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Mini-Reviews in Medicinal Chemistry

Volume 21, 20 Issues, 2021
ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)
This journal supports open access

Aims & Scope

The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry including developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to be kept informed and up-to-date with the latest and most important developments.

Mini-Reviews in Medicinal Chemistry

,

Volume 21

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Number 18





Editorial   Open Access

Natural Products Databases for Drug Design

, 21(18): 2628 - 2629

Luciana Scotti , Marcus T. Scotti and Eugene Muratov


DOI: 10.2174/138955752118210824095236


Review Article

Anti-aging Natural Compounds and their Role in the Regulation of Metabolic Pathways Leading to Longevity

, 21(18): 2630 - 2656

Aqsa Muzammil, Muhammad Waqas, Ahitsham Umar, Muhammad Sufyan, Abdur Rehman, Ali Haider, Haseeb Akram, Seemab Amjad Fateh Khan, Muhammad Afzal, Muhammad Wajid, Rana Adnan Tahir and Sheikh Arslan Sehgal*


DOI: 10.2174/1389557521666210405162006


Review Article

Virtual Screening of Natural Products Database

, 21(18): 2657 - 2730

José Alixandre de Sousa Luis, Renata Priscila Costa Barros, Natália Ferreira de Sousa, Eugene Muratov, Luciana Scotti and Marcus Tullius Scotti*


DOI: 10.2174/1389557520666200730161549




Review Article

Osthole: A Multifunctional Natural Compound with Potential Anticancer, Antioxidant and Anti-inflammatory Activities

, 21(18): 2747 - 2763

Saba Zafar, Iqra Sarfraz, Azhar Rasul*, Muhammad Ajmal Shah*, Ghulam Hussain, Muhammad Kashif Zahoor, Nusrat Shafiq, Ammara Riaz, Zeliha Selamoglu and Satyajit D. Sarker


DOI: 10.2174/1389557520666200709175948






Mini-Reviews in Medicinal Chemistry, Volume 21 (2021) - Number 19


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Ziziphus oenoplia Mill.: A Systematic Review on Ethnopharmacology, Phytochemistry and Pharmacology of an Important Traditional Medicinal Plant


Afsana Nahrin, Md. Junaid, Syeda Samira Afrose, Antica Barua, Yeasmin Akter, Muhammad Shaiful Alam, Tania Sharmin*, Sakia Ferdousy and S. M. Zahid Hosen


DOI: 10.2174/1389557521666210810153311
View Abstract


Carbohydrazide Analogues: A Review of Synthesis and Biological Activities


Ebuka Leonard Onyeyilim*, Mercy Amarachi Ezeokonkwo, David Izuchukwu Ugwu, Chiamaka Peace Uzoewulu , Florence Uchenna Eze, Vivian Ifeoma Okonkwo, Cosmas Chinweike Eze and James Anayochukwu Ezugwu


DOI: 10.2174/1389557521666210831154935
View Abstract View on PubMed


Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-Analysis of Clinical Trials


Reza Tabrizi, Eghbal Sekhavati, Peyman Nowrouzi-Sohrabi, Shahla Rezaei, Parinaz Tabari, Salar Hafez Ghoran, Navid Jamali, Mohammad Jalali, Mahsa Moosavi, Ali-Asghar Kolahi, Deepti Bettampadi, Amirhossein Sahebkar* and Saeid Safiri *


DOI: 10.2174/1389557521666210929143112
View Abstract View on PubMed


Nature-Derived Hit, Lead, and Drug-Like Small Molecules: Current Status and Future Aspects against Key Target Proteins of Coronaviruses


Md. Junaid*, Yeasmin Akter, Aysha Siddika, S. M. Abdul Nayeem, Afsana Nahrin, Syeda Samira Afrose, Md. Muzahid Ahmed Ezaj and Muhammad Shaiful Alam


DOI: 10.2174/1389557521666210805113231
View Abstract View on PubMed



Electrospinning: New Strategies for the Treatment of Skin Melanoma


Javier Mauricio Anaya Mancipe*, Franz Acker Lobianco, Marcos Lopes Dias and Rossana Mara da Silva Moreira Thiré


DOI: 10.2174/1389557521666210712111809
View Abstract View on PubMed


Advances in Anti-inflammatory Activity, Mechanism and Therapeutic Application of Ursolic Acid


