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Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 21, 12 Issues, 2021
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

,

Volume 21

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Number 9





Review Article

Covid-19 in Man: A Very Dangerous Affair

, 21(9): 1544 - 1554

Giuseppe Lisco, Vito A. Giagulli, Giovanni De Pergola, Anna De Tullio, Edoardo Guastamacchia and Vincenzo Triggiani*


DOI: 10.2174/1871530321666210101123801




Research Article

Anti-Inflammatory Effect of KW-2449 on Autoimmune Encephalomyelitis: An Experimental Study on Mice

, 21(9): 1590 - 1597

Hasan N. Ahmadabad, Allireza Abbaspour, Yaser Panahi, Saeed Tahmasebi, Nikoo Hossein-Khannazer, Sanaz Afraei*, Hosein Miladi, Mahdi Goudarzvand, Ali N. Kamali, Yasser Bagheri, Reza Yazdani, Maria M. Di Fiore and Gholamreza Azizi*


DOI: 10.2174/1871530320666201106095808


Research Article

Prevalence and Clinical Profile of Undiagnosed Diabetes Mellitus: Data from a Tertiary Hospital

, 21(9): 1598 - 1603

Hen H. Phan, Hoang V. Lam, Nhan T. Le, Huy N. Le, Diem T. Tran, An V. Tran, Thao P. Mai and Minh D. Do*


DOI: 10.2174/1871530320666201014151408




Research Article

Relationship Among Adherence to the Mediterranean Diet and Anthropometric and Metabolic Parameters in Subjects with Obesity

, 21(9): 1613 - 1619

Luisa Lampignano, Roberta Zupo, Rossella Donghia, Vito Guerra, Fabio Castellana, Isanna Murro, Carmen Di Noia, Rodolfo Sardone, Gianluigi Giannelli, Vincenzo Triggiani and Giovanni De Pergola*


DOI: 10.2174/1871530320999201111161220




Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 21 (2021) - Number 10


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Circulating Biomarkers Related to Osteocyte and Calcium Homeostasis Between Postmenopausal Women with and without Osteoporosis


Chin Yi Chan, Shaanthana Subramaniam, Norazlina Mohamed, Norliza Muhammad, Fitri Fareez Ramli, Soelaiman Ima-Nirwana and Kok-Yong Chin*


DOI: 10.2174/1871530321666210809154456
View Abstract View on PubMed






Assessment of Burnout Levels Before and During COVID-19 Pandemic: A Web-Based Survey by the (Italian) Association of Medical Endocrinologists (AME)


Yura Loscalzo*, Simonetta Marucci, Piernicola Garofalo, Roberto Attanasio, Giuseppe Lisco*, Vincenzo De Geronimo, Edoardo Guastamacchia, Marco Giannini and Vincenzo Triggiani


DOI: 10.2174/1871530321666210720123336
View Abstract View on PubMed



Genetic Screening of Patients with Thyrotoxic Hypokalemic Periodic Paralysis: An Experience from a Tertiary Care Hospital in the Northeast of Brazil


Cossi Y. Gbefon, Carla P. S. Sobral, Adriana Caldas, Viviane C. C. Rocha, Rossana S. S. Azulay, Gilvan C. Nascimento, Sabrina S. P. Damianse, Silvia A. S. Gaspar, Manuel S. Faria and Marcelo Magalhães*


DOI: 10.2174/1871530321666210719114937
View Abstract



An Alternative “Trojan Horse” Hypothesis for COVID-19: Immune Deficiency of IL-10 and SARS-CoV-2 Biology


Mario Giosuè Balzanelli, Pietro Distratis, Sergey K Aityan, Felice Amatulli, Orazio Catucci, Angelo Cefalo, Antonia De Michele, Gianna Dipalma, Francesco Inchingolo, Rita Lazzaro, Cao Diem Kiew Nguyen, Davide Palazzo, Marilina Tampoia, Pham Hung Van, Luigi Santacroce* and Ciro Gargiulo Isacco


