Bentham Science Logo
Journal Cover

Track Your Manuscript:


Endocrine, Metabolic & Immune Disorders - Drug Targets

Formerly: Current Drug Targets - Immune, Endocrine & Metabolic Disorders

Volume 21, 12 Issues, 2021
ISSN: 2212-3873 (Online)
ISSN: 1871-5303 (Print)
This journal supports open access

Aims & Scope

This journal is devoted to full-length/ mini reviews and original articles of experimental and clinical studies in the field of endocrine, metabolic, and immune disorders. Specific emphasis is placed on humoral and cellular targets for natural, synthetic, and genetically engineered drugs that enhance or impair endocrine, metabolic, and immune parameters and functions. Moreover, the topics related to the effects of food components and/or nutraceuticals on the endocrine-metabolic-immune axis and on microbioma composition are welcome.

Endocrine, Metabolic & Immune Disorders - Drug Targets

,

Volume 21

-

Number 3



Review Article (Mini-Review)



Review Article (Mini-Review)

Thrombopoietin Receptor Agonists in Children with Immune Thrombocytopenia: A New Therapeutic Era

, 21(3): 397 - 406

Giuseppe Lassandro, Valentina Palladino, Giovanni C.D. Vecchio, Viviana V. Palmieri, Paola C. Corallo, Maria F. Faienza and Paola Giordano*


DOI: 10.2174/1871530320666200531142244


Review Article



Review Article





Research Article

Association between ABCC8 Ala1369Ser Polymorphism (rs757110 T/G) and Type 2 Diabetes Risk in an Iranian Population: A Case-Control Study

, 21(3): 441 - 447

Amin Bakhtiyari, Karimeh Haghani, Salar Bakhtiyari*, Mohammad A. Zaimy, Nooriali Zahed, Ali Gheysarzadeh, Shahram Darabi, Seidali Nahalkhani, Mansour Amraei and Iraj Alipourfard


DOI: 10.2174/1871530320666200713091827


Research Article

A Retrospective Cohort Study of Histology-Proven Neuroendocrine Neoplasms in the Italian Area of Udine

, 21(3): 448 - 457

Francesca Valent*, Annarita Tullio, Elda Kara, Claudia Cipri, Silvia M. Sciannimanico, Fabio Vescini and Franco Grimaldi


DOI: 10.2174/1871530320666200713093533




Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 21 (2021) - Number 5


This issue is in progress but contains articles that are final and fully citable.

Endocrine, Metabolic & Immune Disorders - Drug Targets, Volume 21 (2021) - Number 4


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print




Hidden Hunger of Vitamin E Among Healthy College Students: A Cross- Sectional Study


Zhongqi Wan, Li Wang, Yinyang Xu, Yuanyuan Wang, Tianyou Zhang, Xinlan Mao, Qiao Li, Yangzhi Zhu, Ming Zhou* and Zhong Li


DOI: 10.2174/1871530321666210101165648
View Abstract View on PubMed


Two Cases of Double Pituitary Adenomas in a Surgical Series over 16 Years in a Single Centre


Luca Damiani*, Luca Riccioni, Daniele Nuzzi, Mariella Celico, Riccardo Panzacchi, Cecilia Ragazzini, Luigino Tosatto, Maria Teresa Nasi and Antonio Balestrieri


DOI: 10.2174/1871530321666210203213758
View Abstract View on PubMed


Appraisal of Anti-Arthritic and Anti-Inflammatory Potential of Folkloric Medicinal Plant Peganum Harmala


Muhammad Furqan Akhtar*, Syed Ahmad Raza, Ammara Saleem*, Irfan Hamid, Mirza Muhammad Faran Ashraf Baig, Ali Sharif, Kashif Sohail, Zeeshan Javaid, Uzma Saleem and Azhar Rasul


DOI: 10.2174/1871530321666210208211310
View Abstract View on PubMed



Immunopathology of Type 1 Diabetes and Immunomodulatory Effects of Stem Cells: A Narrative Review of the Literature


Ali Tootee*, Behrouz Nikbin, Aziz Ghahary, Ensieh Nasli Esfahani, Babak Arjmand, Hamidreza Aghayan, Mostafa Qorbani and Bagher Larijani*


DOI: 10.2174/1871530321666210203212809
View Abstract View on PubMed


Hypersensitivity to Vitamins with a Focus on Immediate-Type Reactions: Food or Drug Allergy?


