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Current Medicinal Chemistry

Volume 28, 42 Issues, 2021
ISSN: 1875-533X (Online)
ISSN: 0929-8673 (Print)
This journal supports open access

Aims & Scope

Current Medicinal Chemistry covers all the latest and outstanding developments in medicinal chemistry and rational drug design. Each issue contains a series of timely in-depth/mini reviews and guest edited thematic issues written by leaders in the field covering a range of the current topics in medicinal chemistry. The journal also publishes reviews on recent patents. Current Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Current Medicinal Chemistry

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Volume 28

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Number 8



Biography   Open Access



Review Article

Biomarkers of Senescence During Aging as Possible Warnings to Use Preventive Measures

, 28(8): 1471 - 1488

Amin Gasmi, Salvatore Chirumbolo, Massimiliano Peana, Pavan Kumar Mujawdiya, Maryam Dadar, Alain Menzel and Geir Bjørklund*


DOI: 10.2174/0929867327999200917150652








Review Article

Curcumin: A Dietary Phytochemical for Targeting the Phenotype and Function of Dendritic Cells

, 28(8): 1549 - 1564

Kaveh Rahimi, Kambiz Hassanzadeh, Hashem Khanbabaei, Saeed M. Haftcheshmeh, Abbas Ahmadi, Esmael Izadpanah, Asadollah Mohammadi* and Amirhossein Sahebkar*


DOI: 10.2174/0929867327666200515101228






Current Medicinal Chemistry, Volume 28 (2021) - Number 12


This issue is in progress but contains articles that are final and fully citable.

Current Medicinal Chemistry, Volume 28 (2021) - Number 11


This issue is in progress but contains articles that are final and fully citable.

Current Medicinal Chemistry, Volume 28 (2021) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Current Medicinal Chemistry, Volume 28 (2021) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Using natural Compounds to Target KRAS Mutated Non-Small Cell Lung Cancer


Mahruba Sultana Niloy, Md. Salman Shakil, Md. Meharab Hassan Alif and Rhonda J. Rosengren*


DOI: 10.2174/0929867328666210301105856
View Abstract View on PubMed



Nucleoside Inhibitors of Coronaviruses


Anastasia A. Zenchenko*, Mikhail S. Drenichev and Sergey N. Mikhailov


DOI: 10.2174/0929867328666210208181724
View Abstract View on PubMed




MicroRNAs in the Management of Heart Failure


Aimilios Kalampogias, Gerasimos Siasos, Evangelos Oikonomou*, Konstantinos Mourouzis, Evanthia Bletsa, Panagiota K. Stampouloglou, Efstratios Katsianos, Konstantinos Vlasis, Georgios Marinos, Georgios Charalambous, Manolis Vavouranakis and Dimitris Tousoulis


DOI: 10.2174/0929867328666210218181441
View Abstract View on PubMed


Na, K-ATPase as a Biological Target for Gold(III) Complexes: A Theoretical and Experimental Approach


Aleksandra M. Bondžić, Dragana D. Vasić Anićijević, Goran V. Janjić, Ivana Zeković, Tatjana Momić, Ana Vujačić Nikezić and Vesna M. Vasić*


DOI: 10.2174/0929867328999210101233801
View Abstract View on PubMed


Novel Biomarkers for Lupus Nephritis in the “OMICS” Era


Raphael Dias, Ursula Gramiscelli Hasparyk, Monisi Lopes Peres, João Luiz Vieira Monteiro de Barros and Ana Cristina Simões e Silva*


DOI: 10.2174/0929867328666210212102438
View Abstract View on PubMed



Abstracts Ahead of Print








MiRNAs as Biomarkers in Hypertrophic Cardiomyopathy: Current State of the Art


Andreas Angelopoulos, Evangelos Oikonomou*, Georgia Vogiatzi, Alexios Antonopoulos, Sotirios Tsalamandris, Christos Georgakopoulos, Paraskevi Papanikolaou, George Lazaros, Georgios Charalambous, Gerasimos Siasos, Charalambos Vlachopoulos and Dimitris Tousoulis


DOI: 10.2174/0929867328666210405122703
View Abstract


Recent Advances in the Medicinal Chemistry of Phenothiazines. New Anticancer and Antiprotozoal Agents


Alonzo González-González, Lenci K. Vazquez-Jimenez, Alma D. Paz-González, María Laura Bolognesi and Gildardo Rivera*


DOI: 10.2174/0929867328666210405120330
View Abstract



Published Contents

Open Access Articles

Role of Alpha-Fetoprotein in Hepatocellular Carcinoma Drug Resistance

, 2021; 28(6): 1126 - 1142

Wei Li, Kun Liu, Yi Chen, Mingyue Zhu* and Mengsen Li*




Deep Learning in the Quest for Compound Nomination for Fighting COVID-19

, 2021; 28: 1 - 32 (E-Pub Ahead of Print)