Mingzhu Luan, Huiyun Wang, Jiazhen Wang, Xiaofan Zhang, Fenglan Zhao, Zongliang Liu and Qingguo Meng*


DOI: 10.2174/1389557521666210913113522
View Abstract View on PubMed



New Scope of Targeted Therapies in Lung Carcinoma


Archana Sonkar, Pranesh Kumar, Anurag Gautam, Biswanath Maity and Sudipta Saha*


DOI: 10.2174/1389557521666210805104714
View Abstract View on PubMed


Abstracts Ahead of Print


The Use of Textiles in the Wound Healing: A Review


Janaína Ribeiro Oliveira, Victor Hugo Dantas Guimarães, Ulisses Alves Pereira, Fernando Ribeiro Oliveira and Sérgio Henrique Sousa Santos*


DOI: 10.2174/1389557521666211124142553
View Abstract


Chromone a Privileged Scaffold in Drug Discovery: Developments on the Synthesis and Bioactivity


Anjitha Theres Benny, Sonia D. Arikkatt , Cijo George Vazhappilly, Sathananthan Kannadasan, Renjan Thomas, Manju Sreedharan Nair Leelabaiamma, Ethiraj Kannatt Radhakrishnan* and Ponnusamy Shanmugam


DOI: 10.2174/1389557521666211124141859
View Abstract


In Vivo Acute Anti-Inflammatory Activity of Essential Oils: A Review


Letícia Groli Lucca, Pedro Roosevelt Torres Romão, Márcia Vignoli-Silva, Valdir F. da Veiga-Junior and Letícia S. Koester*


DOI: 10.2174/1389557521666211123091541
View Abstract


An Insight into the Polymeric Nanoparticles Applications in Diabetes Diagnosis and Treatment


Parisa Dehghani, Monireh Esameili Rad, Atefeh Zarepour, Ponnurengam Malliappan Sivakumar* and Ali Zarrabi*


DOI: 10.2174/1389557521666211116123002
View Abstract




Therapeutic Journey and Recent Advances in the Synthesis of Coumarin Derivatives


Shweta Sinha , Kuldeep Singh*, Akash Ved, Syed Misbahul Hasan and Samar Mujeeb


DOI: 10.2174/1389557521666211116120823
View Abstract




Published Contents

Editor's Choice

Therapeutic Potential of Resveratrol in the Treatment of Glioma: Insights into its Regulatory Mechanisms

, 2021; 21(18): 2835 - 2847

Ehsan Dadgostar, Maryam Fallah, Fatemeh Izadfar, Reza Heidari-Soureshjani, Michael Aschner, Omid Reza Tamtaji* and Hamed Mirzaei*


DOI: 10.2174/1389557521666210406164758



Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity

, 2021; 21(17): 2420 - 2457

Priyanka Joshi, Sushil Joshi, Deepak Semwal, Akansha Bisht, Sarvesh Paliwal, Jaya Dwivedi and Swapnil Sharma*


DOI: 10.2174/1389557521666210122153823





Mediterranean Diet Polyphenols: Anthocyanins and Their Implications for Health

, 2021; 21(13): 1692 - 1700

Simona Martinotti, Gregorio Bonsignore, Mauro Patrone and Elia Ranzato*


DOI: 10.2174/1389557521999201230200813





Resistance to Intervention: Paclitaxel in Breast Cancer

, 2021; 21(10): 1237 - 1268

Vipin Mohan Dan, Reji Saradha Raveendran and Sabulal Baby*


DOI: 10.2174/1389557520999201214234421





Open Access Articles

Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables

, 2019; 19(4): 310 - 332

Lucia Pacifico, John F. Osborn, Enea Bonci, Pasquale Pierimarchi and Claudio Chiesa*




Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684 - 1701

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*




Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

, 2018; 18(2): 173 - 183

Voon Yee-Lin*, Wong Pooi-Fong and Alan Khoo Soo-Beng






G4 Aptamers: Trends in Structural Design

, 2016; 16(16): 1321 - 1329

Anna Varizhuk, Nikolay Ilyinsky, Igor Smirnov and Galina Pozmogova






Augmentation of Creatine in the Heart

, 2016; 16(1): 19 - 28

Sevasti Zervou, Hannah J. Whittington, Angela J. Russell and Craig A. Lygate





Intramolecular Immunological Signal Hypothesis Revived - Structural Background of Signalling Revealed by Using Congo Red as a Specific Tool

, 2014; 14(13): 1104 - 1113

A. Jagusiak, L. Konieczny, M. Krol, P. Marszalek, B. Piekarska, P. Piwowar, I. Roterman, J. Rybarska, B. Stopa and G. Zemanek





Attachment of Rod-Like (BAR) Proteins and Membrane Shape

, 2011; 11(4): 272 - 282

D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic and A. Iglic







Most Cited Articles

Review Article

Research progress of glycyrrhizic acid on antiviral activity

, 2019; 19(10): 826-832.

