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Current Topics in Medicinal Chemistry

Volume 21, 32 Issues, 2021
ISSN: 1873-4294 (Online)
ISSN: 1568-0266 (Print)
This journal supports open access


Current Topics in Medicinal Chemistry, Volume 16 - Number 4

Metalloprotein Inhibitors for the Treatment of Human Diseases

, 16(4): 384 - 396

Yang Yang, Xue-Qin Hu, Qing-Shan Li, Xing-Xing Zhang, Ban-Feng Ruan, Jun Xu and Chenzhong Liao

DOI: 10.2174/1568026615666150813145218

Advances in Bacterial Methionine Aminopeptidase Inhibition

, 16(4): 397 - 414

Travis R. Helgren, Phumvadee Wangtrakuldee, Bart L. Staker and Timothy J. Hagen

DOI: 10.2174/1568026615666150813145410

Selective Histone Deacetylase Inhibitors with Anticancer Activity

, 16(4): 415 - 426

Nan Ma, Ying Luo, Ying Wang, Chenzhong Liao, Wen-Cai Ye and Sheng Jiang

DOI: 10.2174/1568026615666150813145629

6,7-Dihydroxyisoindolin-1-one and 7,8-Dihydroxy-3,4-Dihydroisoquinolin- 1(2H)-one Based HIV-1 Integrase Inhibitors

, 16(4): 435 - 440

Xue Zhi Zhao, Mathieu Métifiot, Steven J. Smith, Kasthuraiah Maddali, Christophe Marchand, Stephen H. Hughes, Yves Pommier, Terrence R. Burke and Jr.

DOI: 10.2174/1568026615666150813150058

Novel HIV-1 Integrase Inhibitor Development by Virtual Screening Based on QSAR Models

, 16(4): 441 - 448

Laura Guasch, Alexey V. Zakharov, Olga A. Tarasova, Vladimir V. Poroikov, Chenzhong Liao and Marc C. Nicklaus

DOI: 10.2174/1568026615666150813150433

Non-Zinc-Binding Inhibitors of MMP-13: GRID-Based Approaches to Rationalize the Binding Process

, 16(4): 449 - 459

Antonella Di Pizio, Mariangela Agamennone and Paolo Tortorella

DOI: 10.2174/1568026615666150813150631

In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis

, 16(4): 460 - 466

Hong Zhang, Jing Zhai, Liping Zhang, Cuiyun Li, Yining Zhao, Yunyun Chen, Qing Li and Xiao Peng Hu

DOI: 10.2174/1568026615666150813150944


Jia Zhou
Chemical Biology Program
Department of Pharmacology and Toxicology
University of Texas Medical Branch
Galveston, TX
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Journal History

Current Topics in Medicinal Chemistry was introduced in 2001 with the assistance of Dr. Allen B. Reitz, who served as the editor-in-chief from 2001 to 2020. Currently, Dr. Jia Zhou is the Editor-in-Chief of the journal.

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