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Mini-Reviews in Medicinal Chemistry

Volume 22, 22 Issues, 2022
ISSN: 1875-5607 (Online)
ISSN: 1389-5575 (Print)
This journal supports open access

Aims & Scope

The aim of Mini-Reviews in Medicinal Chemistry is to publish short reviews on the important recent developments in medicinal chemistry and allied disciplines.

Mini-Reviews in Medicinal Chemistry covers all areas of medicinal chemistry, including quantitative structure-function relationships, synthetic chemistry, bioorganic chemistry, drug absorption, drug distribution, drug metabolism, new and emerging drug targets, pharmacogenomics, drug safety profile and drug-induced liver injury (DILI), drug discovery toxicology, high-throughput screening, combinatorial chemistry, structural characterization and organic syntheses of naturally occurring compounds, "nanosystem and nanocarriers", as well as chemical and analytical techniques used in rational drug design.

Mini-Reviews in Medicinal Chemistry is an essential journal for every medicinal and pharmaceutical chemist who wishes to remain informed and up-to-date with the latest and most important developments.

Mini-Reviews in Medicinal Chemistry

,

Volume 22

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Number 7




Review Article

Alkaloids Exhibit a Meaningful Function as Anticancer Agents by Restraining Cellular Signaling Pathways

, 22(7): 968 - 983

Wen Xu, Bei Wang, Yisong Gao, Yuxuan Cai, Jiali Zhang, Zhiyin Wu, Jiameng Wei, Chong Guo* and Chengfu Yuan*


DOI: 10.2174/1389557521666211007114935


Review Article

Discovery and Development of Antibacterial Agents: Fortuitous and Designed

, 22(7): 984 - 1029

Ravleen Kaur, Pooja Rani, Atanas G. Atanasov, Qushmua Alzahrani, Reena Gupta, Bhupinder Kapoor*, Monica Gulati* and Pooja Chawla


DOI: 10.2174/1570193X19666211221150119


Review Article

Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity

, 22(7): 1030 - 1063

Anjitha Theres Benny, Sonia D. Arikkatt , Cijo George Vazhappilly, Sathananthan Kannadasan, Renjan Thomas, Manju Sreedharan Nair Leelabaiamma, Ethiraj Kannatt Radhakrishnan* and Ponnusamy Shanmugam


DOI: 10.2174/1389557521666211124141859


Review Article

A Review on Coumarin Derivatives as Potent Anti-tuberculosis Agents

, 22(7): 1064 - 1080

Samar Mujeeb, Kuldeep Singh*, Bhumika Yogi, Vaseem Ansari and Shweta Sinha


DOI: 10.2174/1389557521666210927124511



Mini-Reviews in Medicinal Chemistry, Volume 22 (2022) - Number 9


This issue is in progress but contains articles that are final and fully citable.

Mini-Reviews in Medicinal Chemistry, Volume 22 (2022) - Number 8


This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print


Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy


Ponnurengam Malliappan Sivakumar, Pranav Kumar Prabhakar, Sibel Cetinel, Neelakandan R. and Veluchamy Prabhawathi*


DOI: 10.2174/1389557522666220309140855
View Abstract View on PubMed




Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease


Zahra Shaghaghi, Shokouh Motieian, Maryam Alvandi, Amirhossein Yazdi, Bahareh Asadzadeh, Soghra Farzipour* and Sahar Abbasi


DOI: 10.2174/1389557522666220218123404
View Abstract View on PubMed


An Update on Arginase Inhibitors and Inhibitory Assays


Jason Muller, Rym Attia, Andy Zedet, Corine Girard and Marc Pudlo*


DOI: 10.2174/1389557522666211229105703
View Abstract View on PubMed




Relationship between Gut Microbiota and Bone Health


Ke You, Lianjun Yang, Jun Shen, Bin Liu, Yuanqing Guo, Tao Chen, Guowei Li and Hai Lu*


