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Current Molecular Pharmacology

Volume 14, 6 Issues, 2021
ISSN: 1874-4702 (Online)
ISSN: 1874-4672 (Print)
This journal supports open access

Aims & Scope

Current Molecular Pharmacology aims to publish the latest developments in cellular and molecular pharmacology with a major emphasis on the mechanism of action of novel drugs under development, innovative pharmacological technologies, cell signaling, transduction pathway analysis, genomics, proteomics, and metabonomics applications to drug action. An additional focus will be the way in which normal biological function is illuminated by knowledge of the action of drugs at the cellular and molecular level. The journal publishes full-length/mini reviews, original research articles and thematic issues on molecular pharmacology.

Current Molecular Pharmacology is an essential journal for every scientist who is involved in drug design and discovery, target identification, target validation, preclinical and clinical development of drugs therapeutically useful in human disease.

Current Molecular Pharmacology

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Volume 14

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Number 2







Review Article (Mini-Review)





Review Article (Mini-Review)









Current Molecular Pharmacology, Volume 14 (2021) - Number 3


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Anticancer Effects of Tacrolimus on Induced Hepatocellular Carcinoma in Mice


Shireen Sami Mahmoud, Samia Hussein*, Hayam Rashed, Eman M. A. Abdelghany and Alaa I. Ali


DOI: 10.2174/1874467214666210531164546
View Abstract View on PubMed




Curcumin Efficacy in a Serum/glucose Deprivation-induced Neuronal PC12 Injury Model


Tahereh Farkhondeh, Milad Ashrafizadeh, Mohsen Azimi-Nezhad, Fariborz Samini, Michael Aschner and Saeed Samarghandian*


DOI: 10.2174/1874467214666210203211312
View Abstract View on PubMed


Assessment of Antioxidant Effect of Beta-Glucan on the Whole Blood Oxidative DNA Damage with the Comet Assay in Colorectal Cancer


Necla Benlier, Nilay Uçar, Eda Öğüt, Havva Yeşil Çinkir, Mustafa Yildirim, Pınar Günel Karadeniz, Esra Küpeli Akkol*, Haroon Khan and Eyüp Ilker Saygili*


DOI: 10.2174/1874467214666210219145445
View Abstract View on PubMed



Anticancer Effects of Ginsenoside Rh2: A Systematic Review


Xin-Ling He, Xiao-Huang Xu, Jia-Jie Shi, Mingqing Huang, Yitao Wang, Xiuping Chen and Jin-Jian Lu*


DOI: 10.2174/1874467214666210309115105
View Abstract View on PubMed


Harnessing the Natural Pool of Polyketide and Non-ribosomal Peptide Family: A Route Map towards Novel Drug Development


Aiswarya Girija, Mallika Vijayanathan*, Sweda Sreekumar , Jasim Basheer , Tara G Menon, Radhakrishnan Edayileveetil Krishnankutty and Eppurathu Vasudevan Soniya*


DOI: 10.2174/1874467214666210319145816
View Abstract View on PubMed




Abstracts Ahead of Print




Exercise and Nutraceuticals: Eminent approach for Diabetic Neuropathy


Mayur Bhimrao Kale, Komal Bajaj, Mohit Umare, Nitu L. Wankhede, Brijesh Gulabrao Taksande, Milind Janrao Umekar and Aman Upaganlawar*


DOI: 10.2174/1874467214666210629123010
View Abstract



Advances in research on microRNAs related to the invasion and metastasis of nasopharyngeal carcinoma


ShanShan Zhang, BaiQi Wang, LuLu Zheng, ZhuQiong Fu, YiTing Fu, WeiGuo Huang and AiLan Cheng*


DOI: 10.2174/1874467214666210614150720
View Abstract





Pretreatment with Gallic Acid Mitigates Cyclophosphamide Induced Inflammation and Oxidative Stress in Mice


Saeed Baharmi, Heibatullah Kalantari, Mojtaba Kalantar, Mehdi Goudarzi, Esrafil Mansouri and Hadi Kalantar*