DOI: 10.2174/1871530321666210127141945
View Abstract View on PubMed


Abstracts Ahead of Print

A Simple Scoring Model Predicting the Outcome of COVID-19 Patients: Tanta COVID score


Mohammed Elhendawy, Ferial El-Kalla, Sherief Abd-Elsalam*, Dalia ElSharawy, Shaimaa S Soliman , Dina Abdelhai , Maha M Hagras, Mai Khalaf, Eslam Saber Esmail and Abdelrahman Kobtan


DOI: 10.2174/1871530321666211126104952
View Abstract


Bilirubin and Epigenetic Modifications in Metabolic and Immunometabolic Disorders


Mostafa Moradi Sarabi, Esmaeel Babaeenezhad, Maral Amini, Mozhgan Kaviani and Fakhraddin Naghibalhossaini*


DOI: 10.2174/1871530321666211125102924
View Abstract



Effects of Bacterial Metabolites on the Immune System: Enemies and Friends


Zaaima Al-Jabri, Iman Al-Reesi, Nawal Al-Shizawi, Mohammed S. Al-Balushi, Ali A. Al-Jabri and Elias A. Said*


DOI: 10.2174/1871530321666211119150231
View Abstract



Role of Polyphenol in Regulating Oxidative Stress, Inflammation, Fibrosis, and Apoptosis in Diabetic Nephropathy


Syaifuzah Sapian, Siti Balkis Budin*, Izatus Shima Taib, Vanitha Mariappan, Satirah Zainalabidin and Kok Yong Chin


DOI: 10.2174/1871530321666211119144309
View Abstract




Eating Disorders and Type 1 Diabetes: a perspective


Simonetta Marucci*, Giulia De Iaco, Giuseppe Lisco, Francesco Mariano, Vito Angelo Giagulli, Edoardo Guastamacchia, Giovanni De Pergola and Vincenzo Triggiani


DOI: 10.2174/1871530321666211109152353
View Abstract



Published Contents

Editor's Choice


Can Cytokines be used as an Activation Marker in Rheumatoid Arthritis?

, 2021; 21(8): 1459 - 1465

Fatih Öner Kaya, Yeşim Ceylan, Belkız Öngen İpek, Zeynep Güneş Özünal, Gülbüz Sezgin and Selim Nalbant*


DOI: 10.2174/1871530320666201019115030



Benfotiamine Reduces Dendritic Cell Inflammatory Potency

, 2021; 21(7): 1344 - 1351

Neda Djedovic, Iva Božić, Đorđe Miljković* and Irena Lavrnja


DOI: 10.2174/1871530320999200905114135



Acute Versus Chronic Administration of Calcineurin-Inhibitors Differentially Affect T-Cell Function

, 2021; 21(6): 1083 - 1089

Julia Kirchhof, Benjamin Wilde*, Justine Schmidt, Nils Mülling, Liubov Petrakova, Alexandra Brinkhoff, Manfred Schedlowski and Oliver Witzke


DOI: 10.2174/1871530320999200831161710



The Effects of Pemafibrate in Japanese Patients with Type 2 Diabetes Receiving HMG-CoA Reductase Inhibitors

, 2021; 21(5): 919 - 924

Masataka Kusunoki*, Takahiko Sakazaki, Kazuhiko Tsutsumi, Tetsuro Miyata and Yoshiharu Oshida


DOI: 10.2174/1871530320999200818135553



Downregulation of miR-140 is Correlated with Poor Prognosis and Progression of Thyroid Cancer

, 2021; 21(4): 749 - 755

Qianqian Yu, Wenhai Sun, Hui Hua, Yulian Chi, Xiaomin Liu, Anbing Dong, Yinghe Sun, Jianhua Zhang and Ge Guan*


DOI: 10.2174/1871530320666200724180742



T Cell Proliferative Responses and IgG Antibodies to β2GPI in Patients with Diabetes and Atherosclerosis

, 2021; 21(3): 495 - 503

Mohammad R. Monjezi, Hamed Fouladseresht, Shirin Farjadian, Behrouz Gharesi-Fard, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530320666200505115850



Positive Correlation between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men