DOI: 10.2174/1389557522666220304230920
View Abstract


Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics


Anna Carolina Schneider Alves, Raquel Soares Cardoso, Xisto Antonio de Oliveira Neto and Daniel Fábio Kawano*


DOI: 10.2174/1389557522666220309162203
View Abstract View on PubMed


Abstracts Ahead of Print

Advances and Challenges in the Investigation of Metastasis in Diffuse Large B-Cell Lymphoma


Yingying Chen*, Lingling Jiang*, Lixia Liu*, Min Ruan, Zhicheng Zhou, Mingzhen Yang and Leiming Xia*


DOI: 10.2174/1389557522666220519085134
View Abstract




A Short Review on Glucogallin and its Pharmacological Activities


Anam Najib Khan, Rajveer Singh, Arka Bhattacharya, Rudra Chakravarti, Syamal Roy*, Velayutham Ravichandiran* and Dipanjan Ghosh*


DOI: 10.2174/1389557522666220513150907
View Abstract







Potential of Phytomolecules in Sync with Nanotechnology to Surmount the Limitations of Current Treatment Options in the Management of Osteoarthritis


Atul Mourya, Shubhra, Neha Bajwa, Ashish Baldi, Kamalinder K Singh, Manisha Pandey, Shashi Bala Singh and Jitender Madan*


DOI: 10.2174/1389557522666220511140527
View Abstract


Published Contents

Editor's Choice

Therapeutic Potential of Resveratrol in the Treatment of Glioma: Insights into its Regulatory Mechanisms

, 2021; 21(18): 2835 - 2847

Ehsan Dadgostar, Maryam Fallah, Fatemeh Izadfar, Reza Heidari-Soureshjani, Michael Aschner, Omid Reza Tamtaji* and Hamed Mirzaei*


DOI: 10.2174/1389557521666210406164758



Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity

, 2021; 21(17): 2420 - 2457

Priyanka Joshi, Sushil Joshi, Deepak Semwal, Akansha Bisht, Sarvesh Paliwal, Jaya Dwivedi and Swapnil Sharma*


DOI: 10.2174/1389557521666210122153823





Mediterranean Diet Polyphenols: Anthocyanins and Their Implications for Health

, 2021; 21(13): 1692 - 1700

Simona Martinotti, Gregorio Bonsignore, Mauro Patrone and Elia Ranzato*


DOI: 10.2174/1389557521999201230200813





Resistance to Intervention: Paclitaxel in Breast Cancer

, 2021; 21(10): 1237 - 1268

Vipin Mohan Dan, Reji Saradha Raveendran and Sabulal Baby*


DOI: 10.2174/1389557520999201214234421





Open Access Articles

Aptamers Against COVID-19: An Untested Opportunity

, 2022; 22: 1 - 8 (E-Pub Ahead of Print)

Annekathrin Haberland* and Johannes Müller




Association between Vitamin D Levels and Nonalcoholic Fatty Liver Disease: Potential Confounding Variables

, 2019; 19(4): 310 - 332

Lucia Pacifico, John F. Osborn, Enea Bonci, Pasquale Pierimarchi and Claudio Chiesa*




Adenosine: Synthetic Methods of Its Derivatives and Antitumor Activity

, 2018; 18(20): 1684 - 1701

Francisco Z. Valdés, Víctor Z. Luna, Bárbara R. Arévalo, Nelson V. Brown and Margarita C. Gutiérrez*




Nutlin-3, A p53-Mdm2 Antagonist for Nasopharyngeal Carcinoma Treatment

, 2018; 18(2): 173 - 183

Voon Yee-Lin*, Wong Pooi-Fong and Alan Khoo Soo-Beng






G4 Aptamers: Trends in Structural Design

, 2016; 16(16): 1321 - 1329

Anna Varizhuk, Nikolay Ilyinsky, Igor Smirnov and Galina Pozmogova






Augmentation of Creatine in the Heart

, 2016; 16(1): 19 - 28

Sevasti Zervou, Hannah J. Whittington, Angela J. Russell and Craig A. Lygate





Intramolecular Immunological Signal Hypothesis Revived - Structural Background of Signalling Revealed by Using Congo Red as a Specific Tool