DOI: 10.2174/1874467214666210531162741
View Abstract


Published Contents

Editor's Choice

Recent Advances in Herbal Nanomedicines for Cancer Treatment

, 2021; 14(3): 292 - 305

Deepak Pradhan, Prativa Biswasroy, Amita Sahu, Dipak K. Sahu, Goutam Ghosh and Goutam Rath*


DOI: 10.2174/1874467213666200525010624



Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression

, 2021; 14(3): 321 - 332

Saurabh Satija*, Harpreet Kaur, Murtaza M. Tambuwala, Prabal Sharma, Manish Vyas, Navneet Khurana, Neha Sharma, Hamid A. Bakshi, Nitin B. Charbe, Flavia C. Zacconi, Alaa A. Aljabali, Srinivas Nammi, Harish Dureja, Thakur G. Singh, Gaurav Gupta, Daljeet S. Dhanjal, Kamal Dua, Dinesh K. Chellappan* and Meenu Mehta*


DOI: 10.2174/1874467214666210120154929



TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy

, 2021; 14(2): 123 - 131

Kazuhiro Nishiyama, Tomohiro Tanaka, Akiyuki Nishimura and Motohiro Nishida*


DOI: 10.2174/1874467213666200407090121



Molecular Mechanisms Involved in the Progression and Protection of Osteoarthritis

, 2021; 14(2): 165 - 169

Yoshifumi Takahata*, Tomohiko Murakami, Kenji Hata and Riko Nishimura


DOI: 10.2174/1874467213666200417122933




Hepatic Stellate Cell: A Potential Target for Hepatocellular Carcinoma

, 2020; 13(4): 261 - 272

Mengna Wu, Huajie Miao, Rong Fu, Jie Zhang* and Wenjie Zheng *


DOI: 10.2174/1874467213666200224102820




Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents

, 2020; 13(3): 216 - 223

Tatiana V. Vyunova*, Lioudmila A. Andreeva, Konstantin V. Shevchenko, Vladimir V. Grigoriev, Vladimir A. Palyulin, Mstislav I. Lavrov, Ekaterina V. Bondarenko, Elena E. Kalashnikova and Nikolay F. Myasoedov


DOI: 10.2174/1874467213666200303140834



Discovering Therapeutic Protein Targets for Bladder Cancer Using Proteomic Data Analysis

, 2020; 13(2): 150 - 172

Samira Bahrami, Bahram Kazemi*, Hakimeh Zali, Peter C. Black, Abbas Basiri, Mojgan Bandehpour, Mehdi Hedayati and Amirhossein Sahebkar


DOI: 10.2174/1874467212666191016124935




Open Access Articles

Lactoferrin Suppresses Decreased Locomotor Activities by Improving Dopamine and Serotonin Release in the Amygdala of Ovariectomized Rats

, 2021; 14(2): 245 - 252

Nobuo Izumo*, Ishibashi Yukiko, Nobuharu Kagaya, Megumi Furukawa, Rina Iwasaki, Akihide Sumino, Kohsuke Hayamizu, Makoto Nakano, Tatsuo Hoshino, Haruna Kurono, Yasuo Watanabe and Takayuki Manabe*





Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway

, 2021; 14(1): 101 - 111

Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao*, Li-Chun Zhao* and Shilin Yang




Ticagrelor Ameliorates Bleomycin-induced Pulmonary Fibrosis in Rats by the Inhibition of TGF-β1/Smad3 and PI3K/AKT/mTOR Pathways

, 2021; 14: 1 - 12 (E-Pub Ahead of Print)

Hanaa Wanas*, Zeinab El Shereef, Laila Rashed and Basma Emad Aboulhoda




New Insights in Cannabinoid Receptor Structure and Signaling

, 2019; 12(3): 239 - 248

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*





Targeting Chromatin Remodeling for Cancer Therapy

, 2019; 12(3): 215 - 229

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*




Mitochondria-Targeted Drugs

, 2019; 12(3): 202 - 214

Roman A. Zinovkin* and Andrey A. Zamyatnin*




A Contemporary Overview of PPARα/γ Dual Agonists for the Management of Diabetic Dyslipidemia