, 2021; 21(2): 338 - 344

Reza Afrisham, Maliheh Paknejad, Davod Ilbeigi, Sahar Sadegh-Nejadi, Sattar Gorgani-Firuzjaee* and Mahmoud Vahidi*


DOI: 10.2174/1871530320666200601164253




Time-Dependent Effects in Chronic Urticaria: A Time-Series Perspective of Omalizumab Treatment

, 2020; 20(10): 1726 - 1739

Anna Tagka*, George I. Lambrou, Michael Makris, Evangelia Nakou, Electra Nicolaidou , Argyro Chatziioannou and Alexandra Katsarou


DOI: 10.2174/1871530320666200313151720



Open Access Articles

Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome

, 2021; 21(10): 1920 - 1928

Raida Khalil, Wajdy J. Al-Awaida, Hamzeh J. Al-Ameer*, Yazun Jarrar, Amer Imraish, Omar Al bawareed, Rand Qawadri, Farah Al Madhoon and Loiy Obeidat




The Skeletal Effects of Gonadotropin-Releasing Hormone Antagonists: A Concise Review

, 2021; 21(10): 1713 - 1720

Nur-Vaizura Mohamad, Soelaiman Ima-Nirwana and Kok-Yong Chin*




How Much Vitamin D is Too Much? A Case Report and Review of the Literature

, 2021; 21(9): 1653 - 1659

Sara De Vincentis*, Antonino Russo, Marta Milazzo, Amedeo Lonardo, Maria C. De Santis, Vincenzo Rochira, Manuela Simoni and Bruno Madeo




False Positive of 68Ga-DOTATATE PET-CT in a Paraganglioma

, 2021; 21(7): 1352 - 1355

Benedetta Zampetti, Roberto Attanasio*, Marco Boniardi and Renato Cozzi




Exploration of SQC Formula Effect on Type 2 Diabetes Mellitus by Whole Transcriptome Profile in Rats

, 2021; 21(7): 1261 - 1269

Xiaoxu Fu, Xiujuan Zhou, Ya Liu, Yuanhong Lei, Hongyan Xie, Yulin Leng, Hong Gao* and Chunguang Xie*




Hidden Hunger of Vitamin E among Healthy College Students: A Cross- Sectional Study

, 2021; 21(6): 1025 - 1030

Zhongqi Wan, Li Wang, Yinyang Xu, Yuanyuan Wang, Tianyou Zhang, Xinlan Mao, Qiao Li, Yangzhi Zhu, Ming Zhou* and Zhong Li*




Evaluation of Gamma Amino Butyric Acid (GABA) and Glibenclamide Combination Therapy in Streptozotocin Induced Diabetes

, 2021; 21: 1 - 12 (E-Pub Ahead of Print)

Yunfeng Zhu, Sushma Devi*, Manish Kumar*, Randhir Singh Dahiya and Tarkeshwer





Post-Exercise Ketosis, Salivary Uric Acid and Interleukin-6 after a Simulated Wheelchair Basketball Match

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Anna Raguzzini, Elisabetta Toti, Marco Bernardi, Fabio Castellucci, Valentina Cavedon, Anna Lucia Fedullo, Chiara Milanese, Tommaso Sciarra and Ilaria Peluso*






Appraisal of Anti-Arthritic and Anti-Inflammatory Potential of Folkloric Medicinal Plant Peganum Harmala

, 2021; 21: 1 - 15 (E-Pub Ahead of Print)

Muhammad Furqan Akhtar*, Syed Ahmad Raza, Ammara Saleem*, Irfan Hamid, Mirza Muhammad Faran Ashraf Baig, Ali Sharif, Kashif Sohail, Zeeshan Javaid, Uzma Saleem and Azhar Rasul




Dietary Intakes and Food Habits of Wheelchair Basketball Athletes Compared to Gym Attendees and Individuals who do not Practice Sport Activity

, 2021; 21: 1 - 11 (E-Pub Ahead of Print)

Elisabetta Toti, Valentina Cavedon, Anna Raguzzini, Anna Lucia Fedullo, Chiara Milanese, Elisabetta Bernardi, Sheila Bellito, Marco Bernardi, Tommaso Sciarra and Ilaria Peluso*