, 2014; 14(13): 1104 - 1113

A. Jagusiak, L. Konieczny, M. Krol, P. Marszalek, B. Piekarska, P. Piwowar, I. Roterman, J. Rybarska, B. Stopa and G. Zemanek




Attachment of Rod-Like (BAR) Proteins and Membrane Shape

, 2011; 11(4): 272 - 282

D. Kabaso, E. Gongadze, P. Elter, U. van Rienen, J. Gimsa, V. Kralj-Iglic and A. Iglic





Most Cited Articles

Review Article

Research progress of glycyrrhizic acid on antiviral activity

, 2019; 19(10): 826-832.

Zhi-Gang Sun*, Ting-Ting Zhao, Na Lu, Yong-An Yang and Hai-Liang Zhu*


DOI: 10.2174/1389557519666190119111125


Review Article

Radicals, oxidative/nitrosative stress and preeclampsia

, 2019; 19(3): 178-193.

Seyithan Taysi*, Ayse Saglam Tascan, Mete Gurol Ugur and Mustafa Demir


DOI: 10.2174/1389557518666181015151350



Systemic Review Article

Pharmacological aspects and potential use of phloretin: A systemic review

, 2019; 19(13): 1060-1067.

Arokia V.A. Mariadoss*, Ramachandran Vinyagam, Vinothkumar Rajamanickam, Vijayalakshmi Sankaran, Sathish Venkatesan and Ernest David*


DOI: 10.2174/1389557519666190311154425


Review Article

A review exploring therapeutic worth of 1,3,4-Oxadiazole tailored compounds

, 2019; 19(6): 477-509.

Garima Verma, Mohemmed F. Khan, Wasim Akhtar, Mohammad Mumtaz Alam, Mymoona Akhter and Mohammad Shaquiquzzaman*


DOI: 10.2174/1389557518666181015152433


Systemic Review Article

Clinical management of oral lichen planus: A systematic review

, 2019; 19(13): 1049-1059.

Luca Oberti, Lucchese Alberta, Petruzzi Massimo, Carinci Francesco and Lauritano Dorina*


DOI: 10.2174/1389557519666190301144157


Review Article

Protective role of natural products in cisplatin-induced nephrotoxicity

, 2019; 19(14): 1134-1143.

Nurul Raudzah Adib Ridzuan, Norhashima Abd Rashid, Faizah Othman, Siti Balkis Budin, Farida Hussan and Seong Lin Teoh*


DOI: 10.2174/1389557519666190320124438


Review Article

A review on anticancer potentials of benzothiazole derivatives

, 2020; 20(1): 12-23.

Nandini Pathak, Ekta Rathi, Nitesh Kumar*, Suvarna G. Kini and C. Mallikarjuna Rao


DOI: 10.2174/1389557519666190617153213


Review Article

Benzimidazole: A milestone in the field of medicinal chemistry

, 2020; 20(7): 532-565.

Mahesh S. Vasava, Manoj N. Bhoi, Sanjay K. Rathwa, Divya J. Jethava, Prachi T. Acharya, Dhaval B. Patel and Hitesh D. Patel*


DOI: 10.2174/1389557519666191122125453


Review Article

A review on quinoline derived scaffolds as anti-HIV agents

, 2019; 19(6): 510-526.

Nisha Chokkar, Sourav Kalra, Monika Chauhan and Raj Kumar*


DOI: 10.2174/1389557518666181018163448


Review Article

Parkinson’s disease: A review from pathophysiology to treatment

, 2020; 20(9): 754-767.