Calogiuri Gianfranco*, Lene H. Garvey, Eustachio Nettis, Francesco Casciaro, Shirina Alsowaidi, Caterina Foti and Angelo Vacca


DOI: 10.2174/1871530321666201223103411
View Abstract View on PubMed


Dietary Intakes and Food Habits of Wheelchair Basketball Athletes Compared to Gym Attendees and Individuals who do not Practice Sport Activity


Elisabetta Toti, Valentina Cavedon, Anna Raguzzini, Anna Lucia Fedullo, Chiara Milanese, Elisabetta Bernardi, Sheila Bellito, Marco Bernardi, Tommaso Sciarra and Ilaria Peluso*


DOI: 10.2174/1871530321666210208213046
View Abstract View on PubMed


Abstracts Ahead of Print


Endocrine-Disrupting Chemicals: Introduction to the Theme


Giuseppe Lisco, Vito Angelo Giagulli, Michele Iovino, Edoardo Guastamacchia, Giovanni De Pergola and Vincenzo Triggiani*


DOI: 10.2174/1871530321666210413124425
View Abstract



The Biochemical Parameters and Vitamin D Levels in ICU Patients with Covid-19: A Cross-Sectional Study


Hamed Abdollahi, Farahnaz Salehinia, Mostafa Badeli, Elmira Karimi, Hossein Gandomkar, Amin Asadollahi, Mohsen Sedighiyan and Mina Abdolahi*


DOI: 10.2174/1871530321666210316103403
View Abstract



The Potential of T Cell Immunoglobulin and Mucin-Domain containing-3 (Tim-3) in Designing Novel Immunotherapy for Bladder Cancer


Monireh Mohsenzadegan, Parizad Bavandpour, Mohammad Reza Nowroozi, Erfan Amini, Masoumeh Kourosh-Arami, Seyed Ali Momeni, Saied Bokaie and Laleh Sharifi*


DOI: 10.2174/1871530321666210310142141
View Abstract



Association of Metabolic Syndrome and Asthma Status; A Prospective Study from Guilan Province-Iran.


Fatemeh Nejatifar, Ali Alavi Foumani, Ahmad Reza Ghorban Poor and Azita Tangestani Nejad*


DOI: 10.2174/1871530321666210305125059
View Abstract



Novel Variants of DOCK8 Deficiency in a Case Series of Iranian Patients


Sara Momtazmanesh, Elham Rayzan, Samaneh Zoghi, Sepideh Shahkarami, Rasol Molatefi, Iraj Mohammadzadeh, Javad Ghaffari, Hamidreza Mahmoudi, Jasmin Dmytrus, Anna Segarra-Roca, Ido Somekh, Maximilian Witzel, Fabian Hauck, Kaan Boztug, Christoph Klein and Nima Rezaei*


DOI: 10.2174/1871530321666210226143912
View Abstract


Published Contents

Editor's Choice

T Cell Proliferative Responses and IgG Antibodies to β2GPI in Patients with Diabetes and Atherosclerosis

, 2021; 21(3): 495 - 503

Mohammad R. Monjezi, Hamed Fouladseresht, Shirin Farjadian, Behrouz Gharesi-Fard, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530320666200505115850



Positive Correlation between Circulating Fetuin-A and Severity of Coronary Artery Disease in Men

, 2021; 21(2): 338 - 344

Reza Afrisham, Maliheh Paknejad, Davod Ilbeigi, Sahar Sadegh-Nejadi, Sattar Gorgani-Firuzjaee* and Mahmoud Vahidi*


DOI: 10.2174/1871530320666200601164253




Time-Dependent Effects in Chronic Urticaria: A Time-Series Perspective of Omalizumab Treatment

, 2020; 20(10): 1726 - 1739

Anna Tagka*, George I. Lambrou, Michael Makris, Evangelia Nakou, Electra Nicolaidou , Argyro Chatziioannou and Alexandra Katsarou


DOI: 10.2174/1871530320666200313151720




Modulation of Small Artery Function by Insulin in Young Women: Role of Adiposity

, 2020; 20(8): 1244 - 1252

Moulinath Banerjee*, Linda Shaw, Valentyn Charlton-Menys, Phillip Pemberton, Rayaz Ahmed Malik, John Kennedy Cruickshank and Clare Elizabeth Austin


DOI: 10.2174/1871530320666200428111924




Interleukin 1-beta is Linked to Chronic Low-Grade Inflammation and Cardiovascular Risk Factors in Overweight Adolescents

, 2020; 20(6): 887 - 894

Gisele A. Amaral, Josilene D. Alves, Adenilda C. Honorio-França, Danny L. Fagundes, Gabriel Gomes Araujo, Nubia S. Lobato, Victor V. Lima and Fernanda R. Giachini*


DOI: 10.2174/1871530319666191116141159



Insulin Resistance in Apolipoprotein M Knockout Mice is Mediated by the Protein Kinase Akt Signaling Pathway

, 2020; 20(5): 771 - 780

Shuang Yao, Jun Zhang, Yuxia Zhan, Yuanping Shi, Yang Yu, Lu Zheng, Ning Xu* and Guanghua Luo*


DOI: 10.2174/1871530319666191023125820




Open Access Articles

Evaluation of Gamma Amino Butyric Acid (GABA) and Glibenclamide Combination Therapy in Streptozotocin Induced Diabetes

, 2021; 21: 1 - 12 (E-Pub Ahead of Print)

Yunfeng Zhu, Sushma Devi*, Manish Kumar*, Randhir Singh Dahiya and Tarkeshwer




The Skeletal Effects of Gonadotropin-Releasing Hormone Antagonists: A Concise Review

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman and Kok-Yong Chin*




Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome

, 2021; 21: 1 - 9 (E-Pub Ahead of Print)

Raida Khalil, Wajdy J. Al-Awaida, Hamzeh J. Al-Ameer*, Yazun Jarrar, Amer Imraish, Omar Al bawareed, Rand Qawadri, Farah Al Madhoon and Loiy Obeidat





Hidden Hunger of Vitamin E Among Healthy College Students: A Cross- Sectional Study

, 2021; 21: 1 - 6 (E-Pub Ahead of Print)

Zhongqi Wan, Li Wang, Yinyang Xu, Yuanyuan Wang, Tianyou Zhang, Xinlan Mao, Qiao Li, Yangzhi Zhu, Ming Zhou* and Zhong Li




Post-Exercise Ketosis, Salivary Uric Acid and Interleukin-6 after a Simulated Wheelchair Basketball Match

, 2021; 21: 1 - 8 (E-Pub Ahead of Print)

Anna Raguzzini, Elisabetta Toti, Marco Bernardi, Fabio Castellucci, Valentina Cavedon, Anna Lucia Fedullo, Chiara Milanese, Tommaso Sciarra and Ilaria Peluso*





Appraisal of Anti-Arthritic and Anti-Inflammatory Potential of Folkloric Medicinal Plant Peganum Harmala

, 2021; 21: 1 - 15 (E-Pub Ahead of Print)

Muhammad Furqan Akhtar*, Syed Ahmad Raza, Ammara Saleem*, Irfan Hamid, Mirza Muhammad Faran Ashraf Baig, Ali Sharif, Kashif Sohail, Zeeshan Javaid, Uzma Saleem and Azhar Rasul




Dietary Intakes and Food Habits of Wheelchair Basketball Athletes Compared to Gym Attendees and Individuals who do not Practice Sport Activity

, 2021; 21: 1 - 11 (E-Pub Ahead of Print)

Elisabetta Toti, Valentina Cavedon, Anna Raguzzini, Anna Lucia Fedullo, Chiara Milanese, Elisabetta Bernardi, Sheila Bellito, Marco Bernardi, Tommaso Sciarra and Ilaria Peluso*




Effects of a Low Carb Diet and Whey Proteins on Anthropometric, Hematochemical, and Cardiovascular Parameters in Subjects with Obesity

, 2020; 20(10): 1719 - 1725

Giovanni De Pergola*, Roberta Zupo, Luisa Lampignano, Silvia Paradiso, Isanna Murro, Annagrazia Cecere, Nicola Bartolomeo, Marco M. Ciccone, Gianluigi Giannelli and Vincenzo Triggiani





The Association between Peripheral Blood Cells and the Frailty Syndrome in Patients with Cardiovascular Diseases

, 2020; 20(9): 1419 - 1433

Constantin Bodolea, Elisabeta I. Hiriscau*, Elena-Cristina Buzdugan, Alin I. Grosu, Laurențiu Stoicescu, Ștefan Vesa and Omar Cauli




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 2: Therapeutic Issues

, 2020; 20(8): 1144 - 1155

Renato Cozzi*, Maria R. Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso, Pietro Maffei, Maurizio Poggi, Vincenzo Toscano, Michele Zini, Philippe Chanson and Laurence Katznelson




Italian Association of Clinical Endocrinologists (AME) and Italian AACE Chapter Position Statement for Clinical Practice: Acromegaly - Part 1: Diagnostic and Clinical Issues

, 2020; 20(8): 1133 - 1143

Renato Cozzi*, Maria R. Ambrosio, Roberto Attanasio, Alessandro Bozzao, Laura De Marinis, Ernesto De Menis, Edoardo Guastamacchia, Andrea Lania, Giovanni Lasio, Francesco Logoluso, Pietro Maffei, Maurizio Poggi, Vincenzo Toscano, Michele Zini, Philippe Chanson and Laurence Katznelson






Most Cited Articles


Research Article

Predictors for fibrosis regression in chronic HCV patients after the treatment with DAAS: Results of a real-world cohort study

, 2020; 20(1): 104-111.

Hanan Soliman, Dina Ziada, Marwa Salama, Manal Hamisa, Rehab Badawi, Nehad Hawash, Amal Selim and Sherief Abd-Elsalam*


DOI: 10.2174/1871530319666190826150344


Review Article (Mini-Review)

Quality of life in individuals with diabetic foot syndrome

, 2020; 20(9): 1365-1372.

Emmanuel Navarro-Flores and Omar Cauli*


DOI: 10.2174/1871530320666200128154036


Review Article

The biochemical and clinical perspectives of lactate dehydrogenase: An enzyme of active metabolism

, 2020; 20(6): 855-868.

Amjad A. Khan*, Khaled S. Allemailem, Fahad A. Alhumaydhi, Sivakumar J.T. Gowder and Arshad H. Rahmani


DOI: 10.2174/1871530320666191230141110


Review Article

Peripheral immunosenescence and central neuroinflammation: A dangerous liaison - A dietary approach

, 2020; 20(9): 1391-1411.

Thea Magrone*, Manrico Magrone, Matteo A. Russo and Emilio Jirillo


DOI: 10.2174/1871530320666200406123734


Research Article

The preventive effect of IL-1beta antagonist on diabetic peripheral neuropathy

, 2020; 20(5): 753-759.

Zheng Hangping , Han Ling, Ji Lijin, Zhao Wenting, Liu Xiaoxia, Zhang Qi, Zhu Xiaoming, Li Qingchun, Li Yiming, Xiong Qian, Hu Ji, Lu Bin* and Zhang Shuo*


DOI: 10.2174/1871530319666191022114139


Review Article

Our little friends with big roles: Alterations of the gut microbiota in thyroid disorders

, 2020; 20(3): 344-350.

Hanieh-Sadat Ejtahed, Pooneh Angoorani, Ahmad-Reza Soroush, Seyed-Davar Siadat, Nooshin Shirzad, Shirin Hasani-Ranjbar* and Bagher Larijani


DOI: 10.2174/1871530319666190930110605


Research Article

Anti-cancerous effect of rutin against HPV-C33A cervical cancer cells via g0/g1 cell cycle arrest and apoptotic induction

, 2020; 20(3): 409-418.

Fahad Khan, Pratibha Pandey*, Tarun K. Upadhyay, Asif Jafri, Niraj K. Jha, Rashmi Mishra and Vineeta Singh


DOI: 10.2174/1871530319666190806122257


Review Article

Molecular and immunological mechanisms underlying the various pharmacological properties of the potent bioflavonoid, rutin

, 2020; 20(10): 1590-1596.

David O.C. Yong, Sanggetha R. Saker, Dinesh K. Chellappan*, Thiagarajan Madheswaran, Jithendra Panneerselvam, Hira Choudhury, Manisha Pandey, Yik L. Chan, Trudi Collet, Gaurav Gupta, Brian G. Oliver, Peter Wark, Nicole Hansbro, Alan Hsu, Philip M. Hansbro, Kamal Dua* and Farrukh Zeeshan


DOI: 10.2174/1871530320666200503053846



Review Article

Immune-inflammation in atherosclerosis: A new twist in an old tale

, 2020; 20(4): 525-545.

Atefe Ghamar Talepoor, Hamed Fouladseresht, Shahdad Khosropanah and Mehrnoosh Doroudchi*


DOI: 10.2174/1871530319666191016095725


Systematic Review Article

The association of metabolic syndrome and psoriasis: A systematic review and meta-analysis of observational study

, 2020; 20(5): 703-717.

Saumya Choudhary, Dibyabhaba Pradhan, Anamika Pandey, Mohd. Kamran Khan, Rohit Lall, V. Ramesh, Poonam Puri, Arun K. Jain* and George Thomas*


DOI: 10.2174/1871530319666191008170409


Review Article

Diagnostic approach to the patients with suspected primary immunodeficiency

, 2020; 20(2): 157-171.

Marzieh Tavakol, Mahnaz Jamee, Gholamreza Azizi*, Homa Sadri, Yasser Bagheri, Majid Zaki-Dizaji, Fatemeh Sadat Mahdavi, Farhad Jadidi-Niaragh, Sanaz Tajfirooz, Ali N. Kamali, Fatemeh Aghamahdi, Shahab Noorian, Habibeh Taghavi Kojidi, Mehdi Mosavian, Rahman Matani, Elahe Dolatshahi, Kumars Porrostami, Nasrin Elahimehr, Marzie Fatemi-Abhari, Laleh Sharifi, Reza Arjmand, Sabahat Haghi, Hamed Zainaldain, Reza Yazdani, Mohammadreza Shaghaghi, Hassan Abolhassani and Asghar Aghamohammadi


DOI: 10.2174/1871530319666190828125316


Review Article

Lncrna, important player in bone development and disease

, 2020; 20(1): 50-66.

Dijie Li, Chaofei Yang, Chong Yin, Fan Zhao, Zhihao Chen, Ye Tian, Kai Dang, Shanfeng Jiang, Wenjuan Zhang, Ge Zhang and Airong Qian*


DOI: 10.2174/1871530319666190904161707


Review Article

The “scourge of the renaissance”. A short review about treponema pallidum infection

, 2020; 20(3): 335-343.

Luigi Santacroce*, Lucrezia Bottalico*, Skender Topi, Francesca Castellaneta and Ioannis A. Charitos


DOI: 10.2174/1871530319666191009144217



Most Accessed Articles



SIRT1: Mechanism and Protective in Diabetic Nephropathy

, 2021; 21(5): 835-842.

Jing Ji, Pengyu Tao, Qian Wang, Lingxing Li and Yuzhen Xu*


DOI: 10.2174/1871530320666201029143606


Rebalancing the Oral Microbiota as an Efficient Tool in Endocrine, Metabolic, and Immune Disorders

, 2021; 21(5): 777-784.

Ciro Gargiulo Isacco, Andrea Ballini *, Danila De Vito, Kieu Cao Diem Nguyen, Stefania Cantore, Lucrezia Bottalico, Lucio Quagliuolo, Mariarosaria Boccellino, Marina Di Domenico, Luigi Santacroce, Roberto Arrigoni, Gianna Dipalma and Francesco Inchingolo


DOI: 10.2174/1871530320666200729142504


Dyslipidemia Management in 2020: An Update on Diagnosis and Therapeutic Perspectives

, 2021; 21(5): 815-834.

Ioannis D. Karantas*, Mehmet E. Okur*, Neslihan Ü. Okur and Panoraia I. Siafaka


DOI: 10.2174/1871530320666200810144004


Immune and Metabolic Interactions of Human Erythrocytes: A Molecular Perspective

, 2021; 21(5): 843-853.

Charalampos Papadopoulos, Maria Panopoulou, Konstantinos Anagnostopoulos* and Ioannis Tentes


DOI: 10.2174/1871530320666201104115016


Determination of the Upper Reference Limit of Human Epididymis Secretory Protein 4 (HE4) in Healthy Male Individuals and Correlation with Renal and Fertility Markers

, 2021; 21(5): 912-918.

Annalisa Schirinzi, Angela Pia Cazzolla, Elisa Mascolo, Giuseppe Palmieri, Francesco Pesce, Loreto Gesualdo, Luigi Santacroce, Andrea Ballini *, Roberto Lovero and Francesca Di Serio


DOI: 10.2174/1871530320666200807121050


Different Pharmacokinetic Responses to an Acute Dose of Inorganic Nitrate in Patients with Type 2 Diabetes

, 2021; 21(5): 878-886.

Zahra Bahadoran, Parvin Mirmiran, Mattias Carlström, Reza Norouzirad, Sajad Jeddi, Fereidoun Azizi and Asghar Ghasemi*


DOI: 10.2174/1871530320666200813135251



What is the Impact of Cinnamon Supplementation on Blood Pressure? A Systematic Review and Meta-Analysis

, 2021; 21(5): 956-965.

Abed Ghavami, Hossein K. Haghighian, Neda Roshanravan, Rahele Ziaei, Ehsan Ghaedi*, Amir R. Moravejolahkami and Gholamreza Askari*


DOI: 10.2174/1871530320666200729143614


Comparison of the Effect of Adipocyte-derived Stem Cells and Curcumin Nanoliposomes with Phenytoin on Open Cutaneous Wound Healing in Rats

, 2021; 21(5): 866-877.

Mohammadreza Ebrahimzade, Mohammad Mirdoraghi, Ameneh Alikarami, Sahar Heidari, Tayebeh Rastegar, Ali R. Partoazar and Nasrin Takzaree*


DOI: 10.2174/1871530320999200817172200


The Effects of Pemafibrate in Japanese Patients with Type 2 Diabetes Receiving HMG-CoA Reductase Inhibitors

, 2021; 21(5): 919-924.

Masataka Kusunoki*, Takahiko Sakazaki, Kazuhiko Tsutsumi, Tetsuro Miyata and Yoshiharu Oshida


DOI: 10.2174/1871530320999200818135553


Antihyperglycemic Activity of Micromeria Graeca Aqueous Extract in Streptozotocin-Induced Diabetic Rats

, 2021; 21(5): 887-894.

Mourad Akdad, Amine Azzane, Fadwa El Ouady, Abdelhadi Moujani, Farid El Khallouki and Mohamed Eddouks*


DOI: 10.2174/1871530320666200807124940



Vitamin D Receptor Gene Polymorphisms and the Risk of Metabolic Syndrome (MetS): A Meta-Analysis

, 2021; 21(5): 943-955.

Hamidreza Totonchi, Ramazan Rezaei, Shokoofe Noori, Negar Azarpira*, Pooneh Mokarram* and Danyal Imani


DOI: 10.2174/1871530320666200805101302




Editor-in-Chief

graphic
Emilio Jirillo
Department of Basic Medical Sciences Neuroscience and Sensory Organs
University of Bari “Aldo Moro”
Bari
(Italy)
Biography
View Full Editorial Board

COPE Compliant

Cope Logo

Journal History

Current Drug Targets - Immune, Endocrine & Metabolic Disorders was launched in 2001 and later renamed in 2006 as Endocrine, Metabolic & Immune Disorders - Drug Targets.

Related Journals

Related eBooks

eBooks Catalog