Effect of Direct-Acting Antiviral Drugs on Erectile Functions among Hepatitis C Patients: A Prospective Interventional Study

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Mohamed Alhefnawy, Ahmed Mohey, Ahmed Fathi, Ahmed Mansour, Sherief Abd-Elsalam*, Ahmed Eissa, Ayman Hagras, Stefano Puliatti and Khaled Almekaty






Most Cited Articles


Research Article

Probiotics efficacy on oxidative stress values in inflammatory bowel disease: A randomized double-blinded placebo-controlled pilot study

, 2019; 19(3): 373-381.

Andrea Ballini, Luigi Santacroce*, Stefania Cantore, Lucrezia Bottalico, Gianna Dipalma, Skender Topi, Rajiv Saini, Danila De Vito and Francesco Inchingolo


DOI: 10.2174/1871530319666181221150352



Research Article

Hypoglycemic and hypolipemic effects of a new lecithin formulation of bergamot polyphenolic fraction: A double blind, randomized, placebo- controlled study

, 2019; 19(2): 136-143.

Vincenzo Mollace*, Miriam Scicchitano, Sara Paone, Francesca Casale, Carla Calandruccio, Micaela Gliozzi, Vincenzo Musolino, Cristina Carresi, Jessica Maiuolo, Saverio Nucera, Antonella Riva, Pietro Allegrini, Massimo Ronchi, Giovanna Petrangolini and Ezio Bombardelli


DOI: 10.2174/1871530319666181203151513


Review Article

BPA and nutraceuticals, simultaneous effects on endocrine functions

, 2019; 19(5): 594-604.

Stefania D'Angelo, Marika Scafuro and Rosaria Meccariello*


DOI: 10.2174/1871530319666190101120119


Clinical Trial

The neuromodulatory effects of ω-3 fatty acids and nano-curcumin on the COX-2/ iNOS network in migraines: A clinical trial study from gene expression to clinical symptoms

, 2019; 19(6): 874-884.

Mina Abdolahi, Arash Jafarieh, Payam Sarraf, Mohsen Sedighiyan, Abolghasem Yousefi, Abbas Tafakhori, Hamed Abdollahi, Farahnaz Salehinia and Mahmoud Djalali*


DOI: 10.2174/1871530319666190212170140


Research Article

Evaluation of TG-HDL ratio instead of HOMA ratio as insulin resistance marker in overweight and children with obesity

, 2019; 19(5): 676-682.

Eman G. Behiry*, Nazih Mohamed El Nady, Omima M. AbdEl Haie, May Kamel Mattar and Amira Magdy


DOI: 10.2174/1871530319666190121123535


Research Article

Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: Results of a real-world cohort study

, 2020; 20(1): 104-111.

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


DOI: 10.2174/1871530319666190826150344


Research Article

Anti-cancerous effect of rutin against HPV-C33A cervical cancer cells via g0/g1 cell cycle arrest and apoptotic induction

, 2020; 20(3): 409-418.

Fahad Khan, Pratibha Pandey*, Tarun K. Upadhyay, Asif Jafri, Niraj K. Jha, Rashmi Mishra and Vineeta Singh


DOI: 10.2174/1871530319666190806122257


General Research Article

25 hydroxyvitamin D levels are negatively and independently associated with fat mass in a cohort of healthy overweight and obese subjects

, 2019; 19(6): 838-844.

Giovanni De Pergola*, Tommaso Martino, Roberta Zupo, Domenico Caccavo, Claudio Pecorella, Silvia Paradiso, Franco Silvestris and Vincenzo Triggiani


DOI: 10.2174/1871530319666190122094039


General Research Article

Elucidation of the chemopreventive role of stigmasterol against Jab1 in gall bladder carcinoma

, 2019; 19(6): 826-837.

Pratibha Pandey, Preeti Bajpai*, Mohammad H. Siddiqui, Uzma Sayyed, Rohit Tiwari, Rafia Shekh, Kumudesh Mishra and V.K. Kapoor


DOI: 10.2174/1871530319666190206124120


Review Article (Mini-Review)

Quality of life in individuals with diabetic foot syndrome

, 2020; 20(9): 1365-1372.