, 2019; 12(3): 195 - 201

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar




Pharmacokinetic and Pharmacodynamic Aspects of Peyote and Mescaline: Clinical and Forensic Repercussions

, 2019; 12(3): 184 - 194

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva




Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis

, 2019; 12(1): 27 - 49

Shahinda S.R. Alsayed, Chau C. Beh, Neil R. Foster, Alan D. Payne, Yu Yu and Hendra Gunosewoyo*




Anticancer Mechanism of Lobaplatin as Monotherapy and in Combination with Paclitaxel in Human Gastric Cancer

, 2018; 11(4): 316 - 325

Suhang Hua, Xiangyu Kong, Binbin Chen, Wenxin Zhuang, Qian Sun, Wei Yang, Wenzhi Liu* and Yongxing Zhang*





Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures

, 2017; 10(4): 334 - 344

Andrew S. Dore, Andrea Bortolato, Kaspar Hollenstein, Robert K.Y. Cheng, Randy J. Read and Fiona H. Marshall*






Most Cited Articles

Review Article

New insights in cannabinoid receptor structure and signaling

, 2019; 12(3): 239-248.

Lingyan Ye, Zheng Cao, Weiwei Wang and Naiming Zhou*


DOI: 10.2174/1874467212666190215112036


Review Article

Mitochondria-targeted drugs

, 2019; 12(3): 202-214.

Roman A. Zinovkin* and Andrey A. Zamyatnin*


DOI: 10.2174/1874467212666181127151059


Review Article

NADPH oxidase as a target for modulation of radiation response; implications to carcinogenesis and radiotherapy

, 2019; 12(1): 50-60.

Keywan Mortezaee, Nasser Hashemi Goradel, Peyman Amini, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Masoud Najafi* and Bagher Farhood*


DOI: 10.2174/1874467211666181010154709




Review Article

Mechanisms for radioprotection by melatonin; can it be used as a radiation countermeasure?

, 2019; 12(1): 2-11.

Peyman Amini, Hanifeh Mirtavoos-Mahyari, Elahe Motevaseli, Dheyauldeen Shabeeb, Ahmed Eleojo Musa, Mohsen Cheki, Bagher Farhood, Rasoul Yahyapour, Alireza Shirazi, Nouraddin Abdi Goushbolagh and Masoud Najafi*


DOI: 10.2174/1874467211666180802164449


Review Article

Pharmacokinetic and pharmacodynamic aspects of peyote and mescaline: Clinical and forensic repercussions

, 2019; 12(3): 184-194.

Ricardo Jorge Dinis-Oliveira*, Carolina Lança Pereira and Diana Dias da Silva


DOI: 10.2174/1874467211666181010154139


Research Article

In-vitro pre-treatment of cancer cells with TGF-β1: A novel approach of tail vein lung cancer metastasis mouse model for anti-metastatic studies

, 2019; 12(4): 249-260.

Ghulam Jilany Khan*, Li Sun, Muhammad Abbas, Muhammad Naveed, Talha Jamshaid, Mirza Muhammad Faran Ashraf Baig and Shengtao Yuan*


DOI: 10.2174/1874467212666190306165703


Research Article

Effects of myo-inositol alone and in combination with seleno-l-methionine on cadmium-induced testicular damage in mice

, 2019; 12(4): 311-323.

Salvatore Benvenga, Antonio Micali*, Giovanni Pallio, Roberto Vita, Consuelo Malta, Domenico Puzzolo, Natasha Irrera, Francesco Squadrito, Domenica Altavilla and Letteria Minutoli


DOI: 10.2174/1874467212666190620143303


Review Article

Targeting chromatin remodeling for cancer therapy

, 2019; 12(3): 215-229.

Jasmine Kaur, Abdelkader Daoud and Scott T. Eblen*


DOI: 10.2174/1874467212666190215112915



Review Article

Kinase targets for mycolic acid biosynthesis in mycobacterium tuberculosis

, 2019; 12(1): 27-49.

