929867327666200204141952


Clinical and Translational Challenges in Thyroid Cancer

, 2020; 27(29): 4806-4822.

Jorge Hernando*, Javier Ros, Alvaro Arroyo and Jaume Capdevila


DOI: 10.2174/0929867327666200214125712


B7-H3 Immune Checkpoint Protein in Human Cancer

, 2020; 27(24): 4062-4086.

Karine Flem-Karlsen, Øystein Fodstad and Caroline E. Nunes-Xavier*


DOI: 10.2174/0929867326666190517115515




Editor-in-Chief

Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
Cambridge
(UK)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

Prof. John Gurdon
(UK)

Prof. Jean-Marie Lehn
(France)

Prof. Ferid Murad
(USA)

COPE Compliant

Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.
Scopus CiteScore Metrics: 3.61

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