Emmanuel Navarro-Flores and Omar Cauli*


DOI: 10.2174/1871530320666200128154036



Research Article

Sex-specific association between serum uric acid and elevated alanine aminotransferase in a military cohort: The chief study

, 2019; 19(3): 333-340.

Jia-Wei Lin, Kun-Zhe Tsai, Kai-Wen Chen, Fang-Ying Su, Yi-Hwei Li, Yen-Po Lin, Chih-Lu Han, Felicia Lin, Yu-Kai Lin, Chung-Bao Hsieh and Gen-Min Lin*


DOI: 10.2174/1871530319666181129163802


Research Article

Overexpression of hepassocin in diabetic patients with nonalcoholic fatty liver disease may facilitate increased hepatic lipid accumulation

, 2019; 19(2): 185-188.

Ghada Abdelmoemen, Samy Abdelkader Khodeir, Ahmed Nabil Zaki, Maha Kassab, Sabry Abou-Saif and Sherief Abd-Elsalam*


DOI: 10.2174/1871530318666180716100543



Most Accessed Articles



The Assessment of Some Metabolic Markers by Combination of Ursolic Acid Supplementation and Resistance Training in Young Older Obese Women

, 2021; 21(10): 1912-1919.

Ehsan Asghari, Seyyed Reza Attarzadeh Hosseini, Mina Kiania, Tahereh Farkhondeh, Hamid Arazi and Saeed Samarghandian*


DOI: 10.2174/1871530320666201208105844


Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome

, 2021; 21(10): 1920-1928.

Raida Khalil, Wajdy J. Al-Awaida, Hamzeh J. Al-Ameer*, Yazun Jarrar, Amer Imraish, Omar Al bawareed, Rand Qawadri, Farah Al Madhoon and Loiy Obeidat


DOI: 10.2174/1871530321666201223104622




Safety and Efficacy of Teplizumab for Treatment of Type One Diabetes Mellitus: A Systematic Review and Meta-Analysis

, 2021; 21(10): 1895-1904.

Anas Zakarya Nourelden, Alaa Ahmed Elshanbary, Loalo'a El-Sherif, Amira Yasmine Benmelouka, Hagar Ismail Rohim, Sara Kamel Helmy, Merhan Kamal Sayed, Ammar Ismail, Ahmed Said Ali, Khaled Mohamed Ragab and Mohamed Sayed Zaazouee*


DOI: 10.2174/1871530320999201209222921



The Potential Role of Pro-Inflammatory and Anti-Inflammatory Cytokines in Epilepsy Pathogenesis

, 2021; 21(10): 1760-1774.

Ali N. Kamali, Zeineb Zian, José M. Bautista, Haleh Hamedifar, Nikoo Hossein-Khannazer, Ramin Hosseinzadeh, Reza Yazdani and Gholamreza Azizi*


DOI: 10.2174/1871530320999201116200940




How Much Vitamin D is Too Much? A Case Report and Review of the Literature

, 2021; 21(9): 1653-1659.

Sara De Vincentis*, Antonino Russo, Marta Milazzo, Amedeo Lonardo, Maria C. De Santis, Vincenzo Rochira, Manuela Simoni and Bruno Madeo


DOI: 10.2174/1871530320666201007152230


Hypersensitivity to Vitamins with a Focus on Immediate-Type Reactions: Food or Drug Allergy?

, 2021; 21(10): 1804-1816.

Gianfranco Calogiuri*, Lene H. Garvey, Eustachio Nettis, Francesco Casciaro, Shirina Alsowaidi, Caterina Foti and Angelo Vacca


DOI: 10.2174/1871530321666201223103411



Berberine in the Treatment of Diabetes Mellitus: A Review

, 2021; 21(8): 1379-1386.

Aleksandra Baska*, Kamil Leis and Przemysław Gałązka


DOI: 10.2174/1568026620666201022144405




Editor-in-Chief

graphic
Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

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