Zhi-Gang Sun*, Ting-Ting Zhao, Na Lu, Yong-An Yang and Hai-Liang Zhu*


DOI: 10.2174/1389557519666190119111125


Review Article

Radicals, oxidative/nitrosative stress and preeclampsia

, 2019; 19(3): 178-193.

Seyithan Taysi*, Ayse Saglam Tascan, Mete Gurol Ugur and Mustafa Demir


DOI: 10.2174/1389557518666181015151350



Systemic Review Article

Pharmacological aspects and potential use of phloretin: A systemic review

, 2019; 19(13): 1060-1067.

Arokia V.A. Mariadoss*, Ramachandran Vinyagam, Vinothkumar Rajamanickam, Vijayalakshmi Sankaran, Sathish Venkatesan and Ernest David*


DOI: 10.2174/1389557519666190311154425


Systemic Review Article

Clinical management of oral lichen planus: A systematic review

, 2019; 19(13): 1049-1059.

Luca Oberti, Lucchese Alberta, Petruzzi Massimo, Carinci Francesco and Lauritano Dorina*


DOI: 10.2174/1389557519666190301144157


Review Article

A review exploring therapeutic worth of 1,3,4-Oxadiazole tailored compounds

, 2019; 19(6): 477-509.

Garima Verma, Mohemmed F. Khan, Wasim Akhtar, Mohammad Mumtaz Alam, Mymoona Akhter and Mohammad Shaquiquzzaman*


DOI: 10.2174/1389557518666181015152433


Review Article

Protective role of natural products in cisplatin-induced nephrotoxicity

, 2019; 19(14): 1134-1143.

Nurul Raudzah Adib Ridzuan, Norhashima Abd Rashid, Faizah Othman, Siti Balkis Budin, Farida Hussan and Seong Lin Teoh*


DOI: 10.2174/1389557519666190320124438


Review Article

A review on anticancer potentials of benzothiazole derivatives

, 2020; 20(1): 12-23.

Nandini Pathak, Ekta Rathi, Nitesh Kumar*, Suvarna G. Kini and C. Mallikarjuna Rao


DOI: 10.2174/1389557519666190617153213


Review Article

A review on quinoline derived scaffolds as anti-HIV agents

, 2019; 19(6): 510-526.

Nisha Chokkar, Sourav Kalra, Monika Chauhan and Raj Kumar*


DOI: 10.2174/1389557518666181018163448


Review Article

Benzimidazole: A milestone in the field of medicinal chemistry

, 2020; 20(7): 532-565.

Mahesh S. Vasava, Manoj N. Bhoi, Sanjay K. Rathwa, Divya J. Jethava, Prachi T. Acharya, Dhaval B. Patel and Hitesh D. Patel*


DOI: 10.2174/1389557519666191122125453



Review Article

Marine natural product bis-indole alkaloid caulerpin: Chemistry and biology

, 2019; 19(9): 751-761.

Jignesh Lunagariya, Poonam Bhadja, Shenghui Zhong, Rohit Vekariya and Shihai Xu*


DOI: 10.2174/1389557517666170927154231


General Review Article

Biological nanofactories: Using living forms for metal nanoparticle synthesis

, 2021; 21(2): 245-265.

Shilpi Srivastava, Zeba Usmani, Atanas G. Atanasov, Vinod Kumar Singh, Nagendra Pratap Singh, Ahmed M. Abdel-Azeem, Ram Prasad, Govind Gupta, Minaxi Sharma* and Atul Bhargava*


DOI: 10.2174/1389557520999201116163012


Review Article

Parkinson’s disease: A review from pathophysiology to treatment

, 2020; 20(9): 754-767.