Maria Mernea, Eliza. C. Martin, Andrei-José Petrescu* and Speranta Avram*




Tumor in 3D: In Vitro Complex Cellular Models to Improve Nanodrugs Cancer Therapy

, 2020; 27(42): 7234 - 7255

Soraia Fernandes*, Marco Cassani, Stefania Pagliari, Petr Filipensky, Francesca Cavalieri and Giancarlo Forte*





Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints

, 2020; 27(37): 6356 - 6372

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*











Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm

, 2019; 26(11): 1979 - 1993

Grzegorz Guła, Agata Dorotkiewicz-Jach, Kamila Korzekwa, Miguel A. Valvano and Zuzanna Drulis-Kawa*





Fighting Type-2 Diabetes: Present and Future Perspectives

, 2019; 26(10): 1891 - 1907

Cai-Guo Yu, Ying Fu, Yuan Fang, Ning Zhang, Rong-Xin Sun, Dong Zhao, Ying-Mei Feng* and Bao-Yu Zhang*





Most Cited Articles


Review Article

Osteoporosis: Current and emerging therapies targeted to immunological checkpoints

, 2020; 27(37): 6356-6372.

Massimo De Martinis, Maria Maddalena Sirufo and Lia Ginaldi*


DOI: 10.2174/0929867326666190730113123


General Review Article

Aptamer-based targeted drug delivery systems: Current potential and challenges

, 2020; 27(13): 2189-2219.

Fen He, Nachuan Wen, Daipeng Xiao, Jianhua Yan, Hongjie Xiong, Shundong Cai, Zhenbao Liu* and Yanfei Liu*


DOI: 10.2174/0929867325666181008142831


Review Article

Antimicrobial capacity of plant polyphenols against gram-positive bacteria: A comprehensive review

, 2020; 27(15): 2576-2606.

Francisco Javier Álvarez-Martínez, Enrique Barrajón-Catalán*, José Antonio Encinar, Juan Carlos Rodríguez-Díaz and Vicente Micol


DOI: 10.2174/0929867325666181008115650


Review Article

Antiviral activities of human host defense peptides

, 2020; 27(9): 1420-1443.

David C. Brice and Gill Diamond*


DOI: 10.2174/0929867326666190805151654


Review Article

Targeting N-3 polyunsaturated fatty acids in non-alcoholic fatty liver disease

, 2020; 27(31): 5250-5272.

Rodrigo Valenzuela*, Macarena Ortiz, María Catalina Hernández-Rodas, Francisca Echeverría and Luis Alberto Videla


DOI: 10.2174/0929867326666190410121716


Review Article

Recent progress in histone deacetylase inhibitors as anticancer agents

, 2020; 27(15): 2449-2493.

Loredana Cappellacci*, Diego R. Perinelli, Filippo Maggi, Mario Grifantini and Riccardo Petrelli*


DOI: 10.2174/0929867325666181016163110


Review Article

The role of diet related short-chain fatty acids in colorectal cancer metabolism and survival: Prevention and therapeutic implications

, 2020; 27(24): 4087-4108.

Sara Daniela Gomes, Cláudia Suellen Oliveira, João Azevedo-Silva, Marta R. Casanova, Judite Barreto, Helena Pereira, Susana R. Chaves, Lígia R. Rodrigues, Margarida Casal, Manuela Côrte-Real, Fatima Baltazar and Ana Preto*


DOI: 10.2174/0929867325666180530102050


General Review Article

The role of matrix gla protein (MGP) in vascular calcification

, 2020; 27(10): 1647-1660.

Geir Bjørklund*, Erik Svanberg, Maryam Dadar, David J. Card, Salvatore Chirumbolo, Dominic J. Harrington and Jan Aaseth


DOI: 10.2174/0929867325666180716104159



Review Article

Structural basis for inhibition of enoyl-[acyl carrier protein] reductase (Inha) from mycobacterium tuberculosis

, 2020; 27(5): 745-759.

Maurício Boff de Ávila, Gabriela Bitencourt-Ferreira and Walter Filgueira de Azevedo*


DOI: 10.2174/0929867326666181203125229


Review Article

Obesity and body composition in man and woman: Associated diseases and the new role of gut microbiota

, 2020; 27(2): 216-229.

Ennio Avolio*, Paola Gualtieri , Lorenzo Romano, Claudio Pecorella, Simona Ferraro, Giuseppe Palma, Laura Di Renzo and Antonino De Lorenzo


DOI: 10.2174/0929867326666190326113607


General Review Article

Role of microRNAs in chronic lymphocytic leukemia pathogenesis

, 2020; 27(2): 282-297.