Bianca L.B. Marino, Lucilene R. de Souza, Kessia P.A. Sousa, Jaderson V. Ferreira, Elias C. Padilha, Carlos H.T.P. da Silva, Carlton A. Taft and Lorane I.S. Hage-Melim*


DOI: 10.2174/1389557519666191104110908



Review Article

Marine natural product bis-indole alkaloid caulerpin: Chemistry and biology

, 2019; 19(9): 751-761.

Jignesh Lunagariya, Poonam Bhadja, Shenghui Zhong, Rohit Vekariya and Shihai Xu*


DOI: 10.2174/1389557517666170927154231


General Review Article

Biological nanofactories: Using living forms for metal nanoparticle synthesis

, 2021; 21(2): 245-265.

Shilpi Srivastava, Zeba Usmani, Atanas G. Atanasov, Vinod Kumar Singh, Nagendra Pratap Singh, Ahmed M. Abdel-Azeem, Ram Prasad, Govind Gupta, Minaxi Sharma* and Atul Bhargava*


DOI: 10.2174/1389557520999201116163012


Review Article

Synthesis and biological activity of hydrazones and derivatives: A review

, 2020; 20(5): 342-368.

Juliana de Oliveira Carneiro Brum*, Tanos Celmar Costa França, Steven R. LaPlante and José Daniel Figueroa Villar


DOI: 10.2174/1389557519666191014142448



Most Accessed Articles

Biological Nanofactories: Using Living Forms for Metal Nanoparticle Synthesis

, 2021; 21(2): 245-265.

Srivastava, Shilpi; Usmani, Zeba; Atanasov, Atanas G.; Singh, Vinod Kumar; Singh, Nagendra Pratap; Abdel-Azeem, Ahmed M.; Prasad, Ram; Gupta, Govind; Sharma, Minaxi; Bhargava, Atul


DOI: 10.2174/1389557520999201116163012






Current and Advanced Nanomaterials in Dentistry as Regeneration Agents: An Update

, 2021; 21(7): 899-918.

Yazdanian, Mohsen; Rahmani, Aghil; Tahmasebi, Elahe; Tebyanian, Hamid; Yazdanian, Alireza; Mosaddad, Seyed Ali


DOI: 10.2174/1389557520666201124143449




Virtual Screening of Natural Products Database

, 2021; 21(18): 2655-2728.

de Sousa Luis, Jose Alixandre; Costa Barros, Renata Priscila; de Sousa, Natalia Ferreira; Muratov, Eugene; Scotti, Luciana; Scotti, Marcus Tullius


DOI: 10.2174/1389557520666200730161549





Current Insights into the Chemistry and Antitubercular Potential of Benzimidazole and Imidazole Derivatives

, 2021; 21(5): 633-647.

Parwani, Deepa; Bhattacharya, Sushanta; Rathore, Akash; Mallick, Chaitali; Asati, Vivek; Agarwal, Shivangi; Rajoriya, Vaibhav; Das, Ratnesh; Kashaw, Sushil Kumar


DOI: 10.2174/1389557520666201102094401



Effectiveness of Azithromycin as add-on Therapy in COVID-19 Management

, 2021; 21(19): 2860-2873.

Wahab, Shadma; Ahmad, Md Faruque; Hussain, Arshad; Usmani, Shazia; Shoaib, Ambreen; Ahmad, Wasim


DOI: 10.2174/1389557521666210401093948




Co-Editors

graphic
Muhammad Iqbal Choudhary
(27325 citations)
H.E.J. Research Institute of Chemistry
University of Karachi
Karachi
(Pakistan)
Biography
graphic
Alessandro Granito
University of Bologna
Diparitmento Di Scienze Mediche E Chirurgiche
Bologna
(Italy)
graphic
Davide Barreca
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences
University of Messina
Messina
(Italy)
Biography
View Full Editorial Board

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Journal History

Mini-Reviews in Medicinal Chemistry was launched in 2001. Dr. Atta-ur-Rahman, Dr. M. Iqbal Choudhary and Dr. Davide Barreca are the Co-Editors of the journal.

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