Drug Metabolism Letters
Continued as: Drug Metabolism and Bioanalysis Letters
Volume 15, 3 Issues, 2022
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access
Contents
Drug Metabolism Letters , Volume 10 - Number 2
Editorial
Commentary: A Myriad Aberrations on Information of Ontogeny of Drug Metabolizing Enzymes in the Pediatric Population: An Obstacle for Personalizing Drug Therapy in the Pediatric Population
, 10(2): 72 - 74Chakradhara Rao S. Uppugunduri and Marc Ansari
DOI: 10.2174/1872312810666160224143443
The Effects of Statin Therapy on the Human Airway
, 10(2): 75 - 82Lorraine Thong, John MacSharry and Desmond M. Murphy
DOI: 10.2174/1872312810666160303112012
Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability
, 10(2): 83 - 90Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam
DOI: 10.2174/1872312810666160223121836
Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat
, 10(2): 91 - 100Kirsten Messick, Matthew Wright, S. Cyrus Khojasteh, Lesley J. Murray, Joachim Rudolf, James J. Crawford, Wendy Lee, Shannon Liu, Nicole Valle, Peter W. Fan, Matthew Durk, Robert T. Cass, Teresa Mulder, Ning Liu, Hank La, M. Allan Jaochico and Jacob Z. Chen
DOI: 10.2174/1872312810666160411144358
In Vitro Study of UGT Metabolism and Permeability of Orientin and Isoorientin, Two Active flavonoid C-glycosides
, 10(2): 101 - 110Jian Shi, Lijun Zhu, Ye Li, Haihui Zheng, Jia Yu, Linlin Lu and Zhongqiu Liu
DOI: 10.2174/1872312810666160219121217
Biotransformation of Cobicistat: Metabolic Pathways and Enzymes
, 10(2): 111 - 123Pengcheng Wang, Amina I. Shehu, Ke Liu, Jie Lu and Xiaochao Ma
DOI: 10.2174/1872312810666160303112212
In Vitro CYP2D Inhibitory Effect and Influence on Pharmacokinetics and Pharmacodynamic Parameters of Metoprolol Succinate by Terminalia arjuna in Rats
, 10(2): 124 - 135Alice Varghese, Jay Savai, Shruti Mistry, Preeti Khandare, Kalyani Barve, Nancy Pandita and Ram Gaud
DOI: 10.2174/1872312810666160219121415
Elucidating the Mechanism of Tofacitinib Oxidative Decyanation
, 10(2): 136 - 143Hoa Le, Peter W. Fan, Susan Wong, Shuguang Ma, James P. Driscoll, Cornelis E.C.A. Hop and S. Cyrus Khojasteh
DOI: 10.2174/1872312810666160427104954
Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation
, 10(2): 144 - 150Julius L. Apuy, Cathie Xiang, Sarah Franc, Sayee G. Hegde, Robert Hubbard, Jingjing Zhao and Mehran F. Moghaddam
DOI: 10.2174/1872312810666160511150558
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