Shahinda S.R. Alsayed, Chau C. Beh, Neil R. Foster, Alan D. Payne, Yu Yu and Hendra Gunosewoyo*


DOI: 10.2174/1874467211666181025141114


Research Article

Mir-4319 suppresses the growth of esophageal squamous cell carcinoma via targeting NLRC5

, 2020; 13(2): 144-149.

Xiao Hu, Min Wang, Lei Cao, Li Cong, Yujie Gao, Jianwei Lu, Jifeng Feng, Bo Shen and Delin Liu*


DOI: 10.2174/1874467212666191119094636


Research Article

Synergistic effect of epigenetic inhibitors decitabine and suberoylanilide hydroxamic acid on colorectal cancer in vitro

, 2019; 12(4): 281-300.

Sonia Abou Najem, Ghada Khawaja, Mohammad Hassan Hodroj and Sandra Rizk*


DOI: 10.2174/1874467212666190313154531


Review Article

A contemporary overview of PPARα/γ dual agonists for the management of diabetic dyslipidemia

, 2019; 12(3): 195-201.

Pitchai Balakumar*, Nanjaian Mahadevan and Ramanathan Sambathkumar


DOI: 10.2174/1874467212666190111165015



Most Accessed Articles



Recent Advances in Herbal Nanomedicines for Cancer Treatment

, 2021; 14(3): 292-305.

Deepak Pradhan, Prativa Biswasroy, Amita Sahu, Dipak K. Sahu, Goutam Ghosh and Goutam Rath*


DOI: 10.2174/1874467213666200525010624


Protective Potential of Ginkgo biloba Against an ADHD-like Condition

, 2021; 14(2): 200-209.

Garima Sharma, Naveen Sharma, Bao Trong Nguyen, Ji Hoon Jeong, Seung-Yeol Nah, Yukio Yoneda, Eun-Joo Shin and Hyoung-Chun Kim*


DOI: 10.2174/1874467213666200424152454


Hypoxia-Inducible Factor (HIF): Fuel for Cancer Progression

, 2021; 14(3): 321-332.

Saurabh Satija*, Harpreet Kaur, Murtaza M. Tambuwala, Prabal Sharma, Manish Vyas, Navneet Khurana, Neha Sharma, Hamid A. Bakshi, Nitin B. Charbe, Flavia C. Zacconi, Alaa A. Aljabali, Srinivas Nammi, Harish Dureja, Thakur G. Singh, Gaurav Gupta, Daljeet S. Dhanjal, Kamal Dua, Dinesh K. Chellappan* and Meenu Mehta*


DOI: 10.2174/1874467214666210120154929






Actions of Alcohol in Brain: Genetics, Metabolomics, GABA Receptors, Proteomics and Glutamate Transporter GLAST/EAAT1

, 2021; 14(2): 138-149.

Mohammed Abul Kashem, Omar Šerý, David V. Pow, Benjamin D. Rowlands, Caroline D. Rae and Vladimir J. Balcar*


DOI: 10.2174/1874467213666200424155244



TRPC3-Based Protein Signaling Complex as a Therapeutic Target of Myocardial Atrophy

, 2021; 14(2): 123-131.

Kazuhiro Nishiyama, Tomohiro Tanaka, Akiyuki Nishimura and Motohiro Nishida*


DOI: 10.2174/1874467213666200407090121




Differential Modulation of Autophagy Contributes to the Protective Effects of Resveratrol and Co-Enzyme Q10 in Photoaged Mice

, 2021; 14(3): 458-468.

Dalia K. Mostafa*, Shaimaa I. Omar, Amany A. Abdellatif, Osama A. Sorour, Omnia A. Nayel and Marwa R. Abod Al Obaidi


DOI: 10.2174/1874467213666200730114547




Editor-in-Chief

graphic
Michael Kahn
(16435 citations)
Beckman Research Institute
City of Hope
Duarte, CA 91010-3000
(USA)
View Full Editorial Board

COPE Compliant

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Journal History

Current Molecular Pharmacology Journal was launched in 2008. Prof. Michael Kahn serves as the Editor-in-Chief of the journal.

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