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Current Topics in Medicinal Chemistry

Volume 21, 32 Issues, 2021
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access


Current Topics in Medicinal Chemistry, Volume 14 - Number 10

Recent Advances on the Enantioselective Synthesis of C-Nucleosides Inhibitors of Inosine Monophosphate Dehydrogenase (IMPDH)

, 14(10): 1212 - 1224

Pedro Merino, Mattia Ghirardello, Tomas Tejero, Ignacio Delso and Rosa Matute

DOI: 10.2174/1568026614666140423095331

Conformational Preferences of Chiral Acyclic Homooligomeric β2,2-Peptides

, 14(10): 1225 - 1234

Fernando Rodriguez, Francisco Corzana, Alberto Avenoza, Jesus Hector Busto, Jesus Manuel Peregrina and Maria del Mar Zurbano

DOI: 10.2174/1568026614666140423101226

Enantioselective Synthesis in Carbohydrate-Based Drug Discovery: Imino Sugars, Alkaloids and Macrolide Antibiotics

, 14(10): 1235 - 1243

Nuno M. Xavier and Amélia P. Rauter

DOI: 10.2174/1568026614666140423103848

Chiral Thiazoline and Thiazole Building Blocks for the Synthesis of Peptide- Derived Natural Products

, 14(10): 1244 - 1256

Xavier Just-Baringo, Fernando Albericio and Mercedes Alvarez

DOI: 10.2174/1568026614666140423105730

Enantiopure 1,2,3-Triazolyl-β-amino Acids via Click Cycloaddition Reaction on Racemic Alkynyl Precursors Followed by Separation of Stereoisomers

, 14(10): 1257 - 1270

Margarita Escudero-Casao, Alberto Vega-Penaloza and Eusebio Juaristi

DOI: 10.2174/1568026614666140423110420

Asymmetric 1,3-Dipolar Cycloadditons of Stabilized Azomethine Ylides with Nitroalkenes

, 14(10): 1271 - 1282

Carmen Nejera and Jose M. Sansano

DOI: 10.2174/1568026614666140423112145

Enantioselective Synthesis of PPAR (Peroxisome Proliferator-Activated Receptors) Agonists and Antagonists

, 14(10): 1283 - 1293

Pilar Goya, Ruth Perez-Fernandez, Rosario Gonzalez-Muniz and Jose Elguero

DOI: 10.2174/1568026614666140423112822

Recent Syntheses and Biological Activity of Lentiginosine and its Analogues

, 14(10): 1294 - 1307

Franca M. Cordero, Donatella Giomi and Alberto Brandi

DOI: 10.2174/1568026614666140423113226

Stereoselective Synthesis of Polysubstituted Piperazines and Oxopiperazines. Useful Building Blocks in Medicinal Chemistry

, 14(10): 1308 - 1316

Alessandro Mordini, Gianna Reginato, Massimo Calamante and Lorenzo Zani

DOI: 10.2174/1568026614666140423114013

Base Free Catalyzed Enantioselective Michael Reaction of bis(phenylsulfonyl)methane to α,β -Unsaturated Aldehydes under Iminium Activation

, 14(10): 1317 - 1322

Beatriz Alonso, Uxue Uria, Luisa Carrillo, Jose L. Vicario and Efraim Reyes

DOI: 10.2174/1568026614666140423114516


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
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Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who served as the editor-in-chief from 2001 to 2020. Currently, Dr. Jia Zhou is the Editor-in-Chief of the journal.

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