Ehsan Javandoost, Ehsan Firoozi-Majd, Hosein Rostamian, Mohammad Khakpoor- Koosheh and Hamid Reza Mirzaei*


DOI: 10.2174/0929867326666190911114842


Review Article

Role of resveratrol in modulating microRNAs in human diseases: From cancer to inflammatory disorder

, 2021; 28(2): 360-376.

Atefeh Amiri, Maryam Mahjoubin-Tehran, Zatollah Asemi, Alimohammad Shafiee, Sarah Hajighadimi, Sanaz Moradizarmehri, Hamid Reza Mirzaei* and Hamed Mirzaei*


DOI: 10.2174/0929867326666191212102407


Review Article

Marine natural products with high anticancer activities

, 2020; 27(8): 1243-1307.

Dario Matulja, Karlo Wittine, Nela Malatesti, Sylvain Laclef, Maris Turks, Maria Kolympadi Markovic, Gabriela Ambrožić and Dean Marković*


DOI: 10.2174/0929867327666200113154115



Most Accessed Articles

Drug Repurposing: Promises of Edaravone Target Drug in Traumatic Brain Injury

, 2021; 28(12): 2369-2391.

Zaynab Shakkour, Hawraa Issa, Helene Ismail, Ohanes Ashekyan, Karl John Habashy, Leila Nasrallah, Hussam Jourdi, Eva Hamade, Stefania Mondello, Mirna Sabra*, Kazem Zibara* and Firas Kobeissy*


DOI: 10.2174/0929867327666200812221022


Machine Learning-Based Scoring Functions, Development and Applications with SAnDReS

, 2021; 28(9): 1746-1756.

Gabriela Bitencourt-Ferreira, Camila Rizzotto and Walter Filgueira de Azevedo Junior*


DOI: 10.2174/0929867327666200515101820





Dual-target Inhibitors Based on BRD4: Novel Therapeutic Approaches for Cancer

, 2021; 28(9): 1775-1795.

Sitao Zhang, Yanzhao Chen, Chengsen Tian, Yujing He, Zeru Tian, Yichao Wan and Tingting Liu*


DOI: 10.2174/0929867327666200610174453


Recent Advances in c-Jun N-Terminal Kinase (JNK) Inhibitors

, 2021; 28(3): 607-627.

Gang Li, Wenqing Qi, Xiaoxun Li, Jinwu Zhao, Meihua Luo and Jianjun Chen*


DOI: 10.2174/0929867327666200210144114


Insights into RNA-dependent RNA Polymerase Inhibitors as Antiinfluenza Virus Agents

, 2021; 28(6): 1068-1090.

Ilaria Giacchello, Francesca Musumeci*, Ilaria D’Agostino, Chiara Greco, Giancarlo Grossi and Silvia Schenone


DOI: 10.2174/0929867327666200114115632



Monoclonal Antibodies: A Prospective and Retrospective View

, 2021; 28(3): 435-471.

Jwala Sivaccumar*, Annamaria Sandomenico*, Luigi Vitagliano and Menotti Ruvo*


DOI: 10.2174/0929867327666200219142231


Advances in L-Type Calcium Channel Structures, Functions and Molecular Modeling

, 2021; 28(3): 514-524.

Lei Xu*, Lilei Sun, Liangxu Xie, Shanzhi Mou, Dawei Zhang, Jingyu Zhu and Peng Xu*


DOI: 10.2174/0929867327666200714154059


Targeting COVID-19 in Parkinson’s Patients: Drugs Repurposed

, 2021; 28(12): 2392-2408.

Firoz Anwar*, Salma Naqvi, Fahad A. Al-Abbasi, Nauroz Neelofar, Vikas Kumar, Ankit Sahoo and Mohammad Amjad Kamal*


DOI: 10.2174/0929867327666200903115138



Antidepressants and Antipsychotic Agents as Repurposable Oncological Drug Candidates

, 2021; 28(11): 2137-2174.

Michał Antoszczak, Anna Markowska, Janina Markowska and Adam Huczyński*


DOI: 10.2174/0929867327666200907141452





Editor-in-Chief

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
Cambridge
(UK)
Biography
View Full Editorial Board

Nobel Laureates on Editorial Board

graphic
Prof. John Gurdon
(UK)

graphic
Prof. Jean-Marie Lehn
(France)

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Prof. Ferid Murad
(USA)

COPE Compliant

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Journal History

Current Medicinal Chemistry was introduced in 1994 with the assistance of Dr. Atta-ur-Rahman, who is the current Editor-in-Chief serving since 1994.

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