Bianca L.B. Marino, Lucilene R. de Souza, Kessia P.A. Sousa, Jaderson V. Ferreira, Elias C. Padilha, Carlos H.T.P. da Silva, Carlton A. Taft and Lorane I.S. Hage-Melim*


DOI: 10.2174/1389557519666191104110908


Review Article

Synthesis and biological activity of hydrazones and derivatives: A review

, 2020; 20(5): 342-368.

Juliana de Oliveira Carneiro Brum*, Tanos Celmar Costa França, Steven R. LaPlante and José Daniel Figueroa Villar


DOI: 10.2174/1389557519666191014142448



Most Accessed Articles


Advancement of Natural Compounds as Anti-Rheumatoid Arthritis Agents: A Focus on Their Mechanism of Actions

, 2021; 21(19): 2957-2975.

Huanghe Yu, Yixing Qiu, Shumaila Tasneem, Muhammad Daniyal, Bin Li, Xiong Cai, Atta-ur Rahman and Wei Wang*


DOI: 10.2174/1389557521666210304112916



Effectiveness of Azithromycin as add-on Therapy in COVID-19 Management

, 2021; 21(19): 2860-2873.

Shadma Wahab*, Md Faruque Ahmad, Arshad Hussain, Shazia Usmani, Ambreen Shoaib and Wasim Ahmad


DOI: 10.2174/1389557521666210401093948




The Role of Coffee and its Bioactive Components in Platelet Function and Aging

, 2021; 21(19): 2850-2859.

Diego Arauna, Simón Navarrete, Matías Devia , Lyanne Rodríguez, Lemuel Reyes, Sergio Wehinger , Andrea Silva-Weiss, Iván Palomo* and Eduardo Fuentes *


DOI: 10.2174/1389557521666210405155859


Anti-mycobacterial Constituents from Medicinal Plants; A Review

, 2021; 21(19): 3037-3051.

Nandan Sarkar, Yadu Nandan Dey, Dharmendra Kumar * and Mogana Rajagopal


DOI: 10.2174/1389557521666210525120325


Recent Progress Towards Vaccines and Antibody-based Therapies Against Alzheimer's Disease

, 2021; 21(19): 3062-3072.

Wenbo Ji, Baofeng Gong, Hong Jin, Xiaohan Chen, Peng Li, Wenbin Cheng , Yuchen Zhao , Bin He, Jianhua Zhuang*, Jie Gao* and You Yin *


DOI: 10.2174/1389557521666210805110920



Anticancer Potential of Coumarin and its Derivatives

, 2021; 21(19): 2996-3029.

Narayan Bhattarai, Anupa A. Kumbhar, Yuba Raj Pokharel and Paras Nath Yadav*


DOI: 10.2174/1389557521666210405160323


Virtual Screening of Natural Products Database

, 2021; 21(18): 2657-2730.

José Alixandre de Sousa Luis, Renata Priscila Costa Barros, Natália Ferreira de Sousa, Eugene Muratov, Luciana Scotti and Marcus Tullius Scotti*


DOI: 10.2174/1389557520666200730161549




Osthole: A Multifunctional Natural Compound with Potential Anticancer, Antioxidant and Anti-inflammatory Activities

, 2021; 21(18): 2747-2763.

Saba Zafar, Iqra Sarfraz, Azhar Rasul*, Muhammad Ajmal Shah*, Ghulam Hussain, Muhammad Kashif Zahoor, Nusrat Shafiq, Ammara Riaz, Zeliha Selamoglu and Satyajit D. Sarker


DOI: 10.2174/1389557520666200709175948




Co-Editors

graphic
Atta-ur-Rahman, FRS
(32052 citations)
Kings College
University of Cambridge
Cambridge
(UK)
Biography
graphic
Muhammad Iqbal Choudhary
(27325 citations)
H.E.J. Research Institute of Chemistry
University of Karachi
Karachi
(Pakistan)
Biography
graphic
Alessandro Granito
University of Bologna
Diparitmento Di Scienze Mediche E Chirurgiche
Bologna
(Italy)
graphic
Davide Barreca
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences
University of Messina
Messina
(Italy)
Biography
View Full Editorial Board

COPE Compliant

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Journal History

Mini-Reviews in Medicinal Chemistry was launched in 2001. Dr. Atta-ur-Rahman, Dr. M. Iqbal Choudhary and Dr. Davide Barreca are the Co-Editors of